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336 related items for PubMed ID: 21384195

  • 1. Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy.
    Vig PJ, Hearst S, Shao Q, Lopez ME, Murphy HA, Safaya E.
    Cerebellum; 2011 Jun; 10(2):254-66. PubMed ID: 21384195
    [Abstract] [Full Text] [Related]

  • 2. Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation.
    Hearst SM, Lopez ME, Shao Q, Liu Y, Vig PJ.
    J Neurochem; 2010 Aug; 114(3):706-16. PubMed ID: 20477910
    [Abstract] [Full Text] [Related]

  • 3. Bergmann glial S100B activates myo-inositol monophosphatase 1 and Co-localizes to purkinje cell vacuoles in SCA1 transgenic mice.
    Vig PJ, Shao Q, Subramony SH, Lopez ME, Safaya E.
    Cerebellum; 2009 Sep; 8(3):231-44. PubMed ID: 19593677
    [Abstract] [Full Text] [Related]

  • 4. Focused cerebellar laser light induced hyperthermia improves symptoms and pathology of polyglutamine disease SCA1 in a mouse model.
    Hearst SM, Shao Q, Lopez M, Raucher D, Vig PJ.
    Cerebellum; 2014 Oct; 13(5):596-606. PubMed ID: 24930030
    [Abstract] [Full Text] [Related]

  • 5. Purkinje cell ataxin-1 modulates climbing fiber synaptic input in developing and adult mouse cerebellum.
    Ebner BA, Ingram MA, Barnes JA, Duvick LA, Frisch JL, Clark HB, Zoghbi HY, Ebner TJ, Orr HT.
    J Neurosci; 2013 Mar 27; 33(13):5806-20. PubMed ID: 23536093
    [Abstract] [Full Text] [Related]

  • 6. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.
    Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, Zoghbi HY, Clark HB, Orr HT.
    Neuron; 2003 May 08; 38(3):375-87. PubMed ID: 12741986
    [Abstract] [Full Text] [Related]

  • 7. Relationship between ataxin-1 nuclear inclusions and Purkinje cell specific proteins in SCA-1 transgenic mice.
    Vig PJ, Subramony SH, Qin Z, McDaniel DO, Fratkin JD.
    J Neurol Sci; 2000 Mar 15; 174(2):100-10. PubMed ID: 10727695
    [Abstract] [Full Text] [Related]

  • 8. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
    Cummings CJ, Orr HT, Zoghbi HY.
    Philos Trans R Soc Lond B Biol Sci; 1999 Jun 29; 354(1386):1079-81. PubMed ID: 10434309
    [Abstract] [Full Text] [Related]

  • 9. The design and delivery of a thermally responsive peptide to inhibit S100B-mediated neurodegeneration.
    Hearst SM, Walker LR, Shao Q, Lopez M, Raucher D, Vig PJ.
    Neuroscience; 2011 Dec 01; 197():369-80. PubMed ID: 21958864
    [Abstract] [Full Text] [Related]

  • 10. Recovery from polyglutamine-induced neurodegeneration in conditional SCA1 transgenic mice.
    Zu T, Duvick LA, Kaytor MD, Berlinger MS, Zoghbi HY, Clark HB, Orr HT.
    J Neurosci; 2004 Oct 06; 24(40):8853-61. PubMed ID: 15470152
    [Abstract] [Full Text] [Related]

  • 11. Decreased expression of glutamate transporter GLAST in Bergmann glia is associated with the loss of Purkinje neurons in the spinocerebellar ataxia type 1.
    Cvetanovic M.
    Cerebellum; 2015 Feb 06; 14(1):8-11. PubMed ID: 25255716
    [Abstract] [Full Text] [Related]

  • 12. SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.
    Duvick L, Barnes J, Ebner B, Agrawal S, Andresen M, Lim J, Giesler GJ, Zoghbi HY, Orr HT.
    Neuron; 2010 Sep 23; 67(6):929-35. PubMed ID: 20869591
    [Abstract] [Full Text] [Related]

  • 13. Suppression of calbindin-D28k expression exacerbates SCA1 phenotype in a disease mouse model.
    Vig PJ, Wei J, Shao Q, Lopez ME, Halperin R, Gerber J.
    Cerebellum; 2012 Sep 23; 11(3):718-32. PubMed ID: 22076800
    [Abstract] [Full Text] [Related]

  • 14. USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.
    Hong S, Kim SJ, Ka S, Choi I, Kang S.
    Mol Cell Neurosci; 2002 Jun 23; 20(2):298-306. PubMed ID: 12093161
    [Abstract] [Full Text] [Related]

  • 15. SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis.
    Orr HT.
    Prog Neurobiol; 2012 Dec 23; 99(3):179-85. PubMed ID: 22531670
    [Abstract] [Full Text] [Related]

  • 16. Intranasal administration of IGF-I improves behavior and Purkinje cell pathology in SCA1 mice.
    Vig PJ, Subramony SH, D'Souza DR, Wei J, Lopez ME.
    Brain Res Bull; 2006 May 15; 69(5):573-9. PubMed ID: 16647585
    [Abstract] [Full Text] [Related]

  • 17. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.
    Cummings CJ, Reinstein E, Sun Y, Antalffy B, Jiang Y, Ciechanover A, Orr HT, Beaudet AL, Zoghbi HY.
    Neuron; 1999 Dec 15; 24(4):879-92. PubMed ID: 10624951
    [Abstract] [Full Text] [Related]

  • 18. A novel function of Ataxin-1 in the modulation of PP2A activity is dysregulated in the spinocerebellar ataxia type 1.
    Sánchez I, Piñol P, Corral-Juan M, Pandolfo M, Matilla-Dueñas A.
    Hum Mol Genet; 2013 Sep 01; 22(17):3425-37. PubMed ID: 23630944
    [Abstract] [Full Text] [Related]

  • 19. Altered trafficking of membrane proteins in purkinje cells of SCA1 transgenic mice.
    Skinner PJ, Vierra-Green CA, Clark HB, Zoghbi HY, Orr HT.
    Am J Pathol; 2001 Sep 01; 159(3):905-13. PubMed ID: 11549583
    [Abstract] [Full Text] [Related]

  • 20. Glial S100B Positive Vacuoles In Purkinje Cells: Earliest Morphological Abnormality In SCA1 Transgenic Mice.
    Vig PJ, Lopez ME, Wei J, D'Souza DR, Subramony S, Henegar J, Fratkin JD.
    J Neurol Sci Turk; 2006 Sep 01; 23(3):166-174. PubMed ID: 18176630
    [Abstract] [Full Text] [Related]

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