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779 related items for PubMed ID: 21374707

  • 1. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.
    J Orthop Res; 2011 Aug; 29(8):1199-209. PubMed ID: 21374707
    [Abstract] [Full Text] [Related]

  • 2. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.
    J Agric Food Chem; 2012 Jan 18; 60(2):665-75. PubMed ID: 22148415
    [Abstract] [Full Text] [Related]

  • 3. Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.
    Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.
    Anticancer Res; 2011 May 18; 31(5):1691-702. PubMed ID: 21617228
    [Abstract] [Full Text] [Related]

  • 4. Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.
    Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.
    Hum Exp Toxicol; 2014 Mar 18; 33(3):270-83. PubMed ID: 23760257
    [Abstract] [Full Text] [Related]

  • 5. The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
    Liu KC, Huang YT, Wu PP, Ji BC, Yang JS, Yang JL, Chiu TH, Chueh FS, Chung JG.
    Int J Oncol; 2011 Mar 18; 38(3):787-96. PubMed ID: 21206973
    [Abstract] [Full Text] [Related]

  • 6. Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.
    Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.
    Free Radic Biol Med; 2014 Sep 18; 74():1-13. PubMed ID: 24952138
    [Abstract] [Full Text] [Related]

  • 7. Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells.
    Lee JW, Cho MK.
    Arch Pharm Res; 2008 Dec 18; 31(12):1604-12. PubMed ID: 19099231
    [Abstract] [Full Text] [Related]

  • 8. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 9. Benzyl isothiocyanate (BITC) induces apoptosis of GBM 8401 human brain glioblastoma multiforms cells via activation of caspase-8/Bid and the reactive oxygen species-dependent mitochondrial pathway.
    Shang HS, Shih YL, Lu TJ, Lee CH, Hsueh SC, Chou YC, Lu HF, Liao NC, Chung JG.
    Environ Toxicol; 2016 Dec 22; 31(12):1751-1760. PubMed ID: 28675694
    [Abstract] [Full Text] [Related]

  • 10. Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway.
    Chiu YJ, Hour MJ, Lu CC, Chung JG, Kuo SC, Huang WW, Chen HJ, Jin YA, Yang JS.
    J Orthop Res; 2011 Sep 22; 29(9):1448-56. PubMed ID: 21425328
    [Abstract] [Full Text] [Related]

  • 11. Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways.
    Huang WW, Ko SW, Tsai HY, Chung JG, Chiang JH, Chen KT, Chen YC, Chen HY, Chen YF, Yang JS.
    Int J Oncol; 2011 Apr 22; 38(4):1067-73. PubMed ID: 21271215
    [Abstract] [Full Text] [Related]

  • 12. Induction of mitotic arrest and apoptosis by a novel synthetic quinolone analogue, CWC-8, via intrinsic and extrinsic apoptotic pathways in human osteogenic sarcoma U-2 OS cells.
    Chang YH, Yang JS, Kuo SC, Chung JG.
    Anticancer Res; 2009 Aug 22; 29(8):3139-48. PubMed ID: 19661327
    [Abstract] [Full Text] [Related]

  • 13. Paclitaxel induces apoptosis via caspase-3 activation in human osteogenic sarcoma cells (U-2 OS).
    Lu KH, Lue KH, Chou MC, Chung JG.
    J Orthop Res; 2005 Sep 22; 23(5):988-94. PubMed ID: 16140185
    [Abstract] [Full Text] [Related]

  • 14. ERK-modulated intrinsic signaling and G(2)/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells.
    Tsai SC, Huang WW, Huang WC, Lu CC, Chiang JH, Peng SF, Chung JG, Lin YH, Hsu YM, Amagaya S, Yang JS.
    Int J Oncol; 2012 Dec 22; 41(6):2065-72. PubMed ID: 23008020
    [Abstract] [Full Text] [Related]

  • 15. Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
    Yan H, Zhu Y, Liu B, Wu H, Li Y, Wu X, Zhou Q, Xu K.
    Br J Nutr; 2011 Dec 22; 106(12):1779-91. PubMed ID: 21733335
    [Abstract] [Full Text] [Related]

  • 16. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
    Chiao JW, Wu H, Ramaswamy G, Conaway CC, Chung FL, Wang L, Liu D.
    Carcinogenesis; 2004 Aug 22; 25(8):1403-8. PubMed ID: 15016658
    [Abstract] [Full Text] [Related]

  • 17. Effects of phenylethyl isothiocyanate and its metabolite on cell-cycle arrest and apoptosis in LNCaP human prostate cancer cells.
    Hwang ES, Lee HJ.
    Int J Food Sci Nutr; 2010 May 22; 61(3):324-36. PubMed ID: 20402549
    [Abstract] [Full Text] [Related]

  • 18. Quercetin-induced apoptosis acts through mitochondrial- and caspase-3-dependent pathways in human breast cancer MDA-MB-231 cells.
    Chien SY, Wu YC, Chung JG, Yang JS, Lu HF, Tsou MF, Wood WG, Kuo SJ, Chen DR.
    Hum Exp Toxicol; 2009 Aug 22; 28(8):493-503. PubMed ID: 19755441
    [Abstract] [Full Text] [Related]

  • 19. Beta-phenylethyl isothiocyanate mediated apoptosis; contribution of Bax and the mitochondrial death pathway.
    Rose P, Armstrong JS, Chua YL, Ong CN, Whiteman M.
    Int J Biochem Cell Biol; 2005 Jan 22; 37(1):100-19. PubMed ID: 15381154
    [Abstract] [Full Text] [Related]

  • 20. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells.
    Kim BM, Choi YJ, Han Y, Yun YS, Hong SH.
    Toxicol Appl Pharmacol; 2009 Aug 15; 239(1):87-97. PubMed ID: 19481559
    [Abstract] [Full Text] [Related]

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