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927 related items for PubMed ID: 21371602
1. Advancing fragment binders to lead-like compounds using ligand and protein-based NMR spectroscopy. Maurer T. Methods Enzymol; 2011; 493():469-85. PubMed ID: 21371602 [Abstract] [Full Text] [Related]
6. Design and NMR-based screening of LEF, a library of chemical fragments with different local environment of fluorine. Vulpetti A, Hommel U, Landrum G, Lewis R, Dalvit C. J Am Chem Soc; 2009 Sep 16; 131(36):12949-59. PubMed ID: 19702332 [Abstract] [Full Text] [Related]
7. Recent progress in fragment-based lead discovery. Schulz MN, Hubbard RE. Curr Opin Pharmacol; 2009 Oct 16; 9(5):615-21. PubMed ID: 19477685 [Abstract] [Full Text] [Related]
10. Two 'Golden Ratio' indices in fragment-based drug discovery. Orita M, Ohno K, Niimi T. Drug Discov Today; 2009 Mar 16; 14(5-6):321-8. PubMed ID: 19028598 [Abstract] [Full Text] [Related]
12. From experimental design to validated hits a comprehensive walk-through of fragment lead identification using surface plasmon resonance. Giannetti AM. Methods Enzymol; 2011 Mar 16; 493():169-218. PubMed ID: 21371592 [Abstract] [Full Text] [Related]
13. Novel prostaglandin D synthase inhibitors generated by fragment-based drug design. Hohwy M, Spadola L, Lundquist B, Hawtin P, Dahmén J, Groth-Clausen I, Nilsson E, Persdotter S, von Wachenfeldt K, Folmer RH, Edman K. J Med Chem; 2008 Apr 10; 51(7):2178-86. PubMed ID: 18341273 [Abstract] [Full Text] [Related]
18. Process of Fragment-Based Lead Discovery-A Perspective from NMR. Ma R, Wang P, Wu J, Ruan K. Molecules; 2016 Jul 16; 21(7):. PubMed ID: 27438813 [Abstract] [Full Text] [Related]
19. Establish an automated flow injection ESI-MS method for the screening of fragment based libraries: Application to Hsp90. Riccardi Sirtori F, Caronni D, Colombo M, Dalvit C, Paolucci M, Regazzoni L, Visco C, Fogliatto G. Eur J Pharm Sci; 2015 Aug 30; 76():83-94. PubMed ID: 25952103 [Abstract] [Full Text] [Related]
20. NMR fragment screening: Advantages and applications. Schade M. IDrugs; 2006 Feb 30; 9(2):110-3. PubMed ID: 16523400 [Abstract] [Full Text] [Related] Page: [Next] [New Search]