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213 related items for PubMed ID: 21399657

  • 1. Mutation of thyroid hormone receptor-β in mice predisposes to the development of mammary tumors.
    Guigon CJ, Kim DW, Willingham MC, Cheng SY.
    Oncogene; 2011 Jul 28; 30(30):3381-90. PubMed ID: 21399657
    [Abstract] [Full Text] [Related]

  • 2. Role of TSH in the spontaneous development of asymmetrical thyroid carcinoma in mice with a targeted mutation in a single allele of the thyroid hormone-β receptor.
    Zhao L, Zhu X, Won Park J, Fozzatti L, Willingham M, Cheng SY.
    Endocrinology; 2012 Oct 28; 153(10):5090-100. PubMed ID: 22919057
    [Abstract] [Full Text] [Related]

  • 3. Regulation of beta-catenin by a novel nongenomic action of thyroid hormone beta receptor.
    Guigon CJ, Zhao L, Lu C, Willingham MC, Cheng SY.
    Mol Cell Biol; 2008 Jul 28; 28(14):4598-608. PubMed ID: 18474620
    [Abstract] [Full Text] [Related]

  • 4. Stat5 regulates the phosphatidylinositol 3-kinase/Akt1 pathway during mammary gland development and tumorigenesis.
    Schmidt JW, Wehde BL, Sakamoto K, Triplett AA, Anderson SM, Tsichlis PN, Leone G, Wagner KU.
    Mol Cell Biol; 2014 Apr 28; 34(7):1363-77. PubMed ID: 24469394
    [Abstract] [Full Text] [Related]

  • 5. Synergistic signaling of KRAS and thyroid hormone receptor β mutants promotes undifferentiated thyroid cancer through MYC up-regulation.
    Zhu X, Zhao L, Park JW, Willingham MC, Cheng SY.
    Neoplasia; 2014 Sep 28; 16(9):757-69. PubMed ID: 25246276
    [Abstract] [Full Text] [Related]

  • 6. Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.
    Kim WG, Park JW, Willingham MC, Cheng SY.
    Endocrinology; 2013 Aug 28; 154(8):2936-47. PubMed ID: 23748362
    [Abstract] [Full Text] [Related]

  • 7. PTEN deficiency accelerates tumour progression in a mouse model of thyroid cancer.
    Guigon CJ, Zhao L, Willingham MC, Cheng SY.
    Oncogene; 2009 Jan 29; 28(4):509-17. PubMed ID: 18997818
    [Abstract] [Full Text] [Related]

  • 8. A tumor suppressor role for thyroid hormone beta receptor in a mouse model of thyroid carcinogenesis.
    Kato Y, Ying H, Willingham MC, Cheng SY.
    Endocrinology; 2004 Oct 29; 145(10):4430-8. PubMed ID: 15231697
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of STAT3 signaling blocks obesity-induced mammary hyperplasia in a mouse model.
    Park JW, Zhao L, Willingham MC, Cheng SY.
    Am J Cancer Res; 2017 Oct 29; 7(3):727-739. PubMed ID: 28401024
    [Abstract] [Full Text] [Related]

  • 10. Overexpression of the tumor suppressor gene phosphatase and tensin homologue partially inhibits wnt-1-induced mammary tumorigenesis.
    Zhao H, Cui Y, Dupont J, Sun H, Hennighausen L, Yakar S.
    Cancer Res; 2005 Aug 01; 65(15):6864-73. PubMed ID: 16061670
    [Abstract] [Full Text] [Related]

  • 11. Multi-tissue gene-expression analysis in a mouse model of thyroid hormone resistance.
    Miller LD, McPhie P, Suzuki H, Kato Y, Liu ET, Cheng SY.
    Genome Biol; 2004 Aug 01; 5(5):R31. PubMed ID: 15128445
    [Abstract] [Full Text] [Related]

  • 12. Activation of tumor cell proliferation by thyroid hormone in a mouse model of follicular thyroid carcinoma.
    Lu C, Zhu X, Willingham MC, Cheng SY.
    Oncogene; 2012 Apr 19; 31(16):2007-16. PubMed ID: 21909131
    [Abstract] [Full Text] [Related]

  • 13. Marked potentiation of the dominant negative action of a mutant thyroid hormone receptor beta in mice by the ablation of one wild-type beta allele.
    Suzuki H, Zhang XY, Forrest D, Willingham MC, Cheng SY.
    Mol Endocrinol; 2003 May 19; 17(5):895-907. PubMed ID: 12576488
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of STAT3 activity delays obesity-induced thyroid carcinogenesis in a mouse model.
    Park JW, Han CR, Zhao L, Willingham MC, Cheng SY.
    Endocr Relat Cancer; 2016 Jan 19; 23(1):53-63. PubMed ID: 26552408
    [Abstract] [Full Text] [Related]

  • 15. Novel oncogenic actions of TRbeta mutants in tumorigenesis.
    Guigon CJ, Cheng SY.
    IUBMB Life; 2009 May 19; 61(5):528-36. PubMed ID: 19391168
    [Abstract] [Full Text] [Related]

  • 16. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis.
    Mancini ML, Lien EC, Toker A.
    Oncotarget; 2016 Apr 05; 7(14):17301-13. PubMed ID: 27004402
    [Abstract] [Full Text] [Related]

  • 17. SAHA-induced loss of tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model.
    Zhu X, Kim DW, Zhao L, Willingham MC, Cheng SY.
    Endocr Relat Cancer; 2016 Jul 05; 23(7):521-33. PubMed ID: 27267120
    [Abstract] [Full Text] [Related]

  • 18. An unliganded thyroid hormone beta receptor activates the cyclin D1/cyclin-dependent kinase/retinoblastoma/E2F pathway and induces pituitary tumorigenesis.
    Furumoto H, Ying H, Chandramouli GV, Zhao L, Walker RL, Meltzer PS, Willingham MC, Cheng SY.
    Mol Cell Biol; 2005 Jan 05; 25(1):124-35. PubMed ID: 15601836
    [Abstract] [Full Text] [Related]

  • 19. Loss of tyrosine phosphorylation at Y406 abrogates the tumor suppressor functions of the thyroid hormone receptor β.
    Park JW, Zhao L, Willingham MC, Cheng SY.
    Mol Carcinog; 2017 Feb 05; 56(2):489-498. PubMed ID: 27254276
    [Abstract] [Full Text] [Related]

  • 20. Reactivation of the silenced thyroid hormone receptor β gene expression delays thyroid tumor progression.
    Kim WG, Zhu X, Kim DW, Zhang L, Kebebew E, Cheng SY.
    Endocrinology; 2013 Jan 05; 154(1):25-35. PubMed ID: 23183175
    [Abstract] [Full Text] [Related]

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