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203 related items for PubMed ID: 21364655

  • 1. XIAP impairs Smac release from the mitochondria during apoptosis.
    Flanagan L, Sebastià J, Tuffy LP, Spring A, Lichawska A, Devocelle M, Prehn JH, Rehm M.
    Cell Death Dis; 2010 Jun 03; 1(6):e49. PubMed ID: 21364655
    [Abstract] [Full Text] [Related]

  • 2. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 3. Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization.
    Flanagan L, Sebastia J, Delgado ME, Lennon JC, Rehm M.
    Biochim Biophys Acta; 2011 May 04; 1813(5):819-26. PubMed ID: 21354220
    [Abstract] [Full Text] [Related]

  • 4. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP, Bonavida B.
    Mol Cancer Ther; 2002 Oct 04; 1(12):1051-8. PubMed ID: 12481428
    [Abstract] [Full Text] [Related]

  • 5. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.
    MacFarlane M, Merrison W, Bratton SB, Cohen GM.
    J Biol Chem; 2002 Sep 27; 277(39):36611-6. PubMed ID: 12121969
    [Abstract] [Full Text] [Related]

  • 6. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P.
    Cancer Res; 2001 Oct 01; 61(19):7339-48. PubMed ID: 11585775
    [Abstract] [Full Text] [Related]

  • 7. Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.
    Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR.
    Cell Death Differ; 2014 Dec 01; 21(12):1862-76. PubMed ID: 25080938
    [Abstract] [Full Text] [Related]

  • 8. Fibroblast growth factor 2-mediated translational control of IAPs blocks mitochondrial release of Smac/DIABLO and apoptosis in small cell lung cancer cells.
    Pardo OE, Lesay A, Arcaro A, Lopes R, Ng BL, Warne PH, McNeish IA, Tetley TD, Lemoine NR, Mehmet H, Seckl MJ, Downward J.
    Mol Cell Biol; 2003 Nov 01; 23(21):7600-10. PubMed ID: 14560006
    [Abstract] [Full Text] [Related]

  • 9. BID-dependent release of mitochondrial SMAC dampens XIAP-mediated immunity against Shigella.
    Andree M, Seeger JM, Schüll S, Coutelle O, Wagner-Stippich D, Wiegmann K, Wunderlich CM, Brinkmann K, Broxtermann P, Witt A, Fritsch M, Martinelli P, Bielig H, Lamkemeyer T, Rugarli EI, Kaufmann T, Sterner-Kock A, Wunderlich FT, Villunger A, Martins LM, Krönke M, Kufer TA, Utermöhlen O, Kashkar H.
    EMBO J; 2014 Oct 01; 33(19):2171-87. PubMed ID: 25056906
    [Abstract] [Full Text] [Related]

  • 10. Interaction between XIAP and Smac/DIABLO in the mouse brain after transient focal cerebral ischemia.
    Saito A, Hayashi T, Okuno S, Ferrand-Drake M, Chan PH.
    J Cereb Blood Flow Metab; 2003 Sep 01; 23(9):1010-9. PubMed ID: 12973017
    [Abstract] [Full Text] [Related]

  • 11. Smac3, a novel Smac/DIABLO splicing variant, attenuates the stability and apoptosis-inhibiting activity of X-linked inhibitor of apoptosis protein.
    Fu J, Jin Y, Arend LJ.
    J Biol Chem; 2003 Dec 26; 278(52):52660-72. PubMed ID: 14523016
    [Abstract] [Full Text] [Related]

  • 12. The kinetics of translocation of Smac/DIABLO from the mitochondria to the cytosol in HeLa cells.
    Springs SL, Diavolitsis VM, Goodhouse J, McLendon GL.
    J Biol Chem; 2002 Nov 29; 277(48):45715-8. PubMed ID: 12364342
    [Abstract] [Full Text] [Related]

  • 13. X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
    Roa WH, Chen H, Fulton D, Gulavita S, Shaw A, Th'ng J, Farr-Jones M, Moore R, Petruk K.
    Clin Invest Med; 2003 Oct 29; 26(5):231-42. PubMed ID: 14596484
    [Abstract] [Full Text] [Related]

  • 14. Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.
    Owens TW, Foster FM, Valentijn A, Gilmore AP, Streuli CH.
    J Biol Chem; 2010 Jan 08; 285(2):1081-8. PubMed ID: 19875445
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  • 18. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.
    Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T.
    Nat Cell Biol; 2017 Apr 08; 19(4):318-328. PubMed ID: 28288130
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  • 20. A dimeric Smac/diablo peptide directly relieves caspase-3 inhibition by XIAP. Dynamic and cooperative regulation of XIAP by Smac/Diablo.
    Gao Z, Tian Y, Wang J, Yin Q, Wu H, Li YM, Jiang X.
    J Biol Chem; 2007 Oct 19; 282(42):30718-27. PubMed ID: 17724022
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