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Journal Abstract Search

200 related items for PubMed ID: 2138609

  • 1. Substitution of arginine for Leu444 in the reactive site of heparin cofactor II enhances the rate of thrombin inhibition.
    Derechin VM, Blinder MA, Tollefsen DM.
    J Biol Chem; 1990 Apr 05; 265(10):5623-8. PubMed ID: 2138609
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  • 2. The N-terminal acidic domain of heparin cofactor II mediates the inhibition of alpha-thrombin in the presence of glycosaminoglycans.
    Van Deerlin VM, Tollefsen DM.
    J Biol Chem; 1991 Oct 25; 266(30):20223-31. PubMed ID: 1939083
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  • 3. Site-directed mutagenesis of arginine 103 and lysine 185 in the proposed glycosaminoglycan-binding site of heparin cofactor II.
    Blinder MA, Tollefsen DM.
    J Biol Chem; 1990 Jan 05; 265(1):286-91. PubMed ID: 2104620
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  • 6. Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II.
    Han JH, Van Deerlin VM, Tollefsen DM.
    J Biol Chem; 1997 Mar 28; 272(13):8243-9. PubMed ID: 9079643
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  • 7. Heparin promotes proteolytic inactivation by thrombin of a reactive site mutant (L444R) of recombinant heparin cofactor II.
    Ciaccia AV, Willemze AJ, Church FC.
    J Biol Chem; 1997 Jan 10; 272(2):888-93. PubMed ID: 8995378
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  • 8. Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote intramolecular interactions during glycosaminoglycan binding and thrombin inhibition.
    Mitchell JW, Church FC.
    J Biol Chem; 2002 May 31; 277(22):19823-30. PubMed ID: 11856753
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  • 10. Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity.
    Sheehan JP, Wu Q, Tollefsen DM, Sadler JE.
    J Biol Chem; 1993 Feb 15; 268(5):3639-45. PubMed ID: 8429040
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  • 12. Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition.
    Filion ML, Bhakta V, Nguyen LH, Liaw PS, Sheffield WP.
    Biochemistry; 2004 Nov 23; 43(46):14864-72. PubMed ID: 15544357
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  • 18. The protease specificity of heparin cofactor II. Inhibition of thrombin generated during coagulation.
    Parker KA, Tollefsen DM.
    J Biol Chem; 1985 Mar 25; 260(6):3501-5. PubMed ID: 3838315
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  • 19. Heparin cofactor II is regulated allosterically and not primarily by template effects. Studies with mutant thrombins and glycosaminoglycans.
    Sheehan JP, Tollefsen DM, Sadler JE.
    J Biol Chem; 1994 Dec 30; 269(52):32747-51. PubMed ID: 7806495
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  • 20. Mechanism of thrombin inhibition by heparin cofactor II and antithrombin in the presence of the ray (Raja radula) skin dermatan sulfate.
    Ben Mansour M, Dhahri M, Vénisse L, Jandrot-Perrus M, Chaubet F, Maaroufi RM.
    Thromb Res; 2009 Apr 30; 123(6):902-8. PubMed ID: 19046760
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