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Journal Abstract Search

132 related items for PubMed ID: 21385578

  • 1. Disease-modifying effect of ASP3258, a novel phosphodiesterase type 4 inhibitor, on subchronic cigarette smoke exposure-induced lung injury in guinea pigs.
    Kubo S, Kobayashi M, Iwata M, Takahashi K, Miyata K, Shimizu Y.
    Eur J Pharmacol; 2011 May 20; 659(1):79-84. PubMed ID: 21385578
    [Abstract] [Full Text] [Related]

  • 2. Anti-neutrophilic inflammatory activity of ASP3258, a novel phosphodiesterase type 4 inhibitor.
    Kubo S, Kobayashi M, Iwata M, Miyata K, Takahashi K, Shimizu Y.
    Int Immunopharmacol; 2012 Jan 20; 12(1):59-63. PubMed ID: 22041526
    [Abstract] [Full Text] [Related]

  • 3. Anti-asthmatic effect of ASP3258, a novel phosphodiesterase 4 inhibitor.
    Kobayashi M, Kubo S, Hirano Y, Kobayashi S, Takahashi K, Shimizu Y.
    Int Immunopharmacol; 2012 Jan 20; 12(1):50-8. PubMed ID: 22036845
    [Abstract] [Full Text] [Related]

  • 4. ASP3258, an orally active potent phosphodiesterase 4 inhibitor with low emetic activity.
    Kobayashi M, Kubo S, Iwata M, Ohtsu Y, Takahashi K, Shimizu Y.
    Int Immunopharmacol; 2011 Jun 20; 11(6):732-9. PubMed ID: 21315169
    [Abstract] [Full Text] [Related]

  • 5. Therapeutic potential of ASP3258, a selective phosphodiesterase 4 inhibitor, on chronic eosinophilic airway inflammation.
    Kobayashi M, Kubo S, Shiraki K, Iwata M, Hirano Y, Ohtsu Y, Takahashi K, Shimizu Y.
    Pharmacology; 2012 Jun 20; 90(3-4):223-32. PubMed ID: 23038661
    [Abstract] [Full Text] [Related]

  • 6. Cigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in Mice.
    Seimetz M, Parajuli N, Pichl A, Bednorz M, Ghofrani HA, Schermuly RT, Seeger W, Grimminger F, Weissmann N.
    PLoS One; 2015 Jun 20; 10(6):e0129327. PubMed ID: 26058042
    [Abstract] [Full Text] [Related]

  • 7. Cytokine and chemokine expression in cigarette smoke-induced lung injury in guinea pigs.
    Kubo S, Kobayashi M, Masunaga Y, Ishii H, Hirano Y, Takahashi K, Shimizu Y.
    Eur Respir J; 2005 Dec 20; 26(6):993-1001. PubMed ID: 16319327
    [Abstract] [Full Text] [Related]

  • 8. Oxidative stress and lung injury induced by short-term exposure to wood smoke in guinea pigs.
    Ramos C, Pedraza-Chaverri J, Becerril C, Cisneros J, González-Ávila G, Rivera-Rosales R, Sommer B, Medina-Campos ON, Montaño M.
    Toxicol Mech Methods; 2013 Nov 20; 23(9):711-22. PubMed ID: 24024665
    [Abstract] [Full Text] [Related]

  • 9. The preclinical pharmacology of roflumilast--a selective, oral phosphodiesterase 4 inhibitor in development for chronic obstructive pulmonary disease.
    Hatzelmann A, Morcillo EJ, Lungarella G, Adnot S, Sanjar S, Beume R, Schudt C, Tenor H.
    Pulm Pharmacol Ther; 2010 Aug 20; 23(4):235-56. PubMed ID: 20381629
    [Abstract] [Full Text] [Related]

  • 10. Ghrelin ameliorates catabolic conditions and respiratory dysfunction in a chronic obstructive pulmonary disease model of chronic cigarette smoke-exposed rats.
    Kamiide Y, Inomata N, Furuya M, Yada T.
    Eur J Pharmacol; 2015 May 15; 755():88-94. PubMed ID: 25771457
    [Abstract] [Full Text] [Related]

  • 11. Pulmonary inflammatory reaction and structural changes induced by cigarette smoke exposure in the Guinea pig.
    Domínguez-Fandos D, Peinado VI, Puig-Pey R, Ferrer E, Musri MM, Ramírez J, Barberà JA.
    COPD; 2012 Aug 15; 9(5):473-84. PubMed ID: 22708688
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological Profile of GPD-1116, an Inhibitor of Phosphodiesterase 4.
    Nose T, Kondo M, Shimizu M, Hamura H, Yamaguchi Y, Sekine T, Ishitani K.
    Biol Pharm Bull; 2016 Aug 15; 39(5):689-98. PubMed ID: 27150141
    [Abstract] [Full Text] [Related]

  • 13. Phosphodiesterase 4 inhibitor GPD-1116 markedly attenuates the development of cigarette smoke-induced emphysema in senescence-accelerated mice P1 strain.
    Mori H, Nose T, Ishitani K, Kasagi S, Souma S, Akiyoshi T, Kodama Y, Mori T, Kondo M, Sasaki S, Iwase A, Takahashi K, Fukuchi Y, Seyama K.
    Am J Physiol Lung Cell Mol Physiol; 2008 Feb 15; 294(2):L196-204. PubMed ID: 17993591
    [Abstract] [Full Text] [Related]

  • 14. The phosphodiesterase 4 inhibitor rolipram protects against cigarette smoke extract-induced apoptosis in human lung fibroblasts.
    Park JW, Ryter SW, Kyung SY, Lee SP, Jeong SH.
    Eur J Pharmacol; 2013 Apr 15; 706(1-3):76-83. PubMed ID: 23499692
    [Abstract] [Full Text] [Related]

  • 15. Effects of aclidinium bromide in a cigarette smoke-exposed Guinea pig model of chronic obstructive pulmonary disease.
    Domínguez-Fandos D, Ferrer E, Puig-Pey R, Carreño C, Prats N, Aparici M, Musri MM, Gavaldà A, Peinado VI, Miralpeix M, Barberà JA.
    Am J Respir Cell Mol Biol; 2014 Feb 15; 50(2):337-46. PubMed ID: 24032416
    [Abstract] [Full Text] [Related]

  • 16. Pulmonary cell infiltration after chronic exposure to (1-->3)-beta-D-glucan and cigarette smoke.
    Sjöstrand M, Rylander R.
    Inflamm Res; 1997 Mar 15; 46(3):93-7. PubMed ID: 9098721
    [Abstract] [Full Text] [Related]

  • 17. TAS-203, an oral phosphodiesterase 4 inhibitor, exerts anti-inflammatory activities in a rat airway inflammation model.
    Demizu S, Asaka N, Kawahara H, Sasaki E.
    Eur J Pharmacol; 2019 Apr 15; 849():22-29. PubMed ID: 30716315
    [Abstract] [Full Text] [Related]

  • 18. Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.
    Bozinovski S, Seow HJ, Chan SP, Anthony D, McQualter J, Hansen M, Jenkins BJ, Anderson GP, Vlahos R.
    Clin Sci (Lond); 2015 Nov 15; 129(9):785-96. PubMed ID: 26201093
    [Abstract] [Full Text] [Related]

  • 19. Anti-malarial drug artesunate protects against cigarette smoke-induced lung injury in mice.
    Ng DS, Liao W, Tan WS, Chan TK, Loh XY, Wong WS.
    Phytomedicine; 2014 Oct 15; 21(12):1638-44. PubMed ID: 25442271
    [Abstract] [Full Text] [Related]

  • 20. Protective effects of liquiritin apioside on cigarette smoke-induced lung epithelial cell injury.
    Guan Y, Li FF, Hong L, Yan XF, Tan GL, He JS, Dong XW, Bao MJ, Xie QM.
    Fundam Clin Pharmacol; 2012 Aug 15; 26(4):473-83. PubMed ID: 21631586
    [Abstract] [Full Text] [Related]

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