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Journal Abstract Search

873 related items for PubMed ID: 21368833

  • 1. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
    Nature; 2011 Mar 03; 471(7336):104-9. PubMed ID: 21368833
    [Abstract] [Full Text] [Related]

  • 2. Mcl-1 ubiquitination and destruction.
    Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W.
    Oncotarget; 2011 Mar 03; 2(3):239-44. PubMed ID: 21608150
    [Abstract] [Full Text] [Related]

  • 3. The two faces of FBW7 in cancer drug resistance.
    Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W.
    Bioessays; 2011 Nov 03; 33(11):851-9. PubMed ID: 22006825
    [Abstract] [Full Text] [Related]

  • 4. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
    Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, Belmont LD, Kaminker JS, O'Rourke KM, Pujara K, Kohli PB, Johnson AR, Chiu ML, Lill JR, Jackson PK, Fairbrother WJ, Seshagiri S, Ludlam MJ, Leong KG, Dueber EC, Maecker H, Huang DC, Dixit VM.
    Nature; 2011 Mar 03; 471(7336):110-4. PubMed ID: 21368834
    [Abstract] [Full Text] [Related]

  • 5. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE.
    Proc Natl Acad Sci U S A; 2004 Jun 15; 101(24):9085-90. PubMed ID: 15150404
    [Abstract] [Full Text] [Related]

  • 6. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.
    J Biol Chem; 2015 Apr 17; 290(16):10368-81. PubMed ID: 25670854
    [Abstract] [Full Text] [Related]

  • 7. FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
    Tong J, Tan S, Zou F, Yu J, Zhang L.
    Oncogene; 2017 Feb 09; 36(6):787-796. PubMed ID: 27399335
    [Abstract] [Full Text] [Related]

  • 8. FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.
    Wang R, Wang Y, Liu N, Ren C, Jiang C, Zhang K, Yu S, Chen Y, Tang H, Deng Q, Fu C, Wang Y, Li R, Liu M, Pan W, Wang P.
    Cell Res; 2013 Jun 09; 23(6):803-19. PubMed ID: 23507969
    [Abstract] [Full Text] [Related]

  • 9. Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma.
    He L, Torres-Lockhart K, Forster N, Ramakrishnan S, Greninger P, Garnett MJ, McDermott U, Rothenberg SM, Benes CH, Ellisen LW.
    Cancer Discov; 2013 Mar 09; 3(3):324-37. PubMed ID: 23274910
    [Abstract] [Full Text] [Related]

  • 10. MicroRNA-223 regulates cyclin E activity by modulating expression of F-box and WD-40 domain protein 7.
    Xu Y, Sengupta T, Kukreja L, Minella AC.
    J Biol Chem; 2010 Nov 05; 285(45):34439-46. PubMed ID: 20826802
    [Abstract] [Full Text] [Related]

  • 11. Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
    Xiao D, Yue M, Su H, Ren P, Jiang J, Li F, Hu Y, Du H, Liu H, Qing G.
    Mol Cell; 2016 Nov 03; 64(3):493-506. PubMed ID: 27773673
    [Abstract] [Full Text] [Related]

  • 12. SCF(Fbw7) modulates the NFkB signaling pathway by targeting NFkB2 for ubiquitination and destruction.
    Fukushima H, Matsumoto A, Inuzuka H, Zhai B, Lau AW, Wan L, Gao D, Shaik S, Yuan M, Gygi SP, Jimi E, Asara JM, Nakayama K, Nakayama KI, Wei W.
    Cell Rep; 2012 May 31; 1(5):434-43. PubMed ID: 22708077
    [Abstract] [Full Text] [Related]

  • 13. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB, Dodard-Friedman I, Blank V.
    J Biol Chem; 2015 Oct 23; 290(43):26292-302. PubMed ID: 26306035
    [Abstract] [Full Text] [Related]

  • 14. F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.
    Sancho R, Jandke A, Davis H, Diefenbacher ME, Tomlinson I, Behrens A.
    Gastroenterology; 2010 Sep 23; 139(3):929-41. PubMed ID: 20638938
    [Abstract] [Full Text] [Related]

  • 15. Ehrlichia chaffeensis TRP120-mediated ubiquitination and proteasomal degradation of tumor suppressor FBW7 increases oncoprotein stability and promotes infection.
    Wang JY, Zhu B, Patterson LL, Rogan MR, Kibler CE, McBride JW.
    PLoS Pathog; 2020 Apr 23; 16(4):e1008541. PubMed ID: 32353058
    [Abstract] [Full Text] [Related]

  • 16. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K, Hiramatsu Y, Uchida C, Isobe T, Hattori T, Oda T, Shibata K, Nakamura S, Kikuchi A, Kitagawa M.
    Oncogene; 2009 Jun 25; 28(25):2393-405. PubMed ID: 19421138
    [Abstract] [Full Text] [Related]

  • 17. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T, Hattori T, Kitagawa K, Uchida C, Kotake Y, Kosugi I, Oda T, Kitagawa M.
    J Biol Chem; 2009 Oct 09; 284(41):27766-27779. PubMed ID: 19679664
    [Abstract] [Full Text] [Related]

  • 18. Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner.
    Kiprianova I, Remy J, Milosch N, Mohrenz IV, Seifert V, Aigner A, Kögel D.
    Neoplasia; 2015 Jul 09; 17(7):564-73. PubMed ID: 26297434
    [Abstract] [Full Text] [Related]

  • 19. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
    Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X.
    Cell Res; 2015 May 09; 25(5):561-73. PubMed ID: 25753158
    [Abstract] [Full Text] [Related]

  • 20. Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.
    Min SH, Lau AW, Lee TH, Inuzuka H, Wei S, Huang P, Shaik S, Lee DY, Finn G, Balastik M, Chen CH, Luo M, Tron AE, Decaprio JA, Zhou XZ, Wei W, Lu KP.
    Mol Cell; 2012 Jun 29; 46(6):771-83. PubMed ID: 22608923
    [Abstract] [Full Text] [Related]

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