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102 related items for PubMed ID: 21362431

  • 1. Biological and chemical studies on aryl hydrocarbon receptor induction by the p53 inhibitor pifithrin-α and its condensation product pifithrin-β.
    Fernández-Cruz ML, Valdehita A, Alonso M, Mann E, Herradón B, Navas JM.
    Life Sci; 2011 Apr 25; 88(17-18):774-83. PubMed ID: 21362431
    [Abstract] [Full Text] [Related]

  • 2. The p53 inhibitor pifithrin-alpha is a potent agonist of the aryl hydrocarbon receptor.
    Hoagland MS, Hoagland EM, Swanson HI.
    J Pharmacol Exp Ther; 2005 Aug 25; 314(2):603-10. PubMed ID: 15843497
    [Abstract] [Full Text] [Related]

  • 3. Potent inhibition of carcinogen-bioactivating cytochrome P450 1B1 by the p53 inhibitor pifithrin alpha.
    Sparfel L, Van Grevenynghe J, Le Vee M, Aninat C, Fardel O.
    Carcinogenesis; 2006 Mar 25; 27(3):656-63. PubMed ID: 16258175
    [Abstract] [Full Text] [Related]

  • 4. Pifithrin-alpha promotes p53-mediated apoptosis in JB6 cells.
    Kaji A, Zhang Y, Nomura M, Bode AM, Ma WY, She QB, Dong Z.
    Mol Carcinog; 2003 Jul 25; 37(3):138-48. PubMed ID: 12884365
    [Abstract] [Full Text] [Related]

  • 5. Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation.
    Murphy PJ, Galigniana MD, Morishima Y, Harrell JM, Kwok RP, Ljungman M, Pratt WB.
    J Biol Chem; 2004 Jul 16; 279(29):30195-201. PubMed ID: 15145929
    [Abstract] [Full Text] [Related]

  • 6. Induction of cytochrome P4501A (CYP1A) by clotrimazole, a non-planar aromatic compound. Computational studies on structural features of clotrimazole and related imidazole derivatives.
    Navas JM, Chana A, Herradón B, Segner H.
    Life Sci; 2004 Dec 24; 76(6):699-714. PubMed ID: 15567194
    [Abstract] [Full Text] [Related]

  • 7. Pifithrin-α enhancing anticancer effect of topotecan on p53-expressing cancer cells.
    Guo J, Tang Q, Wang Q, Sun W, Pu Z, Wang J, Bao Y.
    Eur J Pharm Sci; 2019 Feb 01; 128():61-72. PubMed ID: 30472223
    [Abstract] [Full Text] [Related]

  • 8. p53 inhibitor pifithrin alpha can suppress heat shock and glucocorticoid signaling pathways.
    Komarova EA, Neznanov N, Komarov PG, Chernov MV, Wang K, Gudkov AV.
    J Biol Chem; 2003 May 02; 278(18):15465-8. PubMed ID: 12637507
    [Abstract] [Full Text] [Related]

  • 9. Modulation of Ah receptor and CYP1A1 expression by alpha-naphthoflavone in rainbow trout hepatocytes.
    Aluru N, Vuori K, Vijayan MM.
    Comp Biochem Physiol C Toxicol Pharmacol; 2005 May 02; 141(1):40-9. PubMed ID: 15949971
    [Abstract] [Full Text] [Related]

  • 10. Pifithrin-α alters p53 post-translational modifications pattern and differentially inhibits p53 target genes.
    Zhu J, Singh M, Selivanova G, Peuget S.
    Sci Rep; 2020 Jan 23; 10(1):1049. PubMed ID: 31974452
    [Abstract] [Full Text] [Related]

  • 11. Pifithrin-alpha enhances chemosensitivity by a p38 mitogen-activated protein kinase-dependent modulation of the eukaryotic initiation factor 4E in malignant cholangiocytes.
    Wehbe H, Henson R, Lang M, Meng F, Patel T.
    J Pharmacol Exp Ther; 2006 Dec 23; 319(3):1153-61. PubMed ID: 16982703
    [Abstract] [Full Text] [Related]

  • 12. One-way inhibiting cross-talk between arylhydrocarbon receptor (AhR) and estrogen receptor (ER) signaling in primary cultures of rainbow trout hepatocytes.
    Gräns J, Wassmur B, Celander MC.
    Aquat Toxicol; 2010 Nov 01; 100(3):263-70. PubMed ID: 20739074
    [Abstract] [Full Text] [Related]

  • 13. Decabromobiphenyl (PBB-209) activates the aryl hydrocarbon receptor while decachlorobiphenyl (PCB-209) is inactive: experimental evidence and computational rationalization of the different behavior of some halogenated biphenyls.
    Alonso M, Casado S, Miranda C, Tarazona JV, Navas JM, Herradón B.
    Chem Res Toxicol; 2008 Mar 01; 21(3):643-58. PubMed ID: 18311929
    [Abstract] [Full Text] [Related]

  • 14. An evaluation of the ability of pifithrin-alpha and -beta to inhibit p53 function in two wild-type p53 human tumor cell lines.
    Walton MI, Wilson SC, Hardcastle IR, Mirza AR, Workman P.
    Mol Cancer Ther; 2005 Sep 01; 4(9):1369-77. PubMed ID: 16170029
    [Abstract] [Full Text] [Related]

  • 15. The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro.
    Rocha S, Campbell KJ, Roche KC, Perkins ND.
    BMC Mol Biol; 2003 Sep 11; 4():9. PubMed ID: 12967348
    [Abstract] [Full Text] [Related]

  • 16. Suppression of high-fidelity double-strand break repair in mammalian chromosomes by pifithrin-alpha, a chemical inhibitor of p53.
    Lin Y, Waldman BC, Waldman AS.
    DNA Repair (Amst); 2003 Jan 02; 2(1):1-11. PubMed ID: 12509264
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of p73 function by Pifithrin-alpha as revealed by studies in zebrafish embryos.
    Davidson W, Ren Q, Kari G, Kashi O, Dicker AP, Rodeck U.
    Cell Cycle; 2008 May 01; 7(9):1224-30. PubMed ID: 18418056
    [Abstract] [Full Text] [Related]

  • 18. 2-(4-Amino-3-methylphenyl)-5-fluorobenzothiazole is a ligand and shows species-specific partial agonism of the aryl hydrocarbon receptor.
    Bazzi R, Bradshaw TD, Rowlands JC, Stevens MF, Bell DR.
    Toxicol Appl Pharmacol; 2009 May 15; 237(1):102-10. PubMed ID: 19265716
    [Abstract] [Full Text] [Related]

  • 19. Possible involvement of NO in the stimulating effect of pifithrins on survival of hemopoietic clonogenic cells.
    Proskuryakov SY, Konoplyannikov AG, Konoplyannikova OA, Shevchenko LI, Verkhovskii YG, Tsyb AF.
    Biochemistry (Mosc); 2009 Feb 15; 74(2):130-6. PubMed ID: 19267667
    [Abstract] [Full Text] [Related]

  • 20. Effects of p53 inhibitor on survival and death of cells subjected to oxidative stress.
    Strosznajder RP, Jesko H, Banasik M, Tanaka S.
    J Physiol Pharmacol; 2005 Sep 15; 56 Suppl 4():215-21. PubMed ID: 16204796
    [Abstract] [Full Text] [Related]

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