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288 related items for PubMed ID: 21435243

  • 1. The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.
    De Santi M, Galluzzi L, Lucarini S, Paoletti MF, Fraternale A, Duranti A, De Marco C, Fanelli M, Zaffaroni N, Brandi G, Magnani M.
    Breast Cancer Res; 2011 Mar 24; 13(2):R33. PubMed ID: 21435243
    [Abstract] [Full Text] [Related]

  • 2. Antitumoral activity of indole-3-carbinol cyclic tri- and tetrameric derivatives mixture in human breast cancer cells: in vitro and in vivo studies.
    Brandi G, Fraternale A, Lucarini S, Paiardini M, De Santi M, Cervasi B, Paoletti MF, Galluzzi L, Duranti A, Magnani M.
    Anticancer Agents Med Chem; 2013 May 24; 13(4):654-62. PubMed ID: 23092288
    [Abstract] [Full Text] [Related]

  • 3. Induction of endoplasmic reticulum stress response by the indole-3-carbinol cyclic tetrameric derivative CTet in human breast cancer cell lines.
    Galluzzi L, De Santi M, Crinelli R, De Marco C, Zaffaroni N, Duranti A, Brandi G, Magnani M.
    PLoS One; 2012 May 24; 7(8):e43249. PubMed ID: 22905241
    [Abstract] [Full Text] [Related]

  • 4. The Indole-3-carbinol cyclic tetrameric derivative CTet synergizes with cisplatin and doxorubicin in triple-negative breast cancer cell lines.
    De Santi M, Galluzzi L, Duranti A, Magnani M, Brandi G.
    Anticancer Res; 2013 May 24; 33(5):1867-72. PubMed ID: 23645732
    [Abstract] [Full Text] [Related]

  • 5. A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell lines.
    Brandi G, Paiardini M, Cervasi B, Fiorucci C, Filippone P, De Marco C, Zaffaroni N, Magnani M.
    Cancer Res; 2003 Jul 15; 63(14):4028-36. PubMed ID: 12874002
    [Abstract] [Full Text] [Related]

  • 6. Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple negative xenograft growth.
    Chai Y, Lee HJ, Shaik AA, Nkhata K, Xing C, Zhang J, Jeong SJ, Kim SH, Lu J.
    Breast Cancer Res; 2010 Jul 15; 12(5):R67. PubMed ID: 20809980
    [Abstract] [Full Text] [Related]

  • 7. Targeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat.
    Tate CR, Rhodes LV, Segar HC, Driver JL, Pounder FN, Burow ME, Collins-Burow BM.
    Breast Cancer Res; 2012 May 21; 14(3):R79. PubMed ID: 22613095
    [Abstract] [Full Text] [Related]

  • 8. Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.
    Caruso JA, Campana R, Wei C, Su CH, Hanks AM, Bornmann WG, Keyomarsi K.
    Cell Cycle; 2014 May 21; 13(16):2587-99. PubMed ID: 25486199
    [Abstract] [Full Text] [Related]

  • 9. 1-Benzyl-indole-3-carbinol is a novel indole-3-carbinol derivative with significantly enhanced potency of anti-proliferative and anti-estrogenic properties in human breast cancer cells.
    Nguyen HH, Lavrenov SN, Sundar SN, Nguyen DH, Tseng M, Marconett CN, Kung J, Staub RE, Preobrazhenskaya MN, Bjeldanes LF, Firestone GL.
    Chem Biol Interact; 2010 Aug 05; 186(3):255-66. PubMed ID: 20570586
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of a gamma-cyclodextrin-based formulation of the anticancer agent 5,6,11,12,17,18,23,24-octahydrocyclododeca[1,2-b:4,5-b':7,8-b'':10,11-b''']tetraindole (CTet).
    Lucarini S, De Santi M, Antonietti F, Brandi G, Diamantini G, Fraternale A, Paoletti MF, Tontini A, Magnani M, Duranti A.
    Molecules; 2010 Jun 04; 15(6):4085-93. PubMed ID: 20657428
    [Abstract] [Full Text] [Related]

  • 11. Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells.
    Tin AS, Park AH, Sundar SN, Firestone GL.
    BMC Biol; 2014 Sep 12; 12():72. PubMed ID: 25209720
    [Abstract] [Full Text] [Related]

  • 12. Indole-3-carbinol inhibits the expression of cyclin-dependent kinase-6 and induces a G1 cell cycle arrest of human breast cancer cells independent of estrogen receptor signaling.
    Cover CM, Hsieh SJ, Tran SH, Hallden G, Kim GS, Bjeldanes LF, Firestone GL.
    J Biol Chem; 1998 Feb 13; 273(7):3838-47. PubMed ID: 9461564
    [Abstract] [Full Text] [Related]

  • 13. Inhibition of Testosterone Aromatization by the Indole-3-carbinol Derivative CTet in CYP19A1-overexpressing MCF-7 Breast Cancer Cells.
    De Santi M, Carloni E, Galluzzi L, Diotallevi A, Lucarini S, Magnani M, Brandi G.
    Anticancer Agents Med Chem; 2015 Feb 13; 15(7):896-904. PubMed ID: 25612679
    [Abstract] [Full Text] [Related]

  • 14. 3,3'-Diindolylmethane negatively regulates Cdc25A and induces a G2/M arrest by modulation of microRNA 21 in human breast cancer cells.
    Jin Y, Zou X, Feng X.
    Anticancer Drugs; 2010 Oct 13; 21(9):814-22. PubMed ID: 20724916
    [Abstract] [Full Text] [Related]

  • 15. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit proliferation of estrogen receptor-negative breast cancer cells by activation of multiple pathways.
    Vanderlaag K, Su Y, Frankel AE, Grage H, Smith R, Khan S, Safe S.
    Breast Cancer Res Treat; 2008 May 13; 109(2):273-83. PubMed ID: 17624585
    [Abstract] [Full Text] [Related]

  • 16. CIP2A is a target of bortezomib in human triple negative breast cancer cells.
    Tseng LM, Liu CY, Chang KC, Chu PY, Shiau CW, Chen KF.
    Breast Cancer Res; 2012 Apr 26; 14(2):R68. PubMed ID: 22537901
    [Abstract] [Full Text] [Related]

  • 17. Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft.
    Saxena R, Fatima I, Chandra V, Blesson CS, Kharkwal G, Hussain MK, Hajela K, Roy BG, Dwivedi A.
    Steroids; 2013 Nov 26; 78(11):1071-86. PubMed ID: 23891847
    [Abstract] [Full Text] [Related]

  • 18. HIV-1 Tat peptide immunoconjugates differentially sensitize breast cancer cells to selected antiproliferative agents that induce the cyclin-dependent kinase inhibitor p21WAF-1/CIP-1.
    Hu M, Wang J, Chen P, Reilly RM.
    Bioconjug Chem; 2006 Nov 26; 17(5):1280-7. PubMed ID: 16984139
    [Abstract] [Full Text] [Related]

  • 19. Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo.
    Gründker C, Föst C, Fister S, Nolte N, Günthert AR, Emons G.
    Breast Cancer Res; 2010 Nov 26; 12(4):R49. PubMed ID: 20630060
    [Abstract] [Full Text] [Related]

  • 20. Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells.
    Choi YH, Yoo YH.
    Oncol Rep; 2012 Dec 26; 28(6):2163-9. PubMed ID: 23023313
    [Abstract] [Full Text] [Related]

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