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174 related items for PubMed ID: 21448585

  • 1. Wogonin induces apoptosis by activation of ERK and p38 MAPKs signaling pathways and generation of reactive oxygen species in human breast cancer cells.
    Yu JS, Kim AK.
    Mol Cells; 2011 Apr; 31(4):327-35. PubMed ID: 21448585
    [Abstract] [Full Text] [Related]

  • 2. Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway.
    Huang KF, Zhang GD, Huang YQ, Diao Y.
    Int Immunopharmacol; 2012 Feb; 12(2):334-41. PubMed ID: 22182776
    [Abstract] [Full Text] [Related]

  • 3. Butein inhibits the proliferation of breast cancer cells through generation of reactive oxygen species and modulation of ERK and p38 activities.
    Yang LH, Ho YJ, Lin JF, Yeh CW, Kao SH, Hsu LS.
    Mol Med Rep; 2012 Nov; 6(5):1126-32. PubMed ID: 22895548
    [Abstract] [Full Text] [Related]

  • 4. A novel synthetic analog of Militarin, MA-1 induces mitochondrial dependent apoptosis by ROS generation in human lung cancer cells.
    Yoon DH, Lim MH, Lee YR, Sung GH, Lee TH, Jeon BH, Cho JY, Song WO, Park H, Choi S, Kim TW.
    Toxicol Appl Pharmacol; 2013 Dec 15; 273(3):659-71. PubMed ID: 24161344
    [Abstract] [Full Text] [Related]

  • 5. Reactive oxygen species up-regulate p53 and Puma; a possible mechanism for apoptosis during combined treatment with TRAIL and wogonin.
    Lee DH, Rhee JG, Lee YJ.
    Br J Pharmacol; 2009 Aug 15; 157(7):1189-202. PubMed ID: 19438509
    [Abstract] [Full Text] [Related]

  • 6. Cinobufagin induces autophagy-mediated cell death in human osteosarcoma U2OS cells through the ROS/JNK/p38 signaling pathway.
    Ma K, Zhang C, Huang MY, Li WY, Hu GQ.
    Oncol Rep; 2016 Jul 15; 36(1):90-8. PubMed ID: 27176794
    [Abstract] [Full Text] [Related]

  • 7. Toyocamycin induces apoptosis via the crosstalk between reactive oxygen species and p38/ERK MAPKs signaling pathway in human prostate cancer PC-3 cells.
    Park SG, Kim SH, Kim KY, Yu SN, Choi HD, Kim YW, Nam HW, Seo YK, Ahn SC.
    Pharmacol Rep; 2017 Feb 15; 69(1):90-96. PubMed ID: 27912102
    [Abstract] [Full Text] [Related]

  • 8. The synthetic β-nitrostyrene derivative CYT-Rx20 induces breast cancer cell death and autophagy via ROS-mediated MEK/ERK pathway.
    Hung AC, Tsai CH, Hou MF, Chang WL, Wang CH, Lee YC, Ko A, Hu SC, Chang FR, Hsieh PW, Yuan SS.
    Cancer Lett; 2016 Feb 28; 371(2):251-61. PubMed ID: 26683774
    [Abstract] [Full Text] [Related]

  • 9. Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
    Ravindran J, Gupta N, Agrawal M, Bala Bhaskar AS, Lakshmana Rao PV.
    Apoptosis; 2011 Feb 28; 16(2):145-61. PubMed ID: 21082355
    [Abstract] [Full Text] [Related]

  • 10. Wogonin induces reactive oxygen species production and cell apoptosis in human glioma cancer cells.
    Tsai CF, Yeh WL, Huang SM, Tan TW, Lu DY.
    Int J Mol Sci; 2012 Feb 28; 13(8):9877-9892. PubMed ID: 22949836
    [Abstract] [Full Text] [Related]

  • 11. Berberine induces apoptosis in SW620 human colonic carcinoma cells through generation of reactive oxygen species and activation of JNK/p38 MAPK and FasL.
    Hsu WH, Hsieh YS, Kuo HC, Teng CY, Huang HI, Wang CJ, Yang SF, Liou YS, Kuo WH.
    Arch Toxicol; 2007 Oct 28; 81(10):719-28. PubMed ID: 17673978
    [Abstract] [Full Text] [Related]

  • 12. Induction of apoptosis in MDA-MB-231 human breast carcinoma cells with an ethanol extract of Cyperus rotundus L. by activating caspases.
    Park SE, Shin WT, Park C, Hong SH, Kim GY, Kim SO, Ryu CH, Hong SH, Choi YH.
    Oncol Rep; 2014 Dec 28; 32(6):2461-70. PubMed ID: 25241797
    [Abstract] [Full Text] [Related]

  • 13. Reactive oxygen species-mediated phosphorylation of p38 signaling is critically involved in apoptotic effect of Tanshinone I in colon cancer cells.
    Kim DH, Shin EA, Kim B, Shim BS, Kim SH.
    Phytother Res; 2018 Oct 28; 32(10):1975-1982. PubMed ID: 29876988
    [Abstract] [Full Text] [Related]

  • 14. Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease.
    Lee WR, Shen SC, Lin HY, Hou WC, Yang LL, Chen YC.
    Biochem Pharmacol; 2002 Jan 15; 63(2):225-36. PubMed ID: 11841797
    [Abstract] [Full Text] [Related]

  • 15. Hwang-Heuk-San induces apoptosis in HCT116 human colorectal cancer cells through the ROS-mediated activation of caspases and the inactivation of the PI3K/Akt signaling pathway.
    Lee MH, Hong SH, Park C, Kim GY, Leem SH, Choi SH, Keum YS, Hyun JW, Kwon TK, Hong SH, Choi YH.
    Oncol Rep; 2016 Jul 15; 36(1):205-14. PubMed ID: 27221553
    [Abstract] [Full Text] [Related]

  • 16. Deltonin induces apoptosis in MDA‑MB‑231 human breast cancer cells via reactive oxygen species‑mediated mitochondrial dysfunction and ERK/AKT signaling pathways.
    Zhang S, He Y, Tong Q, Chen Q, Wu X, Huang W.
    Mol Med Rep; 2013 Mar 15; 7(3):1038-44. PubMed ID: 23314115
    [Abstract] [Full Text] [Related]

  • 17. Platycodin D induces apoptosis in MCF-7 human breast cancer cells.
    Yu JS, Kim AK.
    J Med Food; 2010 Apr 15; 13(2):298-305. PubMed ID: 20412017
    [Abstract] [Full Text] [Related]

  • 18. A new xanthatin analogue 1β-hydroxyl-5α-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma.
    Fang XY, Zhang H, Zhao L, Tan S, Ren QC, Wang L, Shen XF.
    Biochimie; 2018 Sep 15; 152():43-52. PubMed ID: 29960031
    [Abstract] [Full Text] [Related]

  • 19. Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways.
    Hao W, Yuan X, Yu L, Gao C, Sun X, Wang D, Zheng Q.
    Sci Rep; 2015 May 18; 5():10336. PubMed ID: 25981581
    [Abstract] [Full Text] [Related]

  • 20. Rotenone induces apoptosis in MCF-7 human breast cancer cell-mediated ROS through JNK and p38 signaling.
    Deng YT, Huang HC, Lin JK.
    Mol Carcinog; 2010 Feb 18; 49(2):141-51. PubMed ID: 19777565
    [Abstract] [Full Text] [Related]

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