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508 related items for PubMed ID: 21425311

  • 1. Delayed-onset caspase-dependent massive hepatocyte apoptosis upon Fas activation in Bak/Bax-deficient mice.
    Hikita H, Takehara T, Kodama T, Shimizu S, Shigekawa M, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Shimizu S, Tsujimoto Y, Hayashi N.
    Hepatology; 2011 Jul; 54(1):240-51. PubMed ID: 21425311
    [Abstract] [Full Text] [Related]

  • 2. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 3. Bax and Bak genes are essential for maximum apoptotic response by curcumin, a polyphenolic compound and cancer chemopreventive agent derived from turmeric, Curcuma longa.
    Shankar S, Srivastava RK.
    Carcinogenesis; 2007 Jun 01; 28(6):1277-86. PubMed ID: 17277231
    [Abstract] [Full Text] [Related]

  • 4. NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis.
    Hatano E, Bennett BL, Manning AM, Qian T, Lemasters JJ, Brenner DA.
    Gastroenterology; 2001 Apr 01; 120(5):1251-62. PubMed ID: 11266388
    [Abstract] [Full Text] [Related]

  • 5. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
    Yin XM, Wang K, Gross A, Zhao Y, Zinkel S, Klocke B, Roth KA, Korsmeyer SJ.
    Nature; 1999 Aug 26; 400(6747):886-91. PubMed ID: 10476969
    [Abstract] [Full Text] [Related]

  • 6. In vivo evidence that caspase-3 is required for Fas-mediated apoptosis of hepatocytes.
    Woo M, Hakem A, Elia AJ, Hakem R, Duncan GS, Patterson BJ, Mak TW.
    J Immunol; 1999 Nov 01; 163(9):4909-16. PubMed ID: 10528193
    [Abstract] [Full Text] [Related]

  • 7. Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.
    Panaretakis T, Pokrovskaja K, Shoshan MC, Grandér D.
    Oncogene; 2003 Jul 17; 22(29):4543-56. PubMed ID: 12881711
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of the ER Ca2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis.
    Janssen K, Horn S, Niemann MT, Daniel PT, Schulze-Osthoff K, Fischer U.
    J Cell Sci; 2009 Dec 15; 122(Pt 24):4481-91. PubMed ID: 19920074
    [Abstract] [Full Text] [Related]

  • 9. Apoptosis induced by Semliki Forest virus is RNA replication dependent and mediated via Bak.
    Urban C, Rhême C, Maerz S, Berg B, Pick R, Nitschke R, Borner C.
    Cell Death Differ; 2008 Sep 15; 15(9):1396-407. PubMed ID: 18437160
    [Abstract] [Full Text] [Related]

  • 10. TAT-apoptosis repressor with caspase recruitment domain protein transduction rescues mice from fulminant liver failure.
    An J, Harms C, Lättig-Tünnemann G, Sellge G, Mandić AD, Malato Y, Heuser A, Endres M, Trautwein C, Donath S.
    Hepatology; 2012 Aug 15; 56(2):715-26. PubMed ID: 22392694
    [Abstract] [Full Text] [Related]

  • 11. Prolonged, but not acute, glutathione depletion promotes Fas-mediated mitochondrial permeability transition and apoptosis in mice.
    Haouzi D, Lekehal M, Tinel M, Vadrot N, Caussanel L, Lettéron P, Moreau A, Feldmann G, Fau D, Pessayre D.
    Hepatology; 2001 May 15; 33(5):1181-8. PubMed ID: 11343247
    [Abstract] [Full Text] [Related]

  • 12. Mechanism of hepatocytes apoptosis induced by the proapoptosis protein Bid.
    Bai L, Cao CP, Mao GP.
    Chin J Dig Dis; 2004 May 15; 5(4):175-80. PubMed ID: 15612888
    [Abstract] [Full Text] [Related]

  • 13. Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.
    Boya P, Gonzalez-Polo RA, Poncet D, Andreau K, Vieira HL, Roumier T, Perfettini JL, Kroemer G.
    Oncogene; 2003 Jun 19; 22(25):3927-36. PubMed ID: 12813466
    [Abstract] [Full Text] [Related]

  • 14. BH3-only protein bid participates in the Bcl-2 network in healthy liver cells.
    Hikita H, Takehara T, Kodama T, Shimizu S, Hosui A, Miyagi T, Tatsumi T, Ishida H, Ohkawa K, Li W, Kanto T, Hiramatsu N, Hennighausen L, Yin XM, Hayashi N.
    Hepatology; 2009 Dec 19; 50(6):1972-80. PubMed ID: 19839062
    [Abstract] [Full Text] [Related]

  • 15. Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation.
    Zheng TS, Hunot S, Kuida K, Momoi T, Srinivasan A, Nicholson DW, Lazebnik Y, Flavell RA.
    Nat Med; 2000 Nov 19; 6(11):1241-7. PubMed ID: 11062535
    [Abstract] [Full Text] [Related]

  • 16. Edaravone prevents Fas-induced fulminant hepatic failure in mice by regulating mitochondrial Bcl-xL and Bax.
    Miyasou T, Kwon AH, Tsuji K, Qiu Z, Okumura T, Kamiyama Y.
    Shock; 2008 Aug 19; 30(2):212-6. PubMed ID: 18180697
    [Abstract] [Full Text] [Related]

  • 17. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.
    Wei MC, Zong WX, Cheng EH, Lindsten T, Panoutsakopoulou V, Ross AJ, Roth KA, MacGregor GR, Thompson CB, Korsmeyer SJ.
    Science; 2001 Apr 27; 292(5517):727-30. PubMed ID: 11326099
    [Abstract] [Full Text] [Related]

  • 18. Fas-induced apoptosis in mouse hepatocytes is dependent on C/EBPbeta.
    Mukherjee D, Kaestner KH, Kovalovich KK, Greenbaum LE.
    Hepatology; 2001 May 27; 33(5):1166-72. PubMed ID: 11343245
    [Abstract] [Full Text] [Related]

  • 19. DRP1-dependent apoptotic mitochondrial fission occurs independently of BAX, BAK and APAF1 to amplify cell death by BID and oxidative stress.
    Oettinghaus B, D'Alonzo D, Barbieri E, Restelli LM, Savoia C, Licci M, Tolnay M, Frank S, Scorrano L.
    Biochim Biophys Acta; 2016 Aug 27; 1857(8):1267-1276. PubMed ID: 26997499
    [Abstract] [Full Text] [Related]

  • 20. Death receptors and mitochondria: life depends on the liver.
    Parsons MJ, Green DR.
    Hepatology; 2011 Jul 27; 54(1):13-5. PubMed ID: 21563197
    [No Abstract] [Full Text] [Related]

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