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Journal Abstract Search


142 related items for PubMed ID: 21386766

  • 1. Effect of ruboxistaurin (RBX) On visual acuity decline over a 6-year period with cessation and reinstitution of therapy: results of an open-label extension of the Protein Kinase C Diabetic Retinopathy Study 2 (PKC-DRS2).
    Sheetz MJ, Aiello LP, Shahri N, Davis MD, Kles KA, Danis RP, Mbdv Study Group.
    Retina; 2011 Jun; 31(6):1053-9. PubMed ID: 21386766
    [Abstract] [Full Text] [Related]

  • 2. Oral protein kinase c β inhibition using ruboxistaurin: efficacy, safety, and causes of vision loss among 813 patients (1,392 eyes) with diabetic retinopathy in the Protein Kinase C β Inhibitor-Diabetic Retinopathy Study and the Protein Kinase C β Inhibitor-Diabetic Retinopathy Study 2.
    Aiello LP, Vignati L, Sheetz MJ, Zhi X, Girach A, Davis MD, Wolka AM, Shahri N, Milton RC, PKC-DRS and PKC-DRS2 Study Groups.
    Retina; 2011 Nov; 31(10):2084-94. PubMed ID: 21862954
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  • 3. The effect of the oral PKC β inhibitor ruboxistaurin on vision loss in two phase 3 studies.
    Sheetz MJ, Aiello LP, Davis MD, Danis R, Bek T, Cunha-Vaz J, Shahri N, Berg PH, MBDL and MBCU Study Groups.
    Invest Ophthalmol Vis Sci; 2013 Mar 11; 54(3):1750-7. PubMed ID: 23404115
    [Abstract] [Full Text] [Related]

  • 4. Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy.
    PKC-DRS2 GroupBeetham Eye Institute, Joslin Diabetes Center, 1 Joslin Place, Boston, MA 02215, USA. LPAiello@Joslin.Harvard.edu, Aiello LP, Davis MD, Girach A, Kles KA, Milton RC, Sheetz MJ, Vignati L, Zhi XE.
    Ophthalmology; 2006 Dec 11; 113(12):2221-30. PubMed ID: 16989901
    [Abstract] [Full Text] [Related]

  • 5. Sustained moderate visual loss as a predictive end point for visual loss in non-proliferative diabetic retinopathy.
    Girach A, Aiello LP, Milton RC, Davis MD, Danis RP, Zhi X, Sheetz MJ, Vignati L, PKC-DRS2 Study Group.
    Eye (Lond); 2009 Jan 11; 23(1):209-14. PubMed ID: 18989348
    [Abstract] [Full Text] [Related]

  • 6. Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema.
    Davis MD, Sheetz MJ, Aiello LP, Milton RC, Danis RP, Zhi X, Girach A, Jimenez MC, Vignati L, PKC-DRS2 Study Group.
    Invest Ophthalmol Vis Sci; 2009 Jan 11; 50(1):1-4. PubMed ID: 18708615
    [Abstract] [Full Text] [Related]

  • 7. The effect of ruboxistaurin on visual loss in patients with moderately severe to very severe nonproliferative diabetic retinopathy: initial results of the Protein Kinase C beta Inhibitor Diabetic Retinopathy Study (PKC-DRS) multicenter randomized clinical trial.
    PKC-DRS Study Group.
    Diabetes; 2005 Jul 11; 54(7):2188-97. PubMed ID: 15983221
    [Abstract] [Full Text] [Related]

  • 8. Treatment of symptomatic diabetic peripheral neuropathy with the protein kinase C beta-inhibitor ruboxistaurin mesylate during a 1-year, randomized, placebo-controlled, double-blind clinical trial.
    Vinik AI, Bril V, Kempler P, Litchy WJ, Tesfaye S, Price KL, Bastyr EJ, MBBQ Study Group.
    Clin Ther; 2005 Aug 11; 27(8):1164-80. PubMed ID: 16199243
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  • 10. Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema.
    Sahu AK, Majji AB.
    Invest Ophthalmol Vis Sci; 2010 Dec 11; 51(12):6890; author reply 6890-1. PubMed ID: 21123772
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  • 17. A PKC-beta inhibitor protects against cardiac microvascular ischemia reperfusion injury in diabetic rats.
    Wei L, Sun D, Yin Z, Yuan Y, Hwang A, Zhang Y, Si R, Zhang R, Guo W, Cao F, Wang H.
    Apoptosis; 2010 Apr 11; 15(4):488-98. PubMed ID: 20044781
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  • 18. Effect of ruboxistaurin on blood-retinal barrier permeability in relation to severity of leakage in diabetic macular edema.
    Strøm C, Sander B, Klemp K, Aiello LP, Lund-Andersen H, Larsen M.
    Invest Ophthalmol Vis Sci; 2005 Oct 11; 46(10):3855-8. PubMed ID: 16186374
    [Abstract] [Full Text] [Related]

  • 19. Ruboxistaurin for diabetic retinopathy.
    Gardner TW, Antonetti DA.
    Ophthalmology; 2006 Dec 11; 113(12):2135-6. PubMed ID: 17157131
    [No Abstract] [Full Text] [Related]

  • 20. PKC inhibition and diabetic microvascular complications.
    Clarke M, Dodson PM.
    Best Pract Res Clin Endocrinol Metab; 2007 Dec 11; 21(4):573-86. PubMed ID: 18054736
    [Abstract] [Full Text] [Related]


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