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116 related items for PubMed ID: 21420961

  • 1. Crystal structure of E339K mutated human glucokinase reveals changes in the ATP binding site.
    Liu Q, Shen Y, Liu S, Weng J, Liu J.
    FEBS Lett; 2011 Apr 20; 585(8):1175-9. PubMed ID: 21420961
    [Abstract] [Full Text] [Related]

  • 2. Identification and characterization of the ATP-binding site in human pancreatic glucokinase.
    Marotta DE, Anand GR, Anderson TA, Miller SP, Okar DA, Levitt DG, Lange AJ.
    Arch Biochem Biophys; 2005 Apr 01; 436(1):23-31. PubMed ID: 15752705
    [Abstract] [Full Text] [Related]

  • 3. The crystal structure of Trypanosoma cruzi glucokinase reveals features determining oligomerization and anomer specificity of hexose-phosphorylating enzymes.
    Cordeiro AT, Cáceres AJ, Vertommen D, Concepción JL, Michels PA, Versées W.
    J Mol Biol; 2007 Oct 05; 372(5):1215-26. PubMed ID: 17761195
    [Abstract] [Full Text] [Related]

  • 4. The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.
    Lánský Z, Kubala M, Ettrich R, Kutý M, Plásek J, Teisinger J, Schoner W, Amler E.
    Biochemistry; 2004 Jul 06; 43(26):8303-11. PubMed ID: 15222743
    [Abstract] [Full Text] [Related]

  • 5. Catalytic activation of human glucokinase by substrate binding: residue contacts involved in the binding of D-glucose to the super-open form and conformational transitions.
    Molnes J, Bjørkhaug L, Søvik O, Njølstad PR, Flatmark T.
    FEBS J; 2008 May 06; 275(10):2467-81. PubMed ID: 18397317
    [Abstract] [Full Text] [Related]

  • 6. The hydroxyl of threonine 13 of the bovine 70-kDa heat shock cognate protein is essential for transducing the ATP-induced conformational change.
    Sousa MC, McKay DB.
    Biochemistry; 1998 Nov 03; 37(44):15392-9. PubMed ID: 9799500
    [Abstract] [Full Text] [Related]

  • 7. Mutation of serine-46 to aspartate in the histidine-containing protein of Escherichia coli mimics the inactivation by phosphorylation of serine-46 in HPrs from gram-positive bacteria.
    Napper S, Anderson JW, Georges F, Quail JW, Delbaere LT, Waygood EB.
    Biochemistry; 1996 Sep 03; 35(35):11260-7. PubMed ID: 8784179
    [Abstract] [Full Text] [Related]

  • 8. Binding kinetics of glucose and allosteric activators to human glucokinase reveal multiple conformational states.
    Antoine M, Boutin JA, Ferry G.
    Biochemistry; 2009 Jun 16; 48(23):5466-82. PubMed ID: 19459610
    [Abstract] [Full Text] [Related]

  • 9. From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
    Sagen JV, Odili S, Bjørkhaug L, Zelent D, Buettger C, Kwagh J, Stanley C, Dahl-Jørgensen K, de Beaufort C, Bell GI, Han Y, Grimsby J, Taub R, Molven A, Søvik O, Njølstad PR, Matschinsky FM.
    Diabetes; 2006 Jun 16; 55(6):1713-22. PubMed ID: 16731834
    [Abstract] [Full Text] [Related]

  • 10. Glucose-induced conformational changes in glucokinase mediate allosteric regulation: transient kinetic analysis.
    Heredia VV, Thomson J, Nettleton D, Sun S.
    Biochemistry; 2006 Jun 20; 45(24):7553-62. PubMed ID: 16768451
    [Abstract] [Full Text] [Related]

  • 11. Sugar binding to recombinant wild-type and mutant glucokinase monitored by kinetic measurement and tryptophan fluorescence.
    Zelent B, Odili S, Buettger C, Shiota C, Grimsby J, Taub R, Magnuson MA, Vanderkooi JM, Matschinsky FM.
    Biochem J; 2008 Jul 15; 413(2):269-80. PubMed ID: 18370929
    [Abstract] [Full Text] [Related]

  • 12. Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase.
    Kamata K, Mitsuya M, Nishimura T, Eiki J, Nagata Y.
    Structure; 2004 Mar 15; 12(3):429-38. PubMed ID: 15016359
    [Abstract] [Full Text] [Related]

  • 13. Glucokinase and glucose homeostasis: proven concepts and new ideas.
    Zelent D, Najafi H, Odili S, Buettger C, Weik-Collins H, Li C, Doliba N, Grimsby J, Matschinsky FM.
    Biochem Soc Trans; 2005 Feb 15; 33(Pt 1):306-10. PubMed ID: 15667334
    [Abstract] [Full Text] [Related]

  • 14. Identification and analysis of novel R308K mutation in glucokinase of type 2 diabetic patient and its kinetic correlation.
    Yellapu NK, Valasani KR, Pasupuleti SK, Gopal S, Potukuchi Venkata Gurunadha Krishna S, Matcha B.
    Biotechnol Appl Biochem; 2014 Feb 15; 61(5):572-81. PubMed ID: 24447076
    [Abstract] [Full Text] [Related]

  • 15. ATP-binding site of human brain hexokinase as studied by molecular modeling and site-directed mutagenesis.
    Zeng C, Aleshin AE, Hardie JB, Harrison RW, Fromm HJ.
    Biochemistry; 1996 Oct 08; 35(40):13157-64. PubMed ID: 8855953
    [Abstract] [Full Text] [Related]

  • 16. Crystal structures of the Mnk2 kinase domain reveal an inhibitory conformation and a zinc binding site.
    Jauch R, Jäkel S, Netter C, Schreiter K, Aicher B, Jäckle H, Wahl MC.
    Structure; 2005 Oct 08; 13(10):1559-68. PubMed ID: 16216586
    [Abstract] [Full Text] [Related]

  • 17. Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
    Krajewski WW, Collins R, Holmberg-Schiavone L, Jones TA, Karlberg T, Mowbray SL.
    J Mol Biol; 2008 Jan 04; 375(1):217-28. PubMed ID: 18005987
    [Abstract] [Full Text] [Related]

  • 18. Autophosphorylation of Archaeoglobus fulgidus Rio2 and crystal structures of its nucleotide-metal ion complexes.
    LaRonde-LeBlanc N, Guszczynski T, Copeland T, Wlodawer A.
    FEBS J; 2005 Jun 04; 272(11):2800-10. PubMed ID: 15943813
    [Abstract] [Full Text] [Related]

  • 19. Catalytic independent functions of a protein kinase as revealed by a kinase-dead mutant: study of the Lys72His mutant of cAMP-dependent kinase.
    Iyer GH, Garrod S, Woods VL, Taylor SS.
    J Mol Biol; 2005 Sep 02; 351(5):1110-22. PubMed ID: 16054648
    [Abstract] [Full Text] [Related]

  • 20. Structural model of human glucokinase in complex with glucose and ATP: implications for the mutants that cause hypo- and hyperglycemia.
    Mahalingam B, Cuesta-Munoz A, Davis EA, Matschinsky FM, Harrison RW, Weber IT.
    Diabetes; 1999 Sep 02; 48(9):1698-705. PubMed ID: 10480597
    [Abstract] [Full Text] [Related]

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