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133 related items for PubMed ID: 21427169
21. siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model. Gonzalez-Gonzalez E, Ra H, Hickerson RP, Wang Q, Piyawattanametha W, Mandella MJ, Kino GS, Leake D, Avilion AA, Solgaard O, Doyle TC, Contag CH, Kaspar RL. Gene Ther; 2009 Aug; 16(8):963-72. PubMed ID: 19474811 [Abstract] [Full Text] [Related]
22. Caspase-8 and caspase-3 small interfering RNA decreases ischemia/reperfusion injury to the liver in mice. Contreras JL, Vilatoba M, Eckstein C, Bilbao G, Anthony Thompson J, Eckhoff DE. Surgery; 2004 Aug; 136(2):390-400. PubMed ID: 15300206 [Abstract] [Full Text] [Related]
23. In vivo gene silencing in solid tumors by targeted electrically mediated siRNA delivery. Golzio M, Mazzolini L, Ledoux A, Paganin A, Izard M, Hellaudais L, Bieth A, Pillaire MJ, Cazaux C, Hoffmann JS, Couderc B, Teissié J. Gene Ther; 2007 May; 14(9):752-9. PubMed ID: 17344906 [Abstract] [Full Text] [Related]
24. RNA interfering connective tissue growth factor prevents rat hepatic stellate cell activation and extracellular matrix production. Li G, Li D, Xie Q, Shi Y, Jiang S, Jin Y. J Gene Med; 2008 Sep; 10(9):1039-47. PubMed ID: 18613219 [Abstract] [Full Text] [Related]
25. Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook. Shukla S, Sumaria CS, Pradeepkumar PI. ChemMedChem; 2010 Mar 01; 5(3):328-49. PubMed ID: 20043313 [Abstract] [Full Text] [Related]
26. Silencing the cardiac potassium channel Kv4.3 by RNA interference in a CHO expression system. Cotella D, Jost N, Darna M, Radicke S, Ravens U, Wettwer E. Biochem Biophys Res Commun; 2005 May 06; 330(2):555-60. PubMed ID: 15796918 [Abstract] [Full Text] [Related]
27. Optical in vivo imaging of electrically mediated delivery of siRNA into muscle for gene function analysis. Golzio M, Teissié J. Methods Mol Biol; 2008 May 06; 423():279-87. PubMed ID: 18370206 [Abstract] [Full Text] [Related]
29. Competition potency of siRNA is specified by the 5'-half sequence of the guide strand. Yoo JW, Kim S, Lee DK. Biochem Biophys Res Commun; 2008 Feb 29; 367(1):78-83. PubMed ID: 18164261 [Abstract] [Full Text] [Related]
30. Rational design and in vitro and in vivo delivery of Dicer substrate siRNA. Amarzguioui M, Lundberg P, Cantin E, Hagstrom J, Behlke MA, Rossi JJ. Nat Protoc; 2006 Feb 29; 1(2):508-17. PubMed ID: 17406276 [Abstract] [Full Text] [Related]
32. siRNA-mediated silencing of Cockayne Cyndrome group B gene potentiates radiation-induced apoptosis and antiproliferative effect in HeLa cells. Liu F, Yu ZJ, Sui JL, Bai B, Zhou PK. Chin Med J (Engl); 2006 May 05; 119(9):731-9. PubMed ID: 16701013 [Abstract] [Full Text] [Related]
33. Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Minakuchi Y, Takeshita F, Kosaka N, Sasaki H, Yamamoto Y, Kouno M, Honma K, Nagahara S, Hanai K, Sano A, Kato T, Terada M, Ochiya T. Nucleic Acids Res; 2004 Jul 22; 32(13):e109. PubMed ID: 15272050 [Abstract] [Full Text] [Related]
34. RNAi-mediated suppression of constitutive pulmonary gene expression by small interfering RNA in mice. Gutbier B, Kube SM, Reppe K, Santel A, Lange C, Kaufmann J, Suttorp N, Witzenrath M. Pulm Pharmacol Ther; 2010 Aug 22; 23(4):334-44. PubMed ID: 20362688 [Abstract] [Full Text] [Related]
35. Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine-Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans. Ayyar VS, Song D, Zheng S, Carpenter T, Heald DL. J Pharmacol Exp Ther; 2021 Nov 22; 379(2):134-146. PubMed ID: 34413198 [Abstract] [Full Text] [Related]
36. Mechanistic Pharmacokinetics and Pharmacodynamics of GalNAc-siRNA: Translational Model Involving Competitive Receptor-Mediated Disposition and RISC-Dependent Gene Silencing Applied to Givosiran. Ayyar VS, Song D. J Pharm Sci; 2024 Jan 22; 113(1):176-190. PubMed ID: 37871778 [Abstract] [Full Text] [Related]
38. Noninvasive imaging of lipid nanoparticle-mediated systemic delivery of small-interfering RNA to the liver. Tao W, Davide JP, Cai M, Zhang GJ, South VJ, Matter A, Ng B, Zhang Y, Sepp-Lorenzino L. Mol Ther; 2010 Sep 22; 18(9):1657-66. PubMed ID: 20628357 [Abstract] [Full Text] [Related]