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278 related items for PubMed ID: 21383964
1. AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants. Ruiz JF, Gómez-González B, Aguilera A. PLoS Genet; 2011 Feb; 7(2):e1002009. PubMed ID: 21383964 [Abstract] [Full Text] [Related]
2. DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells. So CC, Martin A. PLoS Genet; 2019 Apr; 15(4):e1008101. PubMed ID: 30946744 [Abstract] [Full Text] [Related]
3. Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes. Hu J, Tepsuporn S, Meyers RM, Gostissa M, Alt FW. Proc Natl Acad Sci U S A; 2014 Jul 15; 111(28):10269-74. PubMed ID: 24982162 [Abstract] [Full Text] [Related]
4. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Robbiani DF, Bothmer A, Callen E, Reina-San-Martin B, Dorsett Y, Difilippantonio S, Bolland DJ, Chen HT, Corcoran AE, Nussenzweig A, Nussenzweig MC. Cell; 2008 Dec 12; 135(6):1028-38. PubMed ID: 19070574 [Abstract] [Full Text] [Related]
5. AID- and Ung-dependent generation of staggered double-strand DNA breaks in immunoglobulin class switch DNA recombination: a post-cleavage role for AID. Zan H, Casali P. Mol Immunol; 2008 Nov 12; 46(1):45-61. PubMed ID: 18760480 [Abstract] [Full Text] [Related]
6. Endonuclease G plays a role in immunoglobulin class switch DNA recombination by introducing double-strand breaks in switch regions. Zan H, Zhang J, Al-Qahtani A, Pone EJ, White CA, Lee D, Yel L, Mai T, Casali P. Mol Immunol; 2011 Jan 12; 48(4):610-22. PubMed ID: 21111482 [Abstract] [Full Text] [Related]
8. Individual substitution mutations in the AID C terminus that ablate IgH class switch recombination. Kadungure T, Ucher AJ, Linehan EK, Schrader CE, Stavnezer J. PLoS One; 2015 Jan 12; 10(8):e0134397. PubMed ID: 26267846 [Abstract] [Full Text] [Related]
9. Mechanisms promoting translocations in editing and switching peripheral B cells. Wang JH, Gostissa M, Yan CT, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann DR, Zarrin AA, Rajewsky K, Nussenzweig A, Alt FW. Nature; 2009 Jul 09; 460(7252):231-6. PubMed ID: 19587764 [Abstract] [Full Text] [Related]
10. Activation-induced cytidine deaminase action is strongly stimulated by mutations of the THO complex. Gómez-González B, Aguilera A. Proc Natl Acad Sci U S A; 2007 May 15; 104(20):8409-14. PubMed ID: 17488823 [Abstract] [Full Text] [Related]
11. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70. Boboila C, Jankovic M, Yan CT, Wang JH, Wesemann DR, Zhang T, Fazeli A, Feldman L, Nussenzweig A, Nussenzweig M, Alt FW. Proc Natl Acad Sci U S A; 2010 Feb 16; 107(7):3034-9. PubMed ID: 20133803 [Abstract] [Full Text] [Related]
12. Antibody class switching mediated by yeast endonuclease-generated DNA breaks. Zarrin AA, Del Vecchio C, Tseng E, Gleason M, Zarin P, Tian M, Alt FW. Science; 2007 Jan 19; 315(5810):377-81. PubMed ID: 17170253 [Abstract] [Full Text] [Related]
14. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Nature; 2006 Mar 02; 440(7080):105-9. PubMed ID: 16400328 [Abstract] [Full Text] [Related]
15. C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion. Sabouri S, Kobayashi M, Begum NA, Xu J, Hirota K, Honjo T. Proc Natl Acad Sci U S A; 2014 Feb 11; 111(6):2253-8. PubMed ID: 24469810 [Abstract] [Full Text] [Related]
16. Histone methyltransferase MMSET promotes AID-mediated DNA breaks at the donor switch region during class switch recombination. Nguyen HV, Dong J, Panchakshari RA, Kumar V, Alt FW, Bories JC. Proc Natl Acad Sci U S A; 2017 Dec 05; 114(49):E10560-E10567. PubMed ID: 29158395 [Abstract] [Full Text] [Related]
17. Evaluation of potential role of R-loop and G-quadruplex DNA in the fragility of c-MYC during chromosomal translocation associated with Burkitt's lymphoma. Kumari N, Das K, Sharma S, Dahal S, Desai SS, Roy U, Sharma A, Manjunath M, Gopalakrishnan V, Retheesh ST, Javadekar SM, Choudhary B, Raghavan SC. J Biol Chem; 2023 Dec 05; 299(12):105431. PubMed ID: 37926284 [Abstract] [Full Text] [Related]
18. Single-strand DNA breaks in Ig class switch recombination that depend on UNG but not AID. Arudchandran A, Bernstein RM, Max EE. Int Immunol; 2008 Nov 05; 20(11):1381-93. PubMed ID: 18794203 [Abstract] [Full Text] [Related]
20. AID and Reactive Oxygen Species Can Induce DNA Breaks within Human Chromosomal Translocation Fragile Zones. Pannunzio NR, Lieber MR. Mol Cell; 2017 Dec 07; 68(5):901-912.e3. PubMed ID: 29220655 [Abstract] [Full Text] [Related] Page: [Next] [New Search]