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Journal Abstract Search

224 related items for PubMed ID: 21392988

  • 21. A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors.
    Shen HC, Ding FX, Deng Q, Xu S, Tong X, Zhang X, Chen Y, Zhou G, Pai LY, Alonso-Galicia M, Roy S, Zhang B, Tata JR, Berger JP, Colletti SL.
    Bioorg Med Chem Lett; 2009 Oct 01; 19(19):5716-21. PubMed ID: 19700315
    [Abstract] [Full Text] [Related]

  • 22. Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH).
    Johnson DS, Ahn K, Kesten S, Lazerwith SE, Song Y, Morris M, Fay L, Gregory T, Stiff C, Dunbar JB, Liimatta M, Beidler D, Smith S, Nomanbhoy TK, Cravatt BF.
    Bioorg Med Chem Lett; 2009 May 15; 19(10):2865-9. PubMed ID: 19386497
    [Abstract] [Full Text] [Related]

  • 23. Design, synthesis and evaluation of polar head group containing 2-keto-oxazole inhibitors of FAAH.
    Rusch M, Zahov S, Vetter IR, Lehr M, Hedberg C.
    Bioorg Med Chem; 2012 Jan 15; 20(2):1100-12. PubMed ID: 22196515
    [Abstract] [Full Text] [Related]

  • 24. Macamides and their synthetic analogs: evaluation of in vitro FAAH inhibition.
    Wu H, Kelley CJ, Pino-Figueroa A, Vu HD, Maher TJ.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5188-97. PubMed ID: 23891163
    [Abstract] [Full Text] [Related]

  • 25. (4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).
    Holtfrerich A, Hanekamp W, Lehr M.
    Eur J Med Chem; 2013 May 01; 63():64-75. PubMed ID: 23455058
    [Abstract] [Full Text] [Related]

  • 26. Binding mode of new (thio)hydantoin inhibitors of fatty acid amide hydrolase: comparison with two original compounds, OL-92 and JP104.
    Michaux C, Muccioli GG, Lambert DM, Wouters J.
    Bioorg Med Chem Lett; 2006 Sep 15; 16(18):4772-6. PubMed ID: 16844375
    [Abstract] [Full Text] [Related]

  • 27. Discovery of boronic acids as novel and potent inhibitors of fatty acid amide hydrolase.
    Minkkilä A, Saario SM, Käsnänen H, Leppänen J, Poso A, Nevalainen T.
    J Med Chem; 2008 Nov 27; 51(22):7057-60. PubMed ID: 18983140
    [Abstract] [Full Text] [Related]

  • 28. Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase.
    Kodani SD, Bhakta S, Hwang SH, Pakhomova S, Newcomer ME, Morisseau C, Hammock BD.
    Bioorg Med Chem Lett; 2018 Feb 15; 28(4):762-768. PubMed ID: 29366648
    [Abstract] [Full Text] [Related]

  • 29. Design of on-target FAAH inhibitors.
    Deutsch DG.
    Chem Biol; 2005 Nov 15; 12(11):1157-8. PubMed ID: 16298293
    [Abstract] [Full Text] [Related]

  • 30. An unprecedented reversible mode of action of β-lactams for the inhibition of human fatty acid amide hydrolase (hFAAH).
    Feledziak M, Michaux C, Lambert DM, Marchand-Brynaert J.
    Eur J Med Chem; 2013 Feb 15; 60():101-11. PubMed ID: 23287055
    [Abstract] [Full Text] [Related]

  • 31. Pyrrolidine-pyrazole ureas as potent and selective inhibitors of 11β-hydroxysteroid-dehydrogenase type 1.
    Venier O, Pascal C, Braun A, Namane C, Mougenot P, Crespin O, Pacquet F, Mougenot C, Monseau C, Onofri B, Dadji-Faïhun R, Leger C, Ben-Hassine M, Van-Pham T, Ragot JL, Philippo C, Güssregen S, Engel C, Farjot G, Noah L, Maniani K, Nicolaï E.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2244-51. PubMed ID: 21439819
    [Abstract] [Full Text] [Related]

  • 32. Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors.
    Seierstad M, Breitenbucher JG.
    J Med Chem; 2008 Dec 11; 51(23):7327-43. PubMed ID: 18983142
    [No Abstract] [Full Text] [Related]

  • 33. Mechanism of inhibition of fatty acid amide hydrolase by sulfonamide-containing benzothiazoles: long residence time derived from increased kinetic barrier and not exclusively from thermodynamic potency.
    Tian G, Paschetto KA, Gharahdaghi F, Gordon E, Wilkins DE, Luo X, Scott CW.
    Biochemistry; 2011 Aug 16; 50(32):6867-78. PubMed ID: 21728345
    [Abstract] [Full Text] [Related]

  • 34. Heteroarylureas with fused bicyclic diamine cores as inhibitors of fatty acid amide hydrolase.
    Keith JM, Jones W, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz M, Scott BP, Wilson SJ, Luo L, Wennerholm M, Chang L, Rizzolio M, Rynberg R, Chaplan S, Guy Breitenbucher J.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127463. PubMed ID: 32784090
    [Abstract] [Full Text] [Related]

  • 35. Identification of productive inhibitor binding orientation in fatty acid amide hydrolase (FAAH) by QM/MM mechanistic modelling.
    Lodola A, Mor M, Rivara S, Christov C, Tarzia G, Piomelli D, Mulholland AJ.
    Chem Commun (Camb); 2008 Jan 14; (2):214-6. PubMed ID: 18092091
    [Abstract] [Full Text] [Related]

  • 36. Discovery and molecular basis of potent noncovalent inhibitors of fatty acid amide hydrolase (FAAH).
    Min X, Thibault ST, Porter AC, Gustin DJ, Carlson TJ, Xu H, Lindstrom M, Xu G, Uyeda C, Ma Z, Li Y, Kayser F, Walker NP, Wang Z.
    Proc Natl Acad Sci U S A; 2011 May 03; 108(18):7379-84. PubMed ID: 21502526
    [Abstract] [Full Text] [Related]

  • 37. Optimization of piperidyl-ureas as inhibitors of soluble epoxide hydrolase.
    Eldrup AB, Soleymanzadeh F, Farrow NA, Kukulka A, De Lombaert S.
    Bioorg Med Chem Lett; 2010 Jan 15; 20(2):571-5. PubMed ID: 19969453
    [Abstract] [Full Text] [Related]

  • 38. Substituted 2-thioxoimidazolidin-4-ones and imidazolidine-2,4-diones as fatty acid amide hydrolase inhibitors templates.
    Muccioli GG, Fazio N, Scriba GK, Poppitz W, Cannata F, Poupaert JH, Wouters J, Lambert DM.
    J Med Chem; 2006 Jan 12; 49(1):417-25. PubMed ID: 16392827
    [Abstract] [Full Text] [Related]

  • 39. Oxime carbamate--discovery of a series of novel FAAH inhibitors.
    Sit SY, Conway CM, Xie K, Bertekap R, Bourin C, Burris KD.
    Bioorg Med Chem Lett; 2010 Feb 01; 20(3):1272-7. PubMed ID: 20036536
    [Abstract] [Full Text] [Related]

  • 40. 1-Aryl-2-((6-aryl)pyrimidin-4-yl)amino)ethanols as competitive inhibitors of fatty acid amide hydrolase.
    Keith JM, Hawryluk N, Apodaca RL, Chambers A, Pierce JM, Seierstad M, Palmer JA, Webb M, Karbarz MJ, Scott BP, Wilson SJ, Luo L, Wennerholm ML, Chang L, Rizzolio M, Chaplan SR, Breitenbucher JG.
    Bioorg Med Chem Lett; 2014 Mar 01; 24(5):1280-4. PubMed ID: 24513048
    [Abstract] [Full Text] [Related]

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