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Journal Abstract Search

186 related items for PubMed ID: 2136817

  • 1. Pathophysiological actions of thromboxane A2 and their pharmacological antagonism by thromboxane receptor blockade with GR32191.
    Humphrey PP, Hallet P, Hornby EJ, Wallis CJ, Collington EW, Lumley P.
    Circulation; 1990 Jan; 81(1 Suppl):I42-52; discussion I59-60. PubMed ID: 2136817
    [Abstract] [Full Text] [Related]

  • 2. GR32191, a highly potent and specific thromboxane A2 receptor blocking drug on platelets and vascular and airways smooth muscle in vitro.
    Lumley P, White BP, Humphrey PP.
    Br J Pharmacol; 1989 Jul; 97(3):783-94. PubMed ID: 2527074
    [Abstract] [Full Text] [Related]

  • 3. Preliminary assessment of a novel thromboxane A2 receptor-blocking drug, GR32191, in healthy subjects.
    Thomas M, Lumley P.
    Circulation; 1990 Jan; 81(1 Suppl):I53-8; discussion I59-60. PubMed ID: 2136818
    [Abstract] [Full Text] [Related]

  • 4. Preliminary clinical studies with thromboxane synthase inhibitors and thromboxane receptor blockers. A review.
    Fiddler GI, Lumley P.
    Circulation; 1990 Jan; 81(1 Suppl):I69-78; discussion I79-80. PubMed ID: 2136820
    [Abstract] [Full Text] [Related]

  • 5. Thromboxane (Tx) A2 receptor blockade and TxA2 synthase inhibition alone and in combination: comparison of anti-aggregatory efficacy in human platelets.
    Watts IS, Wharton KA, White BP, Lumley P.
    Br J Pharmacol; 1991 Feb; 102(2):497-505. PubMed ID: 1826620
    [Abstract] [Full Text] [Related]

  • 6. On the mechanism of the prolonged action in man of GR32191, a thromboxane receptor antagonist.
    Ritter JM, Doktor HS, Benjamin N, Barrow SE, Stewart-Long P.
    Adv Prostaglandin Thromboxane Leukot Res; 1991 Feb; 21A():351-4. PubMed ID: 1825568
    [Abstract] [Full Text] [Related]

  • 7. The inhibitory effect of GR32191, a thromboxane receptor blocking drug, on human platelet aggregation, adhesion and secretion.
    Hornby EJ, Foster MR, McCabe PJ, Stratton LE.
    Thromb Haemost; 1989 Jun 30; 61(3):429-36. PubMed ID: 2529661
    [Abstract] [Full Text] [Related]

  • 8. Maximal blockade of TxA2 without compromised PGI2 formation; a superior profile of the TxA2 receptor blocking drug GR32191 over aspirin.
    Lumley P, Keery RJ, Wharton KA, White BP, Watts IS.
    Adv Prostaglandin Thromboxane Leukot Res; 1991 Jun 30; 21B():603-6. PubMed ID: 1825385
    [No Abstract] [Full Text] [Related]

  • 9. AH23848: a thromboxane receptor-blocking drug that can clarify the pathophysiologic role of thromboxane A2.
    Brittain RT, Boutal L, Carter MC, Coleman RA, Collington EW, Geisow HP, Hallett P, Hornby EJ, Humphrey PP, Jack D.
    Circulation; 1985 Dec 30; 72(6):1208-18. PubMed ID: 2998642
    [Abstract] [Full Text] [Related]

  • 10. Thromboxane A2 in cardiovascular and renal disorders: is there a defined role for thromboxane receptor antagonists or thromboxane synthase inhibitors?
    Smith EF.
    Eicosanoids; 1989 Dec 30; 2(4):199-212. PubMed ID: 2534279
    [Abstract] [Full Text] [Related]

  • 11. Pharmacology of thromboxane A2 receptor antagonists.
    Halushka PV.
    Z Kardiol; 1989 Dec 30; 78 Suppl 3():42-7. PubMed ID: 2530712
    [Abstract] [Full Text] [Related]

  • 12. Effect of a thromboxane receptor antagonist on PGD2- and allergen-induced bronchoconstriction.
    Beasley RC, Featherstone RL, Church MK, Rafferty P, Varley JG, Harris A, Robinson C, Holgate ST.
    J Appl Physiol (1985); 1989 Apr 30; 66(4):1685-93. PubMed ID: 2525122
    [Abstract] [Full Text] [Related]

  • 13. 7-Oxabicyclo[2.2.1]heptane analogs as modulators of the thromboxane A2 and prostacyclin receptors.
    Sprague PW, Heikes JE, Harris DN, Greenberg R.
    Adv Prostaglandin Thromboxane Leukot Res; 1983 Apr 30; 11():337-43. PubMed ID: 6303073
    [No Abstract] [Full Text] [Related]

  • 14. [Thromboxane antagonism in thrombocytes--pathophysiology, pharmacology and possible clinical significance].
    Schrör K.
    Wien Klin Wochenschr; 1991 Apr 30; 103(18):543-53. PubMed ID: 1836294
    [Abstract] [Full Text] [Related]

  • 15. Thromboxane receptor blockade attenuates the toxic effect of cyclosporine in experimental renal transplantation.
    Rossini M, Belloni A, Remuzzi G, Perico N.
    Circulation; 1990 Jan 30; 81(1 Suppl):I61-7; discussion I68. PubMed ID: 2136819
    [Abstract] [Full Text] [Related]

  • 16. R 68 070: thromboxane A2 synthetase inhibition and thromboxane A2/prostaglandin endoperoxide receptor blockade combined in one molecule--II. Pharmacological effects in vivo and ex vivo.
    De Clerck F, Beetens J, Van de Water A, Vercammen E, Janssen PA.
    Thromb Haemost; 1989 Feb 28; 61(1):43-9. PubMed ID: 2526385
    [Abstract] [Full Text] [Related]

  • 17. Platelet and vascular smooth muscle thromboxane A2/prostaglandin H2 receptors.
    Halushka PV, Mais DE, Saussy DL.
    Fed Proc; 1987 Jan 28; 46(1):149-53. PubMed ID: 2948839
    [Abstract] [Full Text] [Related]

  • 18. Role of proaggregatory and antiaggregatory prostaglandins in hemostasis. Studies with combined thromboxane synthase inhibition and thromboxane receptor antagonism.
    Gresele P, Arnout J, Deckmyn H, Huybrechts E, Pieters G, Vermylen J.
    J Clin Invest; 1987 Nov 28; 80(5):1435-45. PubMed ID: 2960694
    [Abstract] [Full Text] [Related]

  • 19. GR32191 and the role of thromboxane A2 in asthma--preclinical and clinical findings.
    Coleman RA.
    Agents Actions Suppl; 1991 Nov 28; 34():211-20. PubMed ID: 1793065
    [Abstract] [Full Text] [Related]

  • 20. Modulation by adenosine of thromboxane A2 receptor-mediated constriction in the human umbilical artery.
    Di Grande A, Malatino LS, Boura AL, Read MA, Walters WA.
    Int J Clin Pharmacol Ther; 1994 Jul 28; 32(7):344-6. PubMed ID: 7952795
    [Abstract] [Full Text] [Related]

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