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Journal Abstract Search

218 related items for PubMed ID: 21391610

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  • 8. Hit-to-lead studies on benzimidazole inhibitors of ITK: discovery of a novel class of kinase inhibitors.
    Snow RJ, Abeywardane A, Campbell S, Lord J, Kashem MA, Khine HH, King J, Kowalski JA, Pullen SS, Roma T, Roth GP, Sarko CR, Wilson NS, Winters MP, Wolak JP, Cywin CL.
    Bioorg Med Chem Lett; 2007 Jul 01; 17(13):3660-5. PubMed ID: 17499505
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  • 11. Structure-based design and synthesis of potent benzothiazole inhibitors of interleukin-2 inducible T cell kinase (ITK).
    MacKinnon CH, Lau K, Burch JD, Chen Y, Dines J, Ding X, Eigenbrot C, Heifetz A, Jaochico A, Johnson A, Kraemer J, Kruger S, Krülle TM, Liimatta M, Ly J, Maghames R, Montalbetti CA, Ortwine DF, Pérez-Fuertes Y, Shia S, Stein DB, Trani G, Vaidya DG, Wang X, Bromidge SM, Wu LC, Pei Z.
    Bioorg Med Chem Lett; 2013 Dec 01; 23(23):6331-5. PubMed ID: 24138940
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  • 13. Design, synthesis and structure-activity relationship of indolylindazoles as potent and selective covalent inhibitors of interleukin-2 inducible T-cell kinase (ITK).
    Wang X, Xue G, Pan Z.
    Eur J Med Chem; 2020 Feb 01; 187():111918. PubMed ID: 31830635
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  • 14. Discovery of 7H-pyrrolo[2,3-d]pyrimidine derivatives as selective covalent irreversible inhibitors of interleukin-2-inducible T-cell kinase (Itk).
    Tang G, Liu L, Wang X, Pan Z.
    Eur J Med Chem; 2019 Jul 01; 173():167-183. PubMed ID: 30999237
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  • 17. Discovery, SAR and X-ray structure of 1H-benzimidazole-5-carboxylic acid cyclohexyl-methyl-amides as inhibitors of inducible T-cell kinase (Itk).
    Moriarty KJ, Takahashi H, Pullen SS, Khine HH, Sallati RH, Raymond EL, Woska JR, Jeanfavre DD, Roth GP, Winters MP, Qiao L, Ryan D, DesJarlais R, Robinson D, Wilson M, Bobko M, Cook BN, Lo HY, Nemoto PA, Kashem MA, Wolak JP, White A, Magolda RL, Tomczuk B.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5545-9. PubMed ID: 18819799
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  • 18. 5-Aminomethyl-1H-benzimidazoles as orally active inhibitors of inducible T-cell kinase (Itk).
    Winters MP, Robinson DJ, Khine HH, Pullen SS, Woska JR, Raymond EL, Sellati R, Cywin CL, Snow RJ, Kashem MA, Wolak JP, King J, Kaplita PV, Liu LH, Farrell TM, DesJarlais R, Roth GP, Takahashi H, Moriarty KJ.
    Bioorg Med Chem Lett; 2008 Oct 15; 18(20):5541-4. PubMed ID: 18823779
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  • 19. 6-amino-4-(pyrimidin-4-yl)pyridones: novel glycogen synthase kinase-3β inhibitors.
    Coffman K, Brodney M, Cook J, Lanyon L, Pandit J, Sakya S, Schachter J, Tseng-Lovering E, Wessel M.
    Bioorg Med Chem Lett; 2011 Mar 01; 21(5):1429-33. PubMed ID: 21295469
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  • 20. Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase.
    Li R, Xue L, Zhu T, Jiang Q, Cui X, Yan Z, McGee D, Wang J, Gantla VR, Pickens JC, McGrath D, Chucholowski A, Morris SW, Webb TR.
    J Med Chem; 2006 Feb 09; 49(3):1006-15. PubMed ID: 16451066
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