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Journal Abstract Search

418 related items for PubMed ID: 21435753

  • 21. Design and synthesis of 4-amino-2-phenylquinazolines as novel topoisomerase I inhibitors with molecular modeling.
    Le TN, Yang SH, Khadka DB, Van HT, Cho SH, Kwon Y, Lee ES, Lee KT, Cho WJ.
    Bioorg Med Chem; 2011 Jul 15; 19(14):4399-404. PubMed ID: 21684168
    [Abstract] [Full Text] [Related]

  • 22. Synthesis of novel benzoxanthone analogues as non-Camptothecin topoisomerase I inhibitors.
    Cheng P, Zhu L, Guo W, Liu W, Yao J, Dong G, Zhang Y, Zhuang C, Sheng C, Miao Z, Zhang W.
    J Enzyme Inhib Med Chem; 2012 Jun 15; 27(3):437-42. PubMed ID: 21770860
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  • 25. Substituted 2-arylquinazolinones: Design, synthesis, and evaluation of cytotoxicity and inhibition of topoisomerases.
    Khadka DB, Tran GH, Shin S, Nguyen HT, Cao HT, Zhao C, Jin Y, Van HT, Chau MV, Kwon Y, Le TN, Cho WJ.
    Eur J Med Chem; 2015 Oct 20; 103():69-79. PubMed ID: 26334499
    [Abstract] [Full Text] [Related]

  • 26. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y, Xu X, Sun Y, Wang H, Sun H, You Q.
    Bioorg Med Chem Lett; 2013 May 15; 23(10):2974-8. PubMed ID: 23566520
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  • 27. Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic topoisomerase I and II dual inhibitor.
    Park S, Thapa Magar TB, Kadayat TM, Lee HJ, Bist G, Shrestha A, Lee ES, Kwon Y.
    Eur J Med Chem; 2017 Feb 15; 127():318-333. PubMed ID: 28068603
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  • 28. Topoisomerase I/II inhibition by a novel naphthoquinone containing a modified anthracycline ring system.
    Kennedy S, DiCesare JC, Sheaff RJ.
    Biochem Biophys Res Commun; 2011 Apr 29; 408(1):94-8. PubMed ID: 21458415
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  • 29. Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
    Thapa P, Kadayat TM, Park S, Shin S, Thapa Magar TB, Bist G, Shrestha A, Na Y, Kwon Y, Lee ES.
    Bioorg Chem; 2016 Jun 29; 66():145-59. PubMed ID: 27174797
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  • 30. New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors.
    Luniewski W, Wietrzyk J, Godlewska J, Switalska M, Piskozub M, Peczynska-Czoch W, Kaczmarek L.
    Bioorg Med Chem Lett; 2012 Oct 01; 22(19):6103-7. PubMed ID: 22944121
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  • 32. Boehmeriasin A as new lead compound for the inhibition of topoisomerases and SIRT2.
    Christodoulou MS, Calogero F, Baumann M, García-Argáez AN, Pieraccini S, Sironi M, Dapiaggi F, Bucci R, Broggini G, Gazzola S, Liekens S, Silvani A, Lahtela-Kakkonen M, Martinet N, Nonell-Canals A, Santamaría-Navarro E, Baxendale IR, Dalla Via L, Passarella D.
    Eur J Med Chem; 2015 Mar 06; 92():766-75. PubMed ID: 25626146
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  • 34. Synthesis, cytotoxicity, DNA binding and topoisomerase II inhibition of cassiarin A derivatives.
    Luesakul U, Palaga T, Krusong K, Ngamrojanavanich N, Vilaivan T, Puthong S, Muangsin N.
    Bioorg Med Chem Lett; 2014 Jul 01; 24(13):2845-50. PubMed ID: 24835201
    [Abstract] [Full Text] [Related]

  • 35. Docking studies, synthesis, characterization of some novel oxazine substituted 9-anilinoacridine derivatives and evaluation for their antioxidant and anticancer activities as topoisomerase II inhibitors.
    Kalirajan R, Kulshrestha V, Sankar S, Jubie S.
    Eur J Med Chem; 2012 Oct 01; 56():217-24. PubMed ID: 22982526
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  • 36. Design, synthesis, and structure-activity relationships of new benzofuro[3,2-b]pyridin-7-ols as DNA topoisomerase II inhibitors.
    Shrestha A, Jo H, Kwon Y, Lee ES.
    Bioorg Med Chem Lett; 2018 Feb 15; 28(4):566-571. PubMed ID: 29402741
    [Abstract] [Full Text] [Related]

  • 37. Synthesis, crystal structure and antiproliferative activity of Cu(II) nalidixic acid-DACH conjugate: comparative in vitro DNA/RNA binding profile, cleavage activity and molecular docking studies.
    Arjmand F, Yousuf I, Hadda Tb, Toupet L.
    Eur J Med Chem; 2014 Jun 23; 81():76-88. PubMed ID: 24826817
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  • 38. Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles as a new class of anti-cancer agents.
    Pierce LT, Cahill MM, Winfield HJ, McCarthy FO.
    Eur J Med Chem; 2012 Oct 23; 56():292-300. PubMed ID: 22910137
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  • 39. Potentiation of the antitumor effect of 11-keto-β-boswellic acid by its 3-α-hexanoyloxy derivative.
    Chashoo G, Singh SK, Mondhe DM, Sharma PR, Andotra SS, Shah BA, Taneja SC, Saxena AK.
    Eur J Pharmacol; 2011 Oct 15; 668(3):390-400. PubMed ID: 21821018
    [Abstract] [Full Text] [Related]

  • 40. Molecular modelling design, synthesis and cytotoxic evaluation of certain substituted 2-(3,4,5-triacetoxybenzoylamino)benzo[d]thiazole and 2-(galloylamino)benzo[d]thiazole derivatives having potential topoisomerase-I inhibitory activity.
    Ismail MA, Tratrat C, Haroun MG.
    J Enzyme Inhib Med Chem; 2013 Dec 15; 28(6):1331-45. PubMed ID: 22957723
    [Abstract] [Full Text] [Related]

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