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293 related items for PubMed ID: 21452327

  • 1. The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice.
    Sekine H, Kinser TT, Qiao F, Martinez E, Paulling E, Ruiz P, Gilkeson GS, Tomlinson S.
    Arthritis Rheum; 2011 Apr; 63(4):1076-85. PubMed ID: 21452327
    [Abstract] [Full Text] [Related]

  • 2. Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
    Atkinson C, Qiao F, Song H, Gilkeson GS, Tomlinson S.
    J Immunol; 2008 Jan 15; 180(2):1231-8. PubMed ID: 18178863
    [Abstract] [Full Text] [Related]

  • 3. The dual role of complement in the progression of renal disease in NZB/W F(1) mice and alternative pathway inhibition.
    Sekine H, Ruiz P, Gilkeson GS, Tomlinson S.
    Mol Immunol; 2011 Oct 15; 49(1-2):317-23. PubMed ID: 22000720
    [Abstract] [Full Text] [Related]

  • 4. Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice.
    Machida T, Sakamoto N, Ishida Y, Takahashi M, Fujita T, Sekine H.
    Front Immunol; 2018 Oct 15; 9():1191. PubMed ID: 29892304
    [Abstract] [Full Text] [Related]

  • 5. Modulation of renal disease in MRL/lpr mice genetically deficient in the alternative complement pathway factor B.
    Watanabe H, Garnier G, Circolo A, Wetsel RA, Ruiz P, Holers VM, Boackle SA, Colten HR, Gilkeson GS.
    J Immunol; 2000 Jan 15; 164(2):786-94. PubMed ID: 10623824
    [Abstract] [Full Text] [Related]

  • 6. Complement component C3 is not required for full expression of immune complex glomerulonephritis in MRL/lpr mice.
    Sekine H, Reilly CM, Molano ID, Garnier G, Circolo A, Ruiz P, Holers VM, Boackle SA, Gilkeson GS.
    J Immunol; 2001 May 15; 166(10):6444-51. PubMed ID: 11342671
    [Abstract] [Full Text] [Related]

  • 7. Administration of a soluble recombinant complement C3 inhibitor protects against renal disease in MRL/lpr mice.
    Bao L, Haas M, Kraus DM, Hack BK, Rakstang JK, Holers VM, Quigg RJ.
    J Am Soc Nephrol; 2003 Mar 15; 14(3):670-9. PubMed ID: 12595503
    [Abstract] [Full Text] [Related]

  • 8. A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.
    Huang Y, Qiao F, Atkinson C, Holers VM, Tomlinson S.
    J Immunol; 2008 Dec 01; 181(11):8068-76. PubMed ID: 19017999
    [Abstract] [Full Text] [Related]

  • 9. Effects of complement factor D deficiency on the renal disease of MRL/lpr mice.
    Elliott MK, Jarmi T, Ruiz P, Xu Y, Holers VM, Gilkeson GS.
    Kidney Int; 2004 Jan 01; 65(1):129-38. PubMed ID: 14675043
    [Abstract] [Full Text] [Related]

  • 10. Targeting the Immune Complex-Bound Complement C3d Ligand as a Novel Therapy for Lupus.
    Kulik L, Laskowski J, Renner B, Woolaver R, Zhang L, Lyubchenko T, You Z, Thurman JM, Holers VM.
    J Immunol; 2019 Dec 15; 203(12):3136-3147. PubMed ID: 31732528
    [Abstract] [Full Text] [Related]

  • 11. The new complement inhibitor CRIg/FH ameliorates lupus nephritis in lupus-prone MRL/lpr mice.
    Shi Y, Yao W, Sun L, Li G, Liu H, Ding P, Hu W, Xu H.
    BMC Nephrol; 2019 Nov 21; 20(1):424. PubMed ID: 31752725
    [Abstract] [Full Text] [Related]

  • 12. Complement factor B inhibitor LNP023 improves lupus nephritis in MRL/lpr mice.
    Chen K, Deng Y, Shang S, Tang L, Li Q, Bai X, Chen X.
    Biomed Pharmacother; 2022 Sep 21; 153():113433. PubMed ID: 36076550
    [Abstract] [Full Text] [Related]

  • 13. A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
    Rohrer B, Long Q, Coughlin B, Wilson RB, Huang Y, Qiao F, Tang PH, Kunchithapautham K, Gilkeson GS, Tomlinson S.
    Invest Ophthalmol Vis Sci; 2009 Jul 21; 50(7):3056-64. PubMed ID: 19264882
    [Abstract] [Full Text] [Related]

  • 14. Efficacy of Targeted Complement Inhibition in Experimental C3 Glomerulopathy.
    Ruseva MM, Peng T, Lasaro MA, Bouchard K, Liu-Chen S, Sun F, Yu ZX, Marozsan A, Wang Y, Pickering MC.
    J Am Soc Nephrol; 2016 Feb 21; 27(2):405-16. PubMed ID: 26047789
    [Abstract] [Full Text] [Related]

  • 15. Absence of functional alternative complement pathway alleviates lupus cerebritis.
    Alexander JJ, Jacob A, Vezina P, Sekine H, Gilkeson GS, Quigg RJ.
    Eur J Immunol; 2007 Jun 21; 37(6):1691-701. PubMed ID: 17523212
    [Abstract] [Full Text] [Related]

  • 16. Complement receptor of the immunoglobulin superfamily reduces murine lupus nephritis and cutaneous disease.
    Lieberman LA, Mizui M, Nalbandian A, Bossé R, Crispín JC, Tsokos GC.
    Clin Immunol; 2015 Oct 21; 160(2):286-91. PubMed ID: 25988858
    [Abstract] [Full Text] [Related]

  • 17. Decrease in glomerulonephritis and Th1-associated autoantibody production after progesterone treatment in NZB/NZW mice.
    Hughes GC, Martin D, Zhang K, Hudkins KL, Alpers CE, Clark EA, Elkon KB.
    Arthritis Rheum; 2009 Jun 21; 60(6):1775-84. PubMed ID: 19479860
    [Abstract] [Full Text] [Related]

  • 18. Activation-induced deaminase-deficient MRL/lpr mice secrete high levels of protective antibodies against lupus nephritis.
    Jiang C, Zhao ML, Scearce RM, Diaz M.
    Arthritis Rheum; 2011 Apr 21; 63(4):1086-96. PubMed ID: 21225690
    [Abstract] [Full Text] [Related]

  • 19. Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement.
    Alawieh A, Elvington A, Zhu H, Yu J, Kindy MS, Atkinson C, Tomlinson S.
    J Neuroinflammation; 2015 Dec 30; 12():247. PubMed ID: 26714866
    [Abstract] [Full Text] [Related]

  • 20. C-reactive protein, immunoglobulin G and complement co-localize in renal immune deposits of proliferative lupus nephritis.
    Sjöwall C, Olin AI, Skogh T, Wetterö J, Mörgelin M, Nived O, Sturfelt G, Bengtsson AA.
    Autoimmunity; 2013 May 30; 46(3):205-14. PubMed ID: 23331132
    [Abstract] [Full Text] [Related]

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