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3. Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore. Dong M, Lam PC, Pinon DI, Hosohata K, Orry A, Sexton PM, Abagyan R, Miller LJ. J Biol Chem; 2011 Jul 08; 286(27):23888-99. PubMed ID: 21566140 [Abstract] [Full Text] [Related]
4. Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist. Dong M, Te JA, Xu X, Wang J, Pinon DI, Storjohann L, Bordner AJ, Miller LJ. Biochemistry; 2011 Sep 27; 50(38):8181-92. PubMed ID: 21851058 [Abstract] [Full Text] [Related]
5. Mapping spatial approximations between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping. Dong M, Xu X, Ball AM, Makhoul JA, Lam PC, Pinon DI, Orry A, Sexton PM, Abagyan R, Miller LJ. FASEB J; 2012 Dec 27; 26(12):5092-105. PubMed ID: 22964305 [Abstract] [Full Text] [Related]
8. Insights into the impact of phenolic residue incorporation at each position along secretin for receptor binding and biological activity. Dong M, Pinon DI, Miller LJ. Regul Pept; 2013 Jan 10; 180():5-11. PubMed ID: 23142313 [Abstract] [Full Text] [Related]
11. Identification of two pairs of spatially approximated residues within the carboxyl terminus of secretin and its receptor. Dong M, Asmann YW, Zang M, Pinon DI, Miller LJ. J Biol Chem; 2000 Aug 25; 275(34):26032-9. PubMed ID: 10859300 [Abstract] [Full Text] [Related]
13. Spatial approximation between two residues in the mid-region of secretin and the amino terminus of its receptor. Incorporation of seven sets of such constraints into a three-dimensional model of the agonist-bound secretin receptor. Dong M, Li Z, Zang M, Pinon DI, Lybrand TP, Miller LJ. J Biol Chem; 2003 Nov 28; 278(48):48300-12. PubMed ID: 14500709 [Abstract] [Full Text] [Related]
16. Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor. Gao F, Harikumar KG, Dong M, Lam PC, Sexton PM, Christopoulos A, Bordner A, Abagyan R, Miller LJ. Mol Pharmacol; 2009 Aug 28; 76(2):264-74. PubMed ID: 19429716 [Abstract] [Full Text] [Related]
17. Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor. Harikumar KG, Simms J, Christopoulos G, Sexton PM, Miller LJ. Biochemistry; 2009 Dec 15; 48(49):11773-85. PubMed ID: 19886671 [Abstract] [Full Text] [Related]
19. Demonstration of a direct interaction between residue 22 in the carboxyl-terminal half of secretin and the amino-terminal tail of the secretin receptor using photoaffinity labeling. Dong M, Wang Y, Pinon DI, Hadac EM, Miller LJ. J Biol Chem; 1999 Jan 08; 274(2):903-9. PubMed ID: 9873030 [Abstract] [Full Text] [Related]
20. Molecular approximations between residues 21 and 23 of secretin and its receptor: development of a model for peptide docking with the amino terminus of the secretin receptor. Dong M, Lam PC, Gao F, Hosohata K, Pinon DI, Sexton PM, Abagyan R, Miller LJ. Mol Pharmacol; 2007 Aug 08; 72(2):280-90. PubMed ID: 17475809 [Abstract] [Full Text] [Related] Page: [Next] [New Search]