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Journal Abstract Search

244 related items for PubMed ID: 21367493

  • 21.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 22. Synthesis, biological evaluation of 9-N-substituted berberine derivatives as multi-functional agents of antioxidant, inhibitors of acetylcholinesterase, butyrylcholinesterase and amyloid-β aggregation.
    Shan WJ, Huang L, Zhou Q, Meng FC, Li XS.
    Eur J Med Chem; 2011 Dec; 46(12):5885-93. PubMed ID: 22019228
    [Abstract] [Full Text] [Related]

  • 23.
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  • 24. Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
    Li RS, Wang XB, Hu XJ, Kong LY.
    Bioorg Med Chem Lett; 2013 May 01; 23(9):2636-41. PubMed ID: 23511019
    [Abstract] [Full Text] [Related]

  • 25. Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer's disease.
    Li Y, Qiang X, Li Y, Yang X, Luo L, Xiao G, Cao Z, Tan Z, Deng Y.
    Bioorg Med Chem Lett; 2016 Apr 15; 26(8):2035-9. PubMed ID: 26947607
    [Abstract] [Full Text] [Related]

  • 26. Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties.
    Guzior N, Bajda M, Skrok M, Kurpiewska K, Lewiński K, Brus B, Pišlar A, Kos J, Gobec S, Malawska B.
    Eur J Med Chem; 2015 Mar 06; 92():738-49. PubMed ID: 25621991
    [Abstract] [Full Text] [Related]

  • 27. Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease.
    Sang Z, Qiang X, Li Y, Yuan W, Liu Q, Shi Y, Ang W, Luo Y, Tan Z, Deng Y.
    Eur J Med Chem; 2015 Apr 13; 94():348-66. PubMed ID: 25778991
    [Abstract] [Full Text] [Related]

  • 28. 3D-QSAR studies of azaoxoisoaporphine, oxoaporphine, and oxoisoaporphine derivatives as anti-AChE and anti-AD agents by the CoMFA method.
    Li YP, Weng X, Ning FX, Ou JB, Hou JQ, Luo HB, Li D, Huang ZS, Huang SL, Gu LQ.
    J Mol Graph Model; 2013 Apr 13; 41():61-7. PubMed ID: 23500628
    [Abstract] [Full Text] [Related]

  • 29. Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.
    Tasso B, Catto M, Nicolotti O, Novelli F, Tonelli M, Giangreco I, Pisani L, Sparatore A, Boido V, Carotti A, Sparatore F.
    Eur J Med Chem; 2011 Jun 13; 46(6):2170-84. PubMed ID: 21459491
    [Abstract] [Full Text] [Related]

  • 30. Syntheses of coumarin-tacrine hybrids as dual-site acetylcholinesterase inhibitors and their activity against butylcholinesterase, Aβ aggregation, and β-secretase.
    Sun Q, Peng DY, Yang SG, Zhu XL, Yang WC, Yang GF.
    Bioorg Med Chem; 2014 Sep 01; 22(17):4784-91. PubMed ID: 25088549
    [Abstract] [Full Text] [Related]

  • 31. Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.
    Rosini M, Simoni E, Bartolini M, Cavalli A, Ceccarini L, Pascu N, McClymont DW, Tarozzi A, Bolognesi ML, Minarini A, Tumiatti V, Andrisano V, Mellor IR, Melchiorre C.
    J Med Chem; 2008 Aug 14; 51(15):4381-4. PubMed ID: 18605718
    [Abstract] [Full Text] [Related]

  • 32. Synthesis, biological evaluation and molecular modeling of oxoisoaporphine and oxoaporphine derivatives as new dual inhibitors of acetylcholinesterase/butyrylcholinesterase.
    Tang H, Wei YB, Zhang C, Ning FX, Qiao W, Huang SL, Ma L, Huang ZS, Gu LQ.
    Eur J Med Chem; 2009 Jun 14; 44(6):2523-32. PubMed ID: 19243862
    [Abstract] [Full Text] [Related]

  • 33. Clicked tacrine conjugates as acetylcholinesterase and β-amyloid directed compounds.
    Ouberai M, Brannstrom K, Vestling M, Olofsson A, Dumy P, Chierici S, Garcia J.
    Org Biomol Chem; 2011 Feb 21; 9(4):1140-7. PubMed ID: 21152577
    [Abstract] [Full Text] [Related]

  • 34. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
    [Abstract] [Full Text] [Related]

  • 35. Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer.
    Tumiatti V, Milelli A, Minarini A, Rosini M, Bolognesi ML, Micco M, Andrisano V, Bartolini M, Mancini F, Recanatini M, Cavalli A, Melchiorre C.
    J Med Chem; 2008 Nov 27; 51(22):7308-12. PubMed ID: 18954037
    [Abstract] [Full Text] [Related]

  • 36. Derivatives of oxoisoaporphine alkaloids: a novel class of selective acetylcholinesterase inhibitors.
    Tang H, Ning FX, Wei YB, Huang SL, Huang ZS, Chan AS, Gu LQ.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3765-8. PubMed ID: 17451950
    [Abstract] [Full Text] [Related]

  • 37. Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
    Brunhofer G, Fallarero A, Karlsson D, Batista-Gonzalez A, Shinde P, Gopi Mohan C, Vuorela P.
    Bioorg Med Chem; 2012 Nov 15; 20(22):6669-79. PubMed ID: 23062825
    [Abstract] [Full Text] [Related]

  • 38. [Design, synthesis and evaluation of bis-nicotine derivatives as inhibitors of cholinesterases and beta-amyloid aggregation].
    Luo W, Zhao YM, Tian RG, Su YB, Hong C.
    Yao Xue Xue Bao; 2013 Nov 15; 48(11):1671-6. PubMed ID: 24475704
    [Abstract] [Full Text] [Related]

  • 39. Rational modification of donepezil as multifunctional acetylcholinesterase inhibitors for the treatment of Alzheimer's disease.
    Wang ZM, Cai P, Liu QH, Xu DQ, Yang XL, Wu JJ, Kong LY, Wang XB.
    Eur J Med Chem; 2016 Nov 10; 123():282-297. PubMed ID: 27484514
    [Abstract] [Full Text] [Related]

  • 40. New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer's disease.
    Czarnecka K, Girek M, Maciejewska K, Skibiński R, Jończyk J, Bajda M, Kabziński J, Sołowiej P, Majsterek I, Szymański P.
    J Enzyme Inhib Med Chem; 2017 Dec 10; 33(1):158-170. PubMed ID: 29210299
    [Abstract] [Full Text] [Related]

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