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236 related items for PubMed ID: 21454562
41. Demonstration of a direct interaction between residue 22 in the carboxyl-terminal half of secretin and the amino-terminal tail of the secretin receptor using photoaffinity labeling. Dong M, Wang Y, Pinon DI, Hadac EM, Miller LJ. J Biol Chem; 1999 Jan 08; 274(2):903-9. PubMed ID: 9873030 [Abstract] [Full Text] [Related]
42. Mutational analysis of the glucagon receptor: similarities with the vasoactive intestinal peptide (VIP)/pituitary adenylate cyclase-activating peptide (PACAP)/secretin receptors for recognition of the ligand's third residue. Perret J, Van Craenenbroeck M, Langer I, Vertongen P, Gregoire F, Robberecht P, Waelbroeck M. Biochem J; 2002 Mar 01; 362(Pt 2):389-94. PubMed ID: 11853547 [Abstract] [Full Text] [Related]
43. Roles of specific extracellular domains of the glucagon receptor in ligand binding and signaling. Unson CG, Wu CR, Jiang Y, Yoo B, Cheung C, Sakmar TP, Merrifield RB. Biochemistry; 2002 Oct 01; 41(39):11795-803. PubMed ID: 12269822 [Abstract] [Full Text] [Related]
44. The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1. López de Maturana R, Willshaw A, Kuntzsch A, Rudolph R, Donnelly D. J Biol Chem; 2003 Mar 21; 278(12):10195-200. PubMed ID: 12524435 [Abstract] [Full Text] [Related]
45. Seeking for alpha-helical propensity in a receptor-bound conformation of glucagon-like peptide-1. Murage E, Beinborn M, Ahn JM. Adv Exp Med Biol; 2009 Mar 21; 611():289-90. PubMed ID: 19400196 [No Abstract] [Full Text] [Related]
46. Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in Vitro. Swedberg JE, Schroeder CI, Mitchell JM, Fairlie DP, Edmonds DJ, Griffith DA, Ruggeri RB, Derksen DR, Loria PM, Price DA, Liras S, Craik DJ. J Biol Chem; 2016 Jul 22; 291(30):15778-87. PubMed ID: 27226591 [Abstract] [Full Text] [Related]
47. Differential spatial approximation between cholecystokinin residue 30 and receptor residues in active and inactive conformations. Dong M, Hadac EM, Pinon DI, Miller LJ. Mol Pharmacol; 2005 Jun 22; 67(6):1892-900. PubMed ID: 15774770 [Abstract] [Full Text] [Related]
48. A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors. Al-Sabah S, Donnelly D. Br J Pharmacol; 2003 Sep 22; 140(2):339-46. PubMed ID: 12970080 [Abstract] [Full Text] [Related]
49. Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain. Runge S, Schimmer S, Oschmann J, Schiødt CB, Knudsen SM, Jeppesen CB, Madsen K, Lau J, Thøgersen H, Rudolph R. Biochemistry; 2007 May 15; 46(19):5830-40. PubMed ID: 17444618 [Abstract] [Full Text] [Related]
50. Characterization of glucagon-like peptide 1 receptor (GLP1R) gene in chickens: functional analysis, tissue distribution, and identification of its transcript variants. Huang G, Li J, Fu H, Yan Z, Bu G, He X, Wang Y. Domest Anim Endocrinol; 2012 Jul 15; 43(1):1-15. PubMed ID: 22417644 [Abstract] [Full Text] [Related]
51. Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain. Runge S, Thøgersen H, Madsen K, Lau J, Rudolph R. J Biol Chem; 2008 Apr 25; 283(17):11340-7. PubMed ID: 18287102 [Abstract] [Full Text] [Related]
52. The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation. Estall JL, Koehler JA, Yusta B, Drucker DJ. J Biol Chem; 2005 Jun 10; 280(23):22124-34. PubMed ID: 15817468 [Abstract] [Full Text] [Related]
53. A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures. Wootten D, Reynolds CA, Koole C, Smith KJ, Mobarec JC, Simms J, Quon T, Coudrat T, Furness SG, Miller LJ, Christopoulos A, Sexton PM. Mol Pharmacol; 2016 Mar 10; 89(3):335-47. PubMed ID: 26700562 [Abstract] [Full Text] [Related]
54. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) differentially regulates orthosteric but not allosteric agonist binding and function. Koole C, Wootten D, Simms J, Savage EE, Miller LJ, Christopoulos A, Sexton PM. J Biol Chem; 2012 Feb 03; 287(6):3659-73. PubMed ID: 22147709 [Abstract] [Full Text] [Related]
55. Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket. Mann RJ, Al-Sabah S, de Maturana RL, Sinfield JK, Donnelly D. Peptides; 2010 Dec 03; 31(12):2289-93. PubMed ID: 20869417 [Abstract] [Full Text] [Related]
56. Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity. Runge S, Wulff BS, Madsen K, Bräuner-Osborne H, Knudsen LB. Br J Pharmacol; 2003 Mar 03; 138(5):787-94. PubMed ID: 12642379 [Abstract] [Full Text] [Related]
58. Direct demonstration of unique mode of natural peptide binding to the type 2 cholecystokinin receptor using photoaffinity labeling. Dong M, Miller LJ. Peptides; 2013 Aug 03; 46():143-9. PubMed ID: 23770253 [Abstract] [Full Text] [Related]
59. Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action. Day JW, Li P, Patterson JT, Chabenne J, Chabenne MD, Gelfanov VM, Dimarchi RD. J Pept Sci; 2011 Mar 03; 17(3):218-25. PubMed ID: 21308878 [Abstract] [Full Text] [Related]
60. Transmembrane α-helix 2 and 7 are important for small molecule-mediated activation of the GLP-1 receptor. Rye Underwood C, Møller Knudsen S, Schjellerup Wulff B, Bräuner-Osborne H, Lau J, Knudsen LB, Peters GH, Reedtz-Runge S. Pharmacology; 2011 Mar 03; 88(5-6):340-8. PubMed ID: 22134089 [Abstract] [Full Text] [Related] Page: [Previous] [Next] [New Search]