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Journal Abstract Search

164 related items for PubMed ID: 21346758

  • 1. Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil.
    Kharasch ED, Vangveravong S, Buck N, London A, Kim T, Blood J, Mach RH.
    Clin Pharmacol Ther; 2011 Apr; 89(4):562-70. PubMed ID: 21346758
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  • 3. Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimal and noninvasive probes for hepatic and first-pass CYP3A induction.
    Kharasch ED, Francis A, London A, Frey K, Kim T, Blood J.
    Clin Pharmacol Ther; 2011 Jul; 90(1):100-8. PubMed ID: 21562488
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  • 4. Single-point sampling for assessment of constitutive, induced, and inhibited cytochrome P450 3A activity with alfentanil or midazolam.
    Chaobal HN, Kharasch ED.
    Clin Pharmacol Ther; 2005 Nov; 78(5):529-39. PubMed ID: 16321619
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  • 5. Sensitivity of intravenous and oral alfentanil and pupillary miosis as minimally invasive and noninvasive probes for hepatic and first-pass CYP3A activity.
    Kharasch ED, Walker A, Hoffer C, Sheffels P.
    J Clin Pharmacol; 2005 Oct; 45(10):1187-97. PubMed ID: 16172184
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  • 8. Paradoxical role of cytochrome P450 3A in the bioactivation and clinical effects of levo-alpha-acetylmethadol: importance of clinical investigations to validate in vitro drug metabolism studies.
    Kharasch ED, Whittington D, Hoffer C, Krudys K, Craig K, Vicini P, Sheffels P, Lalovic B.
    Clin Pharmacokinet; 2005 Oct; 44(7):731-51. PubMed ID: 15966756
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  • 10. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone.
    Kharasch ED, Hoffer C, Whittington D, Sheffels P.
    Clin Pharmacol Ther; 2004 Sep; 76(3):250-69. PubMed ID: 15371986
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  • 11. Influence of CYP3A5 genotype on the pharmacokinetics and pharmacodynamics of the cytochrome P4503A probes alfentanil and midazolam.
    Kharasch ED, Walker A, Isoherranen N, Hoffer C, Sheffels P, Thummel K, Whittington D, Ensign D.
    Clin Pharmacol Ther; 2007 Oct; 82(4):410-26. PubMed ID: 17554244
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  • 12. Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A).
    Kharasch ED, Bedynek PS, Hoffer C, Walker A, Whittington D.
    Anesthesiology; 2012 Feb; 116(2):432-47. PubMed ID: 22273859
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  • 16. The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity.
    Gorski JC, Vannaprasaht S, Hamman MA, Ambrosius WT, Bruce MA, Haehner-Daniels B, Hall SD.
    Clin Pharmacol Ther; 2003 Sep; 74(3):275-87. PubMed ID: 12966371
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  • 19. Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir.
    Kharasch ED, Hoffer C, Whittington D, Walker A, Bedynek PS.
    Anesthesiology; 2009 Mar; 110(3):660-72. PubMed ID: 19225389
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  • 20. Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults.
    Yang J, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Stoch SA, Bertino JS, Nafziger AN, Ma JD.
    J Clin Pharmacol; 2019 Nov; 59(11):1495-1504. PubMed ID: 31051051
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