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Journal Abstract Search

235 related items for PubMed ID: 21381897

  • 1. Effect of interferon-α2b on the expression of various drug-metabolizing enzymes and transporters in co-cultures of freshly prepared human primary hepatocytes.
    Chen C, Han YH, Yang Z, Rodrigues AD.
    Xenobiotica; 2011 Jun; 41(6):476-85. PubMed ID: 21381897
    [Abstract] [Full Text] [Related]

  • 2. Potential impact of steatosis on cytochrome P450 enzymes of human hepatocytes isolated from fatty liver grafts.
    Donato MT, Lahoz A, Jiménez N, Pérez G, Serralta A, Mir J, Castell JV, Gómez-Lechón MJ.
    Drug Metab Dispos; 2006 Sep; 34(9):1556-62. PubMed ID: 16763015
    [Abstract] [Full Text] [Related]

  • 3. Effects of bergamottin on human and monkey drug-metabolizing enzymes in primary cultured hepatocytes.
    Wen YH, Sahi J, Urda E, Kulkarni S, Rose K, Zheng X, Sinclair JF, Cai H, Strom SC, Kostrubsky VE.
    Drug Metab Dispos; 2002 Sep; 30(9):977-84. PubMed ID: 12167562
    [Abstract] [Full Text] [Related]

  • 4. Differential Effects of Sunitinib on the Expression Profiles of Xenobiotic-Metabolizing Enzymes and Transporters in Rat Liver and Kidneys.
    Korashy HM, Ansari MA, Maayah ZH, Imam F, Raish M, Attafi IM, Alharbi NO, Moraished BA.
    Basic Clin Pharmacol Toxicol; 2016 Aug; 119(2):173-83. PubMed ID: 26797788
    [Abstract] [Full Text] [Related]

  • 5. Effect of honokiol on the induction of drug-metabolizing enzymes in human hepatocytes.
    Cho YY, Jeong HU, Kim JH, Lee HS.
    Drug Des Devel Ther; 2014 Aug; 8():2137-45. PubMed ID: 25395831
    [Abstract] [Full Text] [Related]

  • 6. In vitro investigations into the roles of drug transporters and metabolizing enzymes in the disposition and drug interactions of dolutegravir, a HIV integrase inhibitor.
    Reese MJ, Savina PM, Generaux GT, Tracey H, Humphreys JE, Kanaoka E, Webster LO, Harmon KA, Clarke JD, Polli JW.
    Drug Metab Dispos; 2013 Feb; 41(2):353-61. PubMed ID: 23132334
    [Abstract] [Full Text] [Related]

  • 7. Proteomic analysis for the impact of hypercholesterolemia on expressions of hepatic drug transporters and metabolizing enzymes.
    Liu Y, Pu QH, Wu MJ, Yu C.
    Xenobiotica; 2016 Oct; 46(10):940-7. PubMed ID: 26887802
    [Abstract] [Full Text] [Related]

  • 8. Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture.
    Badolo L, Jensen B, Säll C, Norinder U, Kallunki P, Montanari D.
    Xenobiotica; 2015 Feb; 45(2):177-87. PubMed ID: 25183402
    [Abstract] [Full Text] [Related]

  • 9. Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes.
    Huang CS, Chen HW, Lin TY, Lin AH, Lii CK.
    J Ethnopharmacol; 2018 Apr 24; 216():18-25. PubMed ID: 29414119
    [Abstract] [Full Text] [Related]

  • 10. Efficient assessment of the utility of immortalized Fa2N-4 cells for cytochrome P450 (CYP) induction studies using multiplex quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and substrate cassette methodologies.
    Kenny JR, Chen L, McGinnity DF, Grime K, Shakesheff KM, Thomson B, Riley R.
    Xenobiotica; 2008 Dec 24; 38(12):1500-17. PubMed ID: 18989830
    [Abstract] [Full Text] [Related]

  • 11. Gene-specific effects of inflammatory cytokines on cytochrome P450 2C, 2B6 and 3A4 mRNA levels in human hepatocytes.
    Aitken AE, Morgan ET.
    Drug Metab Dispos; 2007 Sep 24; 35(9):1687-93. PubMed ID: 17576808
    [Abstract] [Full Text] [Related]

  • 12. The potential of Sutherlandia frutescens for herb-drug interaction.
    Fasinu PS, Gutmann H, Schiller H, James AD, Bouic PJ, Rosenkranz B.
    Drug Metab Dispos; 2013 Feb 24; 41(2):488-97. PubMed ID: 23209194
    [Abstract] [Full Text] [Related]

  • 13. Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT.
    Hevir N, Sinkovec J, Rižner TL.
    Mol Cell Endocrinol; 2011 Jan 01; 331(1):158-67. PubMed ID: 20887769
    [Abstract] [Full Text] [Related]

  • 14. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
    Dvorak Z, Modriansky M, Pichard-Garcia L, Balaguer P, Vilarem MJ, Ulrichová J, Maurel P, Pascussi JM.
    Mol Pharmacol; 2003 Jul 01; 64(1):160-9. PubMed ID: 12815172
    [Abstract] [Full Text] [Related]

  • 15. Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes.
    Xing J, Kirby BJ, Whittington D, Wan Y, Goodlett DR.
    Drug Metab Dispos; 2012 Sep 01; 40(9):1757-64. PubMed ID: 22679214
    [Abstract] [Full Text] [Related]

  • 16. Drug metabolizing enzyme and transporter protein profiles of hepatocytes derived from human embryonic and induced pluripotent stem cells.
    Ulvestad M, Nordell P, Asplund A, Rehnström M, Jacobsson S, Holmgren G, Davidson L, Brolén G, Edsbagge J, Björquist P, Küppers-Munther B, Andersson TB.
    Biochem Pharmacol; 2013 Sep 01; 86(5):691-702. PubMed ID: 23856292
    [Abstract] [Full Text] [Related]

  • 17. Substrate-dependent drug-drug interactions between gemfibrozil, fluvastatin and other organic anion-transporting peptide (OATP) substrates on OATP1B1, OATP2B1, and OATP1B3.
    Noé J, Portmann R, Brun ME, Funk C.
    Drug Metab Dispos; 2007 Aug 01; 35(8):1308-14. PubMed ID: 17470528
    [Abstract] [Full Text] [Related]

  • 18. Effect of silybin and its glycosides on the expression of cytochromes P450 1A2 and 3A4 in primary cultures of human hepatocytes.
    Kosina P, Maurel P, Ulrichová J, Dvorák Z.
    J Biochem Mol Toxicol; 2005 Aug 01; 19(3):149-53. PubMed ID: 15977188
    [Abstract] [Full Text] [Related]

  • 19. Modular bioreactor for primary human hepatocyte culture: medium flow stimulates expression and activity of detoxification genes.
    Vinci B, Duret C, Klieber S, Gerbal-Chaloin S, Sa-Cunha A, Laporte S, Suc B, Maurel P, Ahluwalia A, Daujat-Chavanieu M.
    Biotechnol J; 2011 May 01; 6(5):554-64. PubMed ID: 21259441
    [Abstract] [Full Text] [Related]

  • 20. Effect of bupropion on CYP2B6 and CYP3A4 catalytic activity, immunoreactive protein and mRNA levels in primary human hepatocytes: comparison with rifampicin.
    Hesse LM, Sakai Y, Vishnuvardhan D, Li AP, von Moltke LL, Greenblatt DJ.
    J Pharm Pharmacol; 2003 Sep 01; 55(9):1229-39. PubMed ID: 14604466
    [Abstract] [Full Text] [Related]

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