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157 related items for PubMed ID: 21385937

  • 1. Dynamic regulation of PDX-1 and FoxO1 expression by FoxA2 in dexamethasone-induced pancreatic β-cells dysfunction.
    Chen F, Zhu Y, Tang X, Sun Y, Jia W, Sun Y, Han X.
    Endocrinology; 2011 May; 152(5):1779-88. PubMed ID: 21385937
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of forkhead box O1 protects pancreatic beta-cells against dexamethasone-induced dysfunction.
    Zhang X, Yong W, Lv J, Zhu Y, Zhang J, Chen F, Zhang R, Yang T, Sun Y, Han X.
    Endocrinology; 2009 Sep; 150(9):4065-73. PubMed ID: 19443572
    [Abstract] [Full Text] [Related]

  • 3. Transcription factor Ets-1 links glucotoxicity to pancreatic beta cell dysfunction through inhibiting PDX-1 expression in rodent models.
    Chen F, Sha M, Wang Y, Wu T, Shan W, Liu J, Zhou W, Zhu Y, Sun Y, Shi Y, Bleich D, Han X.
    Diabetologia; 2016 Feb; 59(2):316-24. PubMed ID: 26564177
    [Abstract] [Full Text] [Related]

  • 4. Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
    Meng Z, Lv J, Luo Y, Lin Y, Zhu Y, Nie J, Yang T, Sun Y, Han X.
    Endocrinology; 2009 Dec; 150(12):5284-93. PubMed ID: 19837872
    [Abstract] [Full Text] [Related]

  • 5. PRMT1 promotes glucose toxicity-induced β cell dysfunction by regulating the nucleo-cytoplasmic trafficking of PDX-1 in a FOXO1-dependent manner in INS-1 cells.
    Lv L, Chen H, Sun J, Lu D, Chen C, Liu D.
    Endocrine; 2015 Aug; 49(3):669-82. PubMed ID: 25874535
    [Abstract] [Full Text] [Related]

  • 6. FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site.
    Raum JC, Gerrish K, Artner I, Henderson E, Guo M, Sussel L, Schisler JC, Newgard CB, Stein R.
    Mol Cell Biol; 2006 Aug; 26(15):5735-43. PubMed ID: 16847327
    [Abstract] [Full Text] [Related]

  • 7. AGEs decrease insulin synthesis in pancreatic β-cell by repressing Pdx-1 protein expression at the post-translational level.
    Shu T, Zhu Y, Wang H, Lin Y, Ma Z, Han X.
    PLoS One; 2011 Apr 18; 6(4):e18782. PubMed ID: 21533167
    [Abstract] [Full Text] [Related]

  • 8. Circadian regulation of intestinal lipid absorption by apolipoprotein AIV involves forkhead transcription factors A2 and O1 and microsomal triglyceride transfer protein.
    Pan X, Munshi MK, Iqbal J, Queiroz J, Sirwi AA, Shah S, Younus A, Hussain MM.
    J Biol Chem; 2013 Jul 12; 288(28):20464-76. PubMed ID: 23729668
    [Abstract] [Full Text] [Related]

  • 9. Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.
    Shao S, Nie M, Chen C, Chen X, Zhang M, Yuan G, Yu X, Yang Y.
    J Cell Biochem; 2014 Jun 12; 115(6):1166-75. PubMed ID: 24415347
    [Abstract] [Full Text] [Related]

  • 10. Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).
    Meur G, Qian Q, da Silva Xavier G, Pullen TJ, Tsuboi T, McKinnon C, Fletcher L, Tavaré JM, Hughes S, Johnson P, Rutter GA.
    J Biol Chem; 2011 Apr 15; 286(15):13647-56. PubMed ID: 21335550
    [Abstract] [Full Text] [Related]

  • 11. Effect of nicotinamide mononucleotide on insulin secretion and gene expressions of PDX-1 and FoxO1 in RIN-m5f cells.
    Sheng F, Ren X, Dai X, Xu X, Dong M, Pei Q, Qu J, Zhou Z, Zhou H, Liu Z.
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2011 Oct 15; 36(10):958-63. PubMed ID: 22086006
    [Abstract] [Full Text] [Related]

  • 12. Advanced glycation end-products affect transcription factors regulating insulin gene expression.
    Puddu A, Storace D, Odetti P, Viviani GL.
    Biochem Biophys Res Commun; 2010 Apr 23; 395(1):122-5. PubMed ID: 20353756
    [Abstract] [Full Text] [Related]

  • 13. B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic β-cells.
    Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD.
    Exp Mol Med; 2013 May 24; 45(5):e25. PubMed ID: 23703573
    [Abstract] [Full Text] [Related]

  • 14. Activation of SIRT1 protects pancreatic β-cells against palmitate-induced dysfunction.
    Wu L, Zhou L, Lu Y, Zhang J, Jian F, Liu Y, Li F, Li W, Wang X, Li G.
    Biochim Biophys Acta; 2012 Nov 24; 1822(11):1815-25. PubMed ID: 22968147
    [Abstract] [Full Text] [Related]

  • 15. Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.
    Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C.
    J Biol Chem; 2014 Nov 21; 289(47):32798-810. PubMed ID: 25271154
    [Abstract] [Full Text] [Related]

  • 16. Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro.
    Kaiser G, Gerst F, Michael D, Berchtold S, Friedrich B, Strutz-Seebohm N, Lang F, Häring HU, Ullrich S.
    Diabetologia; 2013 Jul 21; 56(7):1587-95. PubMed ID: 23435785
    [Abstract] [Full Text] [Related]

  • 17. Pdx-1 regulation of the INGAP promoter involves sequestration of NeuroD into a non-DNA-binding complex.
    Taylor-Fishwick DA, Shi W, Hughes L, Vinik A.
    Pancreas; 2010 Jan 21; 39(1):64-70. PubMed ID: 19770784
    [Abstract] [Full Text] [Related]

  • 18. Forkhead box transcription factor regulation and lipid accumulation by hepatitis C virus.
    Bose SK, Kim H, Meyer K, Wolins N, Davidson NO, Ray R.
    J Virol; 2014 Apr 21; 88(8):4195-203. PubMed ID: 24478438
    [Abstract] [Full Text] [Related]

  • 19. The interplay of prolactin and the glucocorticoids in the regulation of beta-cell gene expression, fatty acid oxidation, and glucose-stimulated insulin secretion: implications for carbohydrate metabolism in pregnancy.
    Arumugam R, Horowitz E, Lu D, Collier JJ, Ronnebaum S, Fleenor D, Freemark M.
    Endocrinology; 2008 Nov 21; 149(11):5401-14. PubMed ID: 18599550
    [Abstract] [Full Text] [Related]

  • 20. FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.
    Kibbe C, Chen J, Xu G, Jing G, Shalev A.
    J Biol Chem; 2013 Aug 09; 288(32):23194-202. PubMed ID: 23803610
    [Abstract] [Full Text] [Related]

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