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Journal Abstract Search

149 related items for PubMed ID: 21374821

  • 1. Discovery and biological activity of 6BrCaQ as an inhibitor of the Hsp90 protein folding machinery.
    Audisio D, Messaoudi S, Cegielkowski L, Peyrat JF, Brion JD, Methy-Gonnot D, Radanyi C, Renoir JM, Alami M.
    ChemMedChem; 2011 May 02; 6(5):804-15. PubMed ID: 21374821
    [Abstract] [Full Text] [Related]

  • 2. New novobiocin analogues as antiproliferative agents in breast cancer cells and potential inhibitors of heat shock protein 90.
    Le Bras G, Radanyi C, Peyrat JF, Brion JD, Alami M, Marsaud V, Stella B, Renoir JM.
    J Med Chem; 2007 Nov 29; 50(24):6189-200. PubMed ID: 17979263
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors.
    Gunaherath GM, Marron MT, Wijeratne EM, Whitesell L, Gunatilaka AA.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5118-29. PubMed ID: 23859777
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and antiproliferative activity of novobiocin analogues as potential hsp90 inhibitors.
    Audisio D, Methy-Gonnot D, Radanyi C, Renoir JM, Denis S, Sauvage F, Vergnaud-Gauduchon J, Brion JD, Messaoudi S, Alami M.
    Eur J Med Chem; 2014 Aug 18; 83():498-507. PubMed ID: 24992077
    [Abstract] [Full Text] [Related]

  • 5. A novel, small molecule inhibitor of Hsc70/Hsp70 potentiates Hsp90 inhibitor induced apoptosis in HCT116 colon carcinoma cells.
    Massey AJ, Williamson DS, Browne H, Murray JB, Dokurno P, Shaw T, Macias AT, Daniels Z, Geoffroy S, Dopson M, Lavan P, Matassova N, Francis GL, Graham CJ, Parsons R, Wang Y, Padfield A, Comer M, Drysdale MJ, Wood M.
    Cancer Chemother Pharmacol; 2010 Aug 18; 66(3):535-45. PubMed ID: 20012863
    [Abstract] [Full Text] [Related]

  • 6. Hsp90 inhibitors identified from a library of novobiocin analogues.
    Yu XM, Shen G, Neckers L, Blake H, Holzbeierlein J, Cronk B, Blagg BS.
    J Am Chem Soc; 2005 Sep 21; 127(37):12778-9. PubMed ID: 16159253
    [Abstract] [Full Text] [Related]

  • 7. Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1H)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90.
    Larghi EL, Bruneau A, Sauvage F, Alami M, Vergnaud-Gauduchon J, Messaoudi S.
    Molecules; 2022 Jan 09; 27(2):. PubMed ID: 35056725
    [Abstract] [Full Text] [Related]

  • 8. Development of novobiocin analogues that manifest anti-proliferative activity against several cancer cell lines.
    Burlison JA, Avila C, Vielhauer G, Lubbers DJ, Holzbeierlein J, Blagg BS.
    J Org Chem; 2008 Mar 21; 73(6):2130-7. PubMed ID: 18293999
    [Abstract] [Full Text] [Related]

  • 9. Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead.
    Meli M, Pennati M, Curto M, Daidone MG, Plescia J, Toba S, Altieri DC, Zaffaroni N, Colombo G.
    J Med Chem; 2006 Dec 28; 49(26):7721-30. PubMed ID: 17181154
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and evaluation of coumermycin A1 analogues that inhibit the Hsp90 protein folding machinery.
    Burlison JA, Blagg BS.
    Org Lett; 2006 Oct 12; 8(21):4855-8. PubMed ID: 17020320
    [Abstract] [Full Text] [Related]

  • 11. Hsp90 inhibitors: small molecules that transform the Hsp90 protein folding machinery into a catalyst for protein degradation.
    Blagg BS, Kerr TD.
    Med Res Rev; 2006 May 12; 26(3):310-38. PubMed ID: 16385472
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90.
    Llauger L, He H, Kim J, Aguirre J, Rosen N, Peters U, Davies P, Chiosis G.
    J Med Chem; 2005 Apr 21; 48(8):2892-905. PubMed ID: 15828828
    [Abstract] [Full Text] [Related]

  • 13. Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90.
    Barta TE, Veal JM, Rice JW, Partridge JM, Fadden RP, Ma W, Jenks M, Geng L, Hanson GJ, Huang KH, Barabasz AF, Foley BE, Otto J, Hall SE.
    Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3517-21. PubMed ID: 18511277
    [Abstract] [Full Text] [Related]

  • 14. Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors.
    Musso L, Dallavalle S, Merlini L, Bava A, Nasini G, Penco S, Giannini G, Giommarelli C, De Cesare A, Zuco V, Vesci L, Pisano C, Castorina M, Milazzo F, Cervoni ML, Dal Piaz F, De Tommasi N, Zunino F.
    Bioorg Med Chem; 2010 Aug 15; 18(16):6031-43. PubMed ID: 20655237
    [Abstract] [Full Text] [Related]

  • 15. Targeting heat shock response to sensitize cancer cells to proteasome and Hsp90 inhibitors.
    Zaarur N, Gabai VL, Porco JA, Calderwood S, Sherman MY.
    Cancer Res; 2006 Feb 01; 66(3):1783-91. PubMed ID: 16452239
    [Abstract] [Full Text] [Related]

  • 16. Antiproliferative and apoptotic activities of tosylcyclonovobiocic acids as potent heat shock protein 90 inhibitors in human cancer cells.
    Radanyi C, Le Bras G, Marsaud V, Peyrat JF, Messaoudi S, Catelli MG, Brion JD, Alami M, Renoir JM.
    Cancer Lett; 2009 Feb 08; 274(1):88-94. PubMed ID: 18842335
    [Abstract] [Full Text] [Related]

  • 17. Targeting of multiple signalling pathways by heat shock protein 90 molecular chaperone inhibitors.
    Powers MV, Workman P.
    Endocr Relat Cancer; 2006 Dec 08; 13 Suppl 1():S125-35. PubMed ID: 17259553
    [Abstract] [Full Text] [Related]

  • 18. Efficacy of Hsp90 inhibition for induction of apoptosis and inhibition of growth in cervical carcinoma cells in vitro and in vivo.
    Schwock J, Pham NA, Cao MP, Hedley DW.
    Cancer Chemother Pharmacol; 2008 Apr 08; 61(4):669-81. PubMed ID: 17579866
    [Abstract] [Full Text] [Related]

  • 19. Derrubone, an inhibitor of the Hsp90 protein folding machinery.
    Hadden MK, Galam L, Gestwicki JE, Matts RL, Blagg BS.
    J Nat Prod; 2007 Dec 08; 70(12):2014-8. PubMed ID: 18020309
    [Abstract] [Full Text] [Related]

  • 20. Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors.
    Gyurkocza B, Plescia J, Raskett CM, Garlick DS, Lowry PA, Carter BZ, Andreeff M, Meli M, Colombo G, Altieri DC.
    J Natl Cancer Inst; 2006 Aug 02; 98(15):1068-77. PubMed ID: 16882944
    [Abstract] [Full Text] [Related]

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