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205 related items for PubMed ID: 21349265

  • 1. Lafutidine, a unique histamine H2-receptor antagonist, inhibits distention-induced gastric acid secretion through an H2 receptor-independent mechanism.
    Nakano M, Kitano S, Nanri M, Kiniwa M.
    Eur J Pharmacol; 2011 May 11; 658(2-3):236-41. PubMed ID: 21349265
    [Abstract] [Full Text] [Related]

  • 2. Intestinal protection by lafutidine, a histamine H(2)-receptor antagonist, against indomethacin-induced damage in rats--role of endogenous nitric oxide.
    Tanaka A, Mizoguchi H, Hase S, Miyazawa T, Takeuchi K.
    Med Sci Monit; 2001 May 11; 7(5):869-77. PubMed ID: 11535926
    [Abstract] [Full Text] [Related]

  • 3. Protective effect of lafutidine, a histamine H2 receptor antagonist, against loxoprofen-induced small intestinal lesions in rats.
    Amagase K, Ochi A, Sugihara T, Kato S, Takeuchi K.
    J Gastroenterol Hepatol; 2010 May 11; 25 Suppl 1():S111-8. PubMed ID: 20586851
    [Abstract] [Full Text] [Related]

  • 4. Modulation by endogenous nitric oxide of acid secretion induced by gastric distention in rats: enhancement by nitric oxide synthase inhibitor.
    Kitamura M, Sugamoto S, Kawauchi S, Kato S, Takeuchi K.
    J Pharmacol Exp Ther; 1999 Oct 11; 291(1):181-7. PubMed ID: 10490902
    [Abstract] [Full Text] [Related]

  • 5. Afferent signalling from the acid-challenged rat stomach is inhibited and gastric acid elimination is enhanced by lafutidine.
    Edelsbrunner ME, Nakano M, Holzer P.
    BMC Gastroenterol; 2009 Jun 02; 9():40. PubMed ID: 19490646
    [Abstract] [Full Text] [Related]

  • 6. Lafutidine, a novel histamine H2-receptor antagonist, increases serum calcitonin gene-related peptide in rats after water immersion-restraint stress.
    Sato H, Kawashima K, Yuki M, Kazumori H, Rumi MA, Ortega-Cava CF, Ishihara S, Kinoshita Y.
    J Lab Clin Med; 2003 Feb 02; 141(2):102-5. PubMed ID: 12577045
    [Abstract] [Full Text] [Related]

  • 7. Possible involvement of host defense mechanism in the suppression of rat acute reflux esophagitis by the particular histamine H2 receptor antagonist lafutidine.
    Nakano M, Ajioka H, Abe M, Kiniwa M.
    Pharmacology; 2012 Feb 02; 90(3-4):205-11. PubMed ID: 23038658
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of neutrophil activation by lafutidine, an H2-receptor antagonist, through enhancement of sensory neuron activation contributes to the reduction of stress-induced gastric mucosal injury in rats.
    Harada N, Okajima K.
    Dig Dis Sci; 2007 Feb 02; 52(2):469-77. PubMed ID: 17211693
    [Abstract] [Full Text] [Related]

  • 9. Effect of Helicobacter pylori status on intragastric pH during administration of lafutidine or famotidine.
    Koike T, Ohara S, Sehine H, Kawamura M, Abe Y, Inomata Y, Iijima K, Imatani A, Shimosegawa T.
    Hepatogastroenterology; 2007 Jun 02; 54(76):1280-4. PubMed ID: 17629089
    [Abstract] [Full Text] [Related]

  • 10. Gastro-protective action of lafutidine mediated by capsaicin-sensitive afferent neurons without interaction with TRPV1 and involvement of endogenous prostaglandins.
    Fukushima K, Aoi Y, Kato S, Takeuchi K.
    World J Gastroenterol; 2006 May 21; 12(19):3031-7. PubMed ID: 16718783
    [Abstract] [Full Text] [Related]

  • 11. Lafutidine, a newly developed antiulcer drug, elevates postprandial intragastric pH and increases plasma calcitonin gene-related peptide and somatostatin concentrations in humans: comparisons with famotidine.
    Shimatani T, Inoue M, Kuroiwa T, Xu J, Nakamura M, Tazuma S, Ikawa K, Morikawa N.
    Dig Dis Sci; 2006 Jan 21; 51(1):114-20. PubMed ID: 16416222
    [Abstract] [Full Text] [Related]

  • 12. Prophylactic effect of lafutidine against the adverse reaction induced in rat stomach by repeated administration of 5-fluorouracil.
    Kotani T, Nakagiri A, Murashima Y, Takeuchi K.
    Inflammopharmacology; 2007 Oct 21; 15(5):203-8. PubMed ID: 17943252
    [Abstract] [Full Text] [Related]

  • 13. Effect of lafutidine, a novel histamine H2-receptor antagonist, on monochloramine-induced gastric lesions in rats: role of capsaicin-sensitive sensory neurons.
    Umeda M, Fujita A, Nishiwaki H, Takeuchi K.
    J Gastroenterol Hepatol; 1999 Sep 21; 14(9):859-65. PubMed ID: 10535466
    [Abstract] [Full Text] [Related]

  • 14. Effect of lafutidine, a histamine H2-receptor antagonist, on gastric mucosal blood flow and duodenal HCO3- secretion in rats: relation to capsaicin-sensitive afferent neurons.
    Mimaki H, Kagawa S, Aoi M, Kato S, Satoshi T, Kohama K, Takeuchi K.
    Dig Dis Sci; 2002 Dec 21; 47(12):2696-703. PubMed ID: 12498288
    [Abstract] [Full Text] [Related]

  • 15. Effects of the new H2-receptor antagonist 3-amino-4-[4- [4- (1-piperidinomethyl)-2-pyridyloxy]-cis-2-butenylamino]-3-cyclobutene-1, 2- dione hydrochloride on gastric acid secretion and ulceration.
    Muramatsu M, Isobe Y, Arai I, Hirose-Kijima H, Usuki-Ito C, Nagai H, Aihara H, Otomo S.
    Arzneimittelforschung; 1990 Jan 21; 40(1):49-54. PubMed ID: 1971169
    [Abstract] [Full Text] [Related]

  • 16. Antisecretory and antilesional effect of a new histamine H2-receptor antagonist, IT-066, in rats.
    Isobe Y, Nagai H, Muramatsu M, Aihara H, Otomo S.
    J Pharmacol Exp Ther; 1990 Dec 21; 255(3):1078-82. PubMed ID: 1979811
    [Abstract] [Full Text] [Related]

  • 17. Ghrelin stimulates gastric acid secretion and motility in rats.
    Masuda Y, Tanaka T, Inomata N, Ohnuma N, Tanaka S, Itoh Z, Hosoda H, Kojima M, Kangawa K.
    Biochem Biophys Res Commun; 2000 Oct 05; 276(3):905-8. PubMed ID: 11027567
    [Abstract] [Full Text] [Related]

  • 18. Sensitizing effects of lafutidine on CGRP-containing afferent nerves in the rat stomach.
    Nishihara K, Nozawa Y, Nakano M, Ajioka H, Matsuura N.
    Br J Pharmacol; 2002 Mar 05; 135(6):1487-94. PubMed ID: 11906962
    [Abstract] [Full Text] [Related]

  • 19. Role of nitric oxide in regulation of gastric acid secretion in rats: effects of NO donors and NO synthase inhibitor.
    Kato S, Kitamura M, Korolkiewicz RP, Takeuchi K.
    Br J Pharmacol; 1998 Mar 05; 123(5):839-46. PubMed ID: 9535011
    [Abstract] [Full Text] [Related]

  • 20. Potent and long-lasting action of lafutidine on the human histamine H(2) receptor.
    Fukushima Y, Otsuka H, Ishikawa M, Asano T, Anai M, Katsube T, Ogawa K, Kajiwara T, Ohkawa S, Ishikawa T, Omata M, Saitoh T.
    Digestion; 2001 Mar 05; 64(3):155-60. PubMed ID: 11786663
    [Abstract] [Full Text] [Related]

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