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798 related items for PubMed ID: 21368834

  • 1. Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
    Wertz IE, Kusam S, Lam C, Okamoto T, Sandoval W, Anderson DJ, Helgason E, Ernst JA, Eby M, Liu J, Belmont LD, Kaminker JS, O'Rourke KM, Pujara K, Kohli PB, Johnson AR, Chiu ML, Lill JR, Jackson PK, Fairbrother WJ, Seshagiri S, Ludlam MJ, Leong KG, Dueber EC, Maecker H, Huang DC, Dixit VM.
    Nature; 2011 Mar 03; 471(7336):110-4. PubMed ID: 21368834
    [Abstract] [Full Text] [Related]

  • 2. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
    Nature; 2011 Mar 03; 471(7336):104-9. PubMed ID: 21368833
    [Abstract] [Full Text] [Related]

  • 3. The two faces of FBW7 in cancer drug resistance.
    Wang Z, Fukushima H, Gao D, Inuzuka H, Wan L, Lau AW, Liu P, Wei W.
    Bioessays; 2011 Nov 03; 33(11):851-9. PubMed ID: 22006825
    [Abstract] [Full Text] [Related]

  • 4. Mcl-1 ubiquitination and destruction.
    Inuzuka H, Fukushima H, Shaik S, Liu P, Lau AW, Wei W.
    Oncotarget; 2011 Mar 03; 2(3):239-44. PubMed ID: 21608150
    [Abstract] [Full Text] [Related]

  • 5. ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.
    Ji S, Qin Y, Shi S, Liu X, Hu H, Zhou H, Gao J, Zhang B, Xu W, Liu J, Liang D, Liu L, Liu C, Long J, Zhou H, Chiao PJ, Xu J, Ni Q, Gao D, Yu X.
    Cell Res; 2015 May 03; 25(5):561-73. PubMed ID: 25753158
    [Abstract] [Full Text] [Related]

  • 6. Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.
    Khan OM, Almagro J, Nelson JK, Horswell S, Encheva V, Keyan KS, Clurman BE, Snijders AP, Behrens A.
    Nat Commun; 2021 Apr 06; 12(1):2043. PubMed ID: 33824312
    [Abstract] [Full Text] [Related]

  • 7. FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.
    Tong J, Tan S, Zou F, Yu J, Zhang L.
    Oncogene; 2017 Feb 09; 36(6):787-796. PubMed ID: 27399335
    [Abstract] [Full Text] [Related]

  • 8. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.
    J Biol Chem; 2015 Apr 17; 290(16):10368-81. PubMed ID: 25670854
    [Abstract] [Full Text] [Related]

  • 9. Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
    Xiao D, Yue M, Su H, Ren P, Jiang J, Li F, Hu Y, Du H, Liu H, Qing G.
    Mol Cell; 2016 Nov 03; 64(3):493-506. PubMed ID: 27773673
    [Abstract] [Full Text] [Related]

  • 10. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase.
    Isobe T, Hattori T, Kitagawa K, Uchida C, Kotake Y, Kosugi I, Oda T, Kitagawa M.
    J Biol Chem; 2009 Oct 09; 284(41):27766-27779. PubMed ID: 19679664
    [Abstract] [Full Text] [Related]

  • 11. Cyclin-dependent kinase 1-mediated phosphorylation of YES links mitotic arrest and apoptosis during antitubulin chemotherapy.
    Wang Z, Chen X, Zhong MZ, Yang S, Zhou J, Klinkebiel DL, Karpf AR, Chen Y, Dong J.
    Cell Signal; 2018 Dec 09; 52():137-146. PubMed ID: 30223016
    [Abstract] [Full Text] [Related]

  • 12. Triggering Fbw7-mediated proteasomal degradation of c-Myc by oridonin induces cell growth inhibition and apoptosis.
    Huang HL, Weng HY, Wang LQ, Yu CH, Huang QJ, Zhao PP, Wen JZ, Zhou H, Qu LH.
    Mol Cancer Ther; 2012 May 09; 11(5):1155-65. PubMed ID: 22389469
    [Abstract] [Full Text] [Related]

  • 13. PTBP1 modulation of MCL1 expression regulates cellular apoptosis induced by antitubulin chemotherapeutics.
    Cui J, Placzek WJ.
    Cell Death Differ; 2016 Oct 09; 23(10):1681-90. PubMed ID: 27367564
    [Abstract] [Full Text] [Related]

  • 14. Targeting FBW7 as a Strategy to Overcome Resistance to Targeted Therapy in Non-Small Cell Lung Cancer.
    Ye M, Zhang Y, Zhang X, Zhang J, Jing P, Cao L, Li N, Li X, Yao L, Zhang J, Zhang J.
    Cancer Res; 2017 Jul 01; 77(13):3527-3539. PubMed ID: 28522751
    [Abstract] [Full Text] [Related]

  • 15. MCL1 meets its end during mitotic arrest.
    Millman SE, Pagano M.
    EMBO Rep; 2011 May 01; 12(5):384-5. PubMed ID: 21475247
    [No Abstract] [Full Text] [Related]

  • 16. Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).
    Kannan MB, Dodard-Friedman I, Blank V.
    J Biol Chem; 2015 Oct 23; 290(43):26292-302. PubMed ID: 26306035
    [Abstract] [Full Text] [Related]

  • 17. The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation.
    Welcker M, Orian A, Jin J, Grim JE, Harper JW, Eisenman RN, Clurman BE.
    Proc Natl Acad Sci U S A; 2004 Jun 15; 101(24):9085-90. PubMed ID: 15150404
    [Abstract] [Full Text] [Related]

  • 18. The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.
    Biswas M, Phan D, Watanabe M, Chan JY.
    J Biol Chem; 2011 Nov 11; 286(45):39282-9. PubMed ID: 21953459
    [Abstract] [Full Text] [Related]

  • 19. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K, Hiramatsu Y, Uchida C, Isobe T, Hattori T, Oda T, Shibata K, Nakamura S, Kikuchi A, Kitagawa M.
    Oncogene; 2009 Jun 25; 28(25):2393-405. PubMed ID: 19421138
    [Abstract] [Full Text] [Related]

  • 20. The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.
    Zhao D, Zheng HQ, Zhou Z, Chen C.
    Cancer Res; 2010 Jun 01; 70(11):4728-38. PubMed ID: 20484041
    [Abstract] [Full Text] [Related]

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