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Journal Abstract Search

133 related items for PubMed ID: 21398123

  • 21. Novel and orally bioavailable inducible nitric oxide synthase inhibitors: synthesis and evaluation of optically active 4,5-dialkyl-2-iminoselenazolidine derivatives.
    Ueda S, Terauchi H, Suzuki K, Yano A, Matsumoto M, Kubo T, Minato H, Arai Y, Tsuji J, Watanabe N.
    Bioorg Med Chem Lett; 2005 Mar 01; 15(5):1361-6. PubMed ID: 15713387
    [Abstract] [Full Text] [Related]

  • 22. 1,2-Dihydro-4-quinazolinamines: potent, highly selective inhibitors of inducible nitric oxide synthase which show antiinflammatory activity in vivo.
    Tinker AC, Beaton HG, Boughton-Smith N, Cook TR, Cooper SL, Fraser-Rae L, Hallam K, Hamley P, McInally T, Nicholls DJ, Pimm AD, Wallace AV.
    J Med Chem; 2003 Mar 13; 46(6):913-6. PubMed ID: 12620067
    [Abstract] [Full Text] [Related]

  • 23. Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor.
    Rao CV, Indranie C, Simi B, Manning PT, Connor JR, Reddy BS.
    Cancer Res; 2002 Jan 01; 62(1):165-70. PubMed ID: 11782374
    [Abstract] [Full Text] [Related]

  • 24. 4,5-dialkylsubstituted 2-imino-1,3-thiazolidine derivatives as potent inducible nitric oxide synthase inhibitors.
    Ueda S, Terauchi H, Yano A, Matsumoto M, Kubo T, Kyoya Y, Suzuki K, Ido M, Kawasaki M.
    Bioorg Med Chem; 2004 Aug 01; 12(15):4101-16. PubMed ID: 15246088
    [Abstract] [Full Text] [Related]

  • 25. Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors.
    Hanan EJ, Fucini RV, Romanowski MJ, Elling RA, Lew W, Purkey HE, VanderPorten EC, Yang W.
    Bioorg Med Chem Lett; 2008 Oct 01; 18(19):5186-9. PubMed ID: 18790636
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  • 26. A novel iNOS and COX-2 inhibitor from the aerial parts of Rodgersia podophylla.
    Chin YW, Park EY, Seo SY, Yoon KD, Ahn MJ, Suh YG, Kim SG, Kim J.
    Bioorg Med Chem Lett; 2006 Sep 01; 16(17):4600-2. PubMed ID: 16784852
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  • 27. 1,3,4-Thiadiazole derivatives as selective inhibitors of iNOS versus nNOS: Synthesis and structure-activity dependence.
    López-Cara LC, Carrión MD, Entrena A, Gallo MA, Espinosa A, López A, Escames G, Acuña-Castroviejo D, Camacho ME.
    Eur J Med Chem; 2012 Apr 01; 50():129-39. PubMed ID: 22336385
    [Abstract] [Full Text] [Related]

  • 28. A strategy of employing aminoheterocycles as amide mimics to identify novel, potent and bioavailable soluble epoxide hydrolase inhibitors.
    Shen HC, Ding FX, Deng Q, Xu S, Tong X, Zhang X, Chen Y, Zhou G, Pai LY, Alonso-Galicia M, Roy S, Zhang B, Tata JR, Berger JP, Colletti SL.
    Bioorg Med Chem Lett; 2009 Oct 01; 19(19):5716-21. PubMed ID: 19700315
    [Abstract] [Full Text] [Related]

  • 29. Design, synthesis, and evaluation of new type of L-amino acids containing pyridine moiety as nitric oxide synthase inhibitor.
    Ijuin R, Umezawa N, Higuchi T.
    Bioorg Med Chem; 2006 May 15; 14(10):3563-70. PubMed ID: 16466923
    [Abstract] [Full Text] [Related]

  • 30. Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.
    Bluhm U, Boucher JL, Buss U, Clement B, Friedrich F, Girreser U, Heber D, Lam T, Lepoivre M, Rostaie-Gerylow M, Wolschendorf U.
    Eur J Med Chem; 2009 Jul 15; 44(7):2877-87. PubMed ID: 19144449
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  • 31. The discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors.
    Buckmelter AJ, Ren L, Laird ER, Rast B, Miknis G, Wenglowsky S, Schlachter S, Welch M, Tarlton E, Grina J, Lyssikatos J, Brandhuber BJ, Morales T, Randolph N, Vigers G, Martinson M, Callejo M.
    Bioorg Med Chem Lett; 2011 Feb 15; 21(4):1248-52. PubMed ID: 21211972
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  • 32. Intracerebroventricular injection of neuronal and inducible nitric oxide synthase inhibitors attenuates fever due to LPS in rats.
    Soszynski D, Chelminiak M.
    J Physiol Pharmacol; 2007 Sep 15; 58(3):551-61. PubMed ID: 17928650
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  • 33. Extensive ligand-based modeling and in silico screening reveal nanomolar inducible nitric oxide synthase (iNOS) inhibitors.
    Suaifan GA, Shehadehh M, Al-Ijel H, Taha MO.
    J Mol Graph Model; 2012 Jul 15; 37():1-26. PubMed ID: 22609742
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  • 34. Design, synthesis, and activity of 2-imidazol-1-ylpyrimidine derived inducible nitric oxide synthase dimerization inhibitors.
    Davey DD, Adler M, Arnaiz D, Eagen K, Erickson S, Guilford W, Kenrick M, Morrissey MM, Ohlmeyer M, Pan G, Paradkar VM, Parkinson J, Polokoff M, Saionz K, Santos C, Subramanyam B, Vergona R, Wei RG, Whitlow M, Ye B, Zhao ZS, Devlin JJ, Phillips G.
    J Med Chem; 2007 Mar 22; 50(6):1146-57. PubMed ID: 17315988
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  • 35. Synthesis and biological evaluation of indazole derivatives.
    Claramunt RM, López C, López A, Pérez-Medina C, Pérez-Torralba M, Alkorta I, Elguero J, Escames G, Acuña-Castroviejo D.
    Eur J Med Chem; 2011 Apr 22; 46(4):1439-47. PubMed ID: 21334118
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  • 36. The discovery of fluoropyridine-based inhibitors of the factor VIIa/TF complex--Part 2.
    Kohrt JT, Filipski KJ, Cody WL, Cai C, Dudley DA, Van Huis CA, Willardsen JA, Narasimhan LS, Zhang E, Rapundalo ST, Saiya-Cork K, Leadley RJ, Edmunds JJ.
    Bioorg Med Chem Lett; 2006 Feb 15; 16(4):1060-4. PubMed ID: 16289811
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  • 37. Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors.
    Sun D, Wang Z, Caille S, DeGraffenreid M, Gonzalez-Lopez de Turiso F, Hungate R, Jaen JC, Jiang B, Julian LD, Kelly R, McMinn DL, Kaizerman J, Rew Y, Sudom A, Tu H, Ursu S, Walker N, Willcockson M, Yan X, Ye Q, Powers JP.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):405-10. PubMed ID: 21093258
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  • 38. Development of urea and thiourea kynurenamine derivatives: synthesis, molecular modeling, and biological evaluation as nitric oxide synthase inhibitors.
    Chayah M, Carrión MD, Gallo MA, Jiménez R, Duarte J, Camacho ME.
    ChemMedChem; 2015 May 01; 10(5):874-82. PubMed ID: 25801086
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  • 39. Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): synthesis and biological evaluation.
    Claramunt RM, López C, Pérez-Medina C, Pérez-Torralba M, Elguero J, Escames G, Acuña-Castroviejo D.
    Bioorg Med Chem; 2009 Sep 01; 17(17):6180-7. PubMed ID: 19679481
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  • 40. 2-Amino-9-aryl-3-cyano-4-methyl-7-oxo-6,7,8,9-tetrahydropyrido[2',3':4,5]thieno[2,3-b]pyridine derivatives as selective progesterone receptor agonists.
    Wang Y, Duraiswami C, Madauss KP, Tran TB, Williams SP, Deng SJ, Graybill TL, Hammond M, Jones DG, Grygielko ET, Bray JD, Thompson SK.
    Bioorg Med Chem Lett; 2009 Sep 01; 19(17):4916-9. PubMed ID: 19664922
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