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Journal Abstract Search

172 related items for PubMed ID: 21420857

  • 1. Decahydroquinoline amides as highly selective CB2 agonists: role of selectivity on in vivo efficacy in a rodent model of analgesia.
    Manley PJ, Zartman A, Paone DV, Burgey CS, Henze DA, Della Penna K, Desai R, Leitl MD, Lemaire W, White RB, Yeh S, Urban MO, Kane SA, Hartman GD, Bilodeau MT, Trotter BW.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2359-64. PubMed ID: 21420857
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  • 2. Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy.
    Trotter BW, Nanda KK, Burgey CS, Potteiger CM, Deng JZ, Green AI, Hartnett JC, Kett NR, Wu Z, Henze DA, Della Penna K, Desai R, Leitl MD, Lemaire W, White RB, Yeh S, Urban MO, Kane SA, Hartman GD, Bilodeau MT.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2354-8. PubMed ID: 21420860
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  • 3. Pyridine-3-carboxamides as novel CB(2) agonists for analgesia.
    Mitchell WL, Giblin GM, Naylor A, Eatherton AJ, Slingsby BP, Rawlings AD, Jandu KS, Haslam CP, Brown AJ, Goldsmith P, Clayton NM, Wilson AW, Chessell IP, Green RH, Whittington AR, Wall ID.
    Bioorg Med Chem Lett; 2009 Jan 01; 19(1):259-63. PubMed ID: 19010671
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  • 4. Optimisation of a novel series of selective CNS penetrant CB(2) agonists.
    Watson C, Owen DR, Harding D, Kon-I K, Lewis ML, Mason HJ, Matsumizu M, Mukaiyama T, Rodriguez-Lens M, Shima A, Takeuchi M, Tran I, Young T.
    Bioorg Med Chem Lett; 2011 Jul 15; 21(14):4284-7. PubMed ID: 21669533
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  • 6. Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists.
    Chu GH, Saeui CT, Worm K, Weaver DG, Goodman AJ, Broadrup RL, Cassel JA, DeHaven RN, LaBuda CJ, Koblish M, Brogdon B, Smith S, Le Bourdonnec B, Dolle RE.
    Bioorg Med Chem Lett; 2009 Oct 15; 19(20):5931-5. PubMed ID: 19736007
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  • 7. Structure-activity relationships of 2,4-diphenyl-1H-imidazole analogs as CB2 receptor agonists for the treatment of chronic pain.
    Yang SW, Smotryski J, Matasi J, Ho G, Tulshian D, Greenlee WJ, Brusa R, Beltramo M, Cox K.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):182-5. PubMed ID: 21115245
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  • 8. Discovery and optimization of novel purines as potent and selective CB2 agonists.
    Hollinshead SP, Astles PC, Chambers MG, Johnson MP, Palmer J, Tidwell MW.
    Bioorg Med Chem Lett; 2012 Aug 01; 22(15):4962-6. PubMed ID: 22765893
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  • 18. New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists.
    Manera C, Cascio MG, Benetti V, Allarà M, Tuccinardi T, Martinelli A, Saccomanni G, Vivoli E, Ghelardini C, Di Marzo V, Ferrarini PL.
    Bioorg Med Chem Lett; 2007 Dec 01; 17(23):6505-10. PubMed ID: 17942307
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  • 19. Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone: a potent, orally bioavailable human CB1/CB2 dual agonist with antihyperalgesic properties and restricted central nervous system penetration.
    Dziadulewicz EK, Bevan SJ, Brain CT, Coote PR, Culshaw AJ, Davis AJ, Edwards LJ, Fisher AJ, Fox AJ, Gentry C, Groarke A, Hart TW, Huber W, James IF, Kesingland A, La Vecchia L, Loong Y, Lyothier I, McNair K, O'Farrell C, Peacock M, Portmann R, Schopfer U, Yaqoob M, Zadrobilek J.
    J Med Chem; 2007 Aug 09; 50(16):3851-6. PubMed ID: 17630726
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  • 20. Latest advances in cannabinoid receptor agonists.
    Thakur GA, Tichkule R, Bajaj S, Makriyannis A.
    Expert Opin Ther Pat; 2009 Dec 09; 19(12):1647-73. PubMed ID: 19939187
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