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228 related items for PubMed ID: 21439641

  • 1. 2B4 utilizes ITAM-containing receptor complexes to initiate intracellular signaling and cytolysis.
    Bida AT, Upshaw Neff JL, Dick CJ, Schoon RA, Brickshawana A, Chini CC, Billadeau DD.
    Mol Immunol; 2011 May; 48(9-10):1149-59. PubMed ID: 21439641
    [Abstract] [Full Text] [Related]

  • 2. Molecular dissection of 2B4 signaling: implications for signal transduction by SLAM-related receptors.
    Chen R, Relouzat F, Roncagalli R, Aoukaty A, Tan R, Latour S, Veillette A.
    Mol Cell Biol; 2004 Jun; 24(12):5144-56. PubMed ID: 15169881
    [Abstract] [Full Text] [Related]

  • 3. X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells.
    Parolini S, Bottino C, Falco M, Augugliaro R, Giliani S, Franceschini R, Ochs HD, Wolf H, Bonnefoy JY, Biassoni R, Moretta L, Notarangelo LD, Moretta A.
    J Exp Med; 2000 Aug 07; 192(3):337-46. PubMed ID: 10934222
    [Abstract] [Full Text] [Related]

  • 4. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis.
    Moretta A, Bottino C, Vitale M, Pende D, Cantoni C, Mingari MC, Biassoni R, Moretta L.
    Annu Rev Immunol; 2001 Aug 07; 19():197-223. PubMed ID: 11244035
    [Abstract] [Full Text] [Related]

  • 5. Functional requirement for SAP in 2B4-mediated activation of human natural killer cells as revealed by the X-linked lymphoproliferative syndrome.
    Tangye SG, Phillips JH, Lanier LL, Nichols KE.
    J Immunol; 2000 Sep 15; 165(6):2932-6. PubMed ID: 10975798
    [Abstract] [Full Text] [Related]

  • 6. Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP.
    Tangye SG, Lazetic S, Woollatt E, Sutherland GR, Lanier LL, Phillips JH.
    J Immunol; 1999 Jun 15; 162(12):6981-5. PubMed ID: 10358138
    [Abstract] [Full Text] [Related]

  • 7. Potential pathways for regulation of NK and T cell responses: differential X-linked lymphoproliferative syndrome gene product SAP interactions with SLAM and 2B4.
    Sayós J, Nguyen KB, Wu C, Stepp SE, Howie D, Schatzle JD, Kumar V, Biron CA, Terhorst C.
    Int Immunol; 2000 Dec 15; 12(12):1749-57. PubMed ID: 11099315
    [Abstract] [Full Text] [Related]

  • 8. Molecular basis for positive and negative signaling by the natural killer cell receptor 2B4 (CD244).
    Eissmann P, Beauchamp L, Wooters J, Tilton JC, Long EO, Watzl C.
    Blood; 2005 Jun 15; 105(12):4722-9. PubMed ID: 15713798
    [Abstract] [Full Text] [Related]

  • 9. Dynamic redistribution of the activating 2B4/SAP complex at the cytotoxic NK cell immune synapse.
    Roda-Navarro P, Mittelbrunn M, Ortega M, Howie D, Terhorst C, Sánchez-Madrid F, Fernández-Ruiz E.
    J Immunol; 2004 Sep 15; 173(6):3640-6. PubMed ID: 15356108
    [Abstract] [Full Text] [Related]

  • 10. Role for glycogen synthase kinase-3 in NK cell cytotoxicity and X-linked lymphoproliferative disease.
    Aoukaty A, Tan R.
    J Immunol; 2005 Apr 15; 174(8):4551-8. PubMed ID: 15814676
    [Abstract] [Full Text] [Related]

  • 11. 2B4 (CD244)-mediated activation of cytotoxicity and IFN-gamma release in human NK cells involves distinct pathways.
    Chuang SS, Kumaresan PR, Mathew PA.
    J Immunol; 2001 Dec 01; 167(11):6210-6. PubMed ID: 11714782
    [Abstract] [Full Text] [Related]

  • 12. WhatSAP - 2B4 sends mixed messages in the absence of SAP.
    Watzl C, Claus M.
    Eur J Immunol; 2014 May 01; 44(5):1281-4. PubMed ID: 24659462
    [Abstract] [Full Text] [Related]

  • 13. 2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism.
    Nakajima H, Colonna M.
    Hum Immunol; 2000 Jan 01; 61(1):39-43. PubMed ID: 10658976
    [Abstract] [Full Text] [Related]

  • 14. Association of the X-linked lymphoproliferative disease gene product SAP/SH2D1A with 2B4, a natural killer cell-activating molecule, is dependent on phosphoinositide 3-kinase.
    Aoukaty A, Tan R.
    J Biol Chem; 2002 Apr 12; 277(15):13331-7. PubMed ID: 11815622
    [Abstract] [Full Text] [Related]

  • 15. Redundant role of the Syk protein tyrosine kinase in mouse NK cell differentiation.
    Colucci F, Turner M, Schweighoffer E, Guy-Grand D, Di Bartolo V, Salcedo M, Tybulewicz VL, Di Santo JP.
    J Immunol; 1999 Aug 15; 163(4):1769-74. PubMed ID: 10438908
    [Abstract] [Full Text] [Related]

  • 16. NK cell regulation by SLAM family receptors and SAP-related adapters.
    Veillette A.
    Immunol Rev; 2006 Dec 15; 214():22-34. PubMed ID: 17100873
    [Abstract] [Full Text] [Related]

  • 17. The adaptor 3BP2 activates CD244-mediated cytotoxicity in PKC- and SAP-dependent mechanisms.
    Saborit-Villarroya I, Martinez-Barriocanal A, Oliver-Vila I, Engel P, Sayos J, Martin M.
    Mol Immunol; 2008 Jul 15; 45(12):3446-53. PubMed ID: 18479751
    [Abstract] [Full Text] [Related]

  • 18. SAP controls the cytolytic activity of CD8+ T cells against EBV-infected cells.
    Dupré L, Andolfi G, Tangye SG, Clementi R, Locatelli F, Aricò M, Aiuti A, Roncarolo MG.
    Blood; 2005 Jun 01; 105(11):4383-9. PubMed ID: 15677558
    [Abstract] [Full Text] [Related]

  • 19. Src-dependent Syk activation controls CD69-mediated signaling and function on human NK cells.
    Pisegna S, Zingoni A, Pirozzi G, Cinque B, Cifone MG, Morrone S, Piccoli M, Frati L, Palmieri G, Santoni A.
    J Immunol; 2002 Jul 01; 169(1):68-74. PubMed ID: 12077230
    [Abstract] [Full Text] [Related]

  • 20. The murine NK receptor 2B4 (CD244) exhibits inhibitory function independent of signaling lymphocytic activation molecule-associated protein expression.
    Mooney JM, Klem J, Wülfing C, Mijares LA, Schwartzberg PL, Bennett M, Schatzle JD.
    J Immunol; 2004 Sep 15; 173(6):3953-61. PubMed ID: 15356144
    [Abstract] [Full Text] [Related]

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