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204 related items for PubMed ID: 21454579

  • 1. Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation.
    Xiao Z, Wang T, Qin H, Huang C, Feng Y, Xia Y.
    J Biol Chem; 2011 Jun 03; 286(22):20100-8. PubMed ID: 21454579
    [Abstract] [Full Text] [Related]

  • 2. Far-infrared radiation acutely increases nitric oxide production by increasing Ca(2+) mobilization and Ca(2+)/calmodulin-dependent protein kinase II-mediated phosphorylation of endothelial nitric oxide synthase at serine 1179.
    Park JH, Lee S, Cho DH, Park YM, Kang DH, Jo I.
    Biochem Biophys Res Commun; 2013 Jul 12; 436(4):601-6. PubMed ID: 23756809
    [Abstract] [Full Text] [Related]

  • 3. Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.
    Fleming I, Fisslthaler B, Dimmeler S, Kemp BE, Busse R.
    Circ Res; 2001 Jun 08; 88(11):E68-75. PubMed ID: 11397791
    [Abstract] [Full Text] [Related]

  • 4. Protein kinase Cα phosphorylates a novel argininosuccinate synthase site at serine 328 during calcium-dependent stimulation of endothelial nitric-oxide synthase in vascular endothelial cells.
    Haines RJ, Corbin KD, Pendleton LC, Eichler DC.
    J Biol Chem; 2012 Jul 27; 287(31):26168-76. PubMed ID: 22696221
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of MEK/ERK1/2 signalling alters endothelial nitric oxide synthase activity in an agonist-dependent manner.
    Cale JM, Bird IM.
    Biochem J; 2006 Sep 01; 398(2):279-88. PubMed ID: 16716148
    [Abstract] [Full Text] [Related]

  • 6. Akt-dependent phosphorylation of serine 1179 and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase 1/2 cooperatively mediate activation of the endothelial nitric-oxide synthase by hydrogen peroxide.
    Cai H, Li Z, Davis ME, Kanner W, Harrison DG, Dudley SC.
    Mol Pharmacol; 2003 Feb 01; 63(2):325-31. PubMed ID: 12527803
    [Abstract] [Full Text] [Related]

  • 7. Phosphorylation of endothelial nitric-oxide synthase regulates superoxide generation from the enzyme.
    Chen CA, Druhan LJ, Varadharaj S, Chen YR, Zweier JL.
    J Biol Chem; 2008 Oct 03; 283(40):27038-47. PubMed ID: 18622039
    [Abstract] [Full Text] [Related]

  • 8. Endothelial nitric-oxide synthase activation generates an inducible nitric-oxide synthase-like output of nitric oxide in inflamed endothelium.
    Lowry JL, Brovkovych V, Zhang Y, Skidgel RA.
    J Biol Chem; 2013 Feb 08; 288(6):4174-93. PubMed ID: 23255592
    [Abstract] [Full Text] [Related]

  • 9. Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635.
    Michell BJ, Harris MB, Chen ZP, Ju H, Venema VJ, Blackstone MA, Huang W, Venema RC, Kemp BE.
    J Biol Chem; 2002 Nov 01; 277(44):42344-51. PubMed ID: 12171920
    [Abstract] [Full Text] [Related]

  • 10. The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells.
    Joy S, Siow RC, Rowlands DJ, Becker M, Wyatt AW, Aaronson PI, Coen CW, Kallo I, Jacob R, Mann GE.
    J Biol Chem; 2006 Sep 15; 281(37):27335-45. PubMed ID: 16840783
    [Abstract] [Full Text] [Related]

  • 11. L-theanine promotes nitric oxide production in endothelial cells through eNOS phosphorylation.
    Siamwala JH, Dias PM, Majumder S, Joshi MK, Sinkar VP, Banerjee G, Chatterjee S.
    J Nutr Biochem; 2013 Mar 15; 24(3):595-605. PubMed ID: 22819553
    [Abstract] [Full Text] [Related]

  • 12. Featured Article: Differential regulation of endothelial nitric oxide synthase phosphorylation by protease-activated receptors in adult human endothelial cells.
    Tillery LC, Epperson TA, Eguchi S, Motley ED.
    Exp Biol Med (Maywood); 2016 Mar 15; 241(6):569-80. PubMed ID: 26729042
    [Abstract] [Full Text] [Related]

  • 13. Role of eNOS phosphorylation at Ser-116 in regulation of eNOS activity in endothelial cells.
    Li C, Ruan L, Sood SG, Papapetropoulos A, Fulton D, Venema RC.
    Vascul Pharmacol; 2007 Mar 15; 47(5-6):257-64. PubMed ID: 17822962
    [Abstract] [Full Text] [Related]

  • 14. Ginsenoside Rg3 increases nitric oxide production via increases in phosphorylation and expression of endothelial nitric oxide synthase: essential roles of estrogen receptor-dependent PI3-kinase and AMP-activated protein kinase.
    Hien TT, Kim ND, Pokharel YR, Oh SJ, Lee MY, Kang KW.
    Toxicol Appl Pharmacol; 2010 Aug 01; 246(3):171-83. PubMed ID: 20546771
    [Abstract] [Full Text] [Related]

  • 15. c-Jun N-terminal kinase 2 phosphorylates endothelial nitric oxide synthase at serine 116 and regulates nitric oxide production.
    Park JH, Park M, Byun CJ, Jo I.
    Biochem Biophys Res Commun; 2012 Jan 06; 417(1):340-5. PubMed ID: 22155232
    [Abstract] [Full Text] [Related]

  • 16. ADP signaling in vascular endothelial cells: ADP-dependent activation of the endothelial isoform of nitric-oxide synthase requires the expression but not the kinase activity of AMP-activated protein kinase.
    Hess CN, Kou R, Johnson RP, Li GK, Michel T.
    J Biol Chem; 2009 Nov 20; 284(47):32209-24. PubMed ID: 19783664
    [Abstract] [Full Text] [Related]

  • 17. CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axis.
    Hwang S, Lee HJ, Kim G, Won KJ, Park YS, Jo I.
    Free Radic Biol Med; 2015 Dec 20; 89():229-40. PubMed ID: 26393424
    [Abstract] [Full Text] [Related]

  • 18. p38 mitogen-activated protein kinase activates eNOS in endothelial cells by an estrogen receptor alpha-dependent pathway in response to black tea polyphenols.
    Anter E, Chen K, Shapira OM, Karas RH, Keaney JF.
    Circ Res; 2005 May 27; 96(10):1072-8. PubMed ID: 15879307
    [Abstract] [Full Text] [Related]

  • 19. Cyclin-dependent kinase 5 phosphorylates endothelial nitric oxide synthase at serine 116.
    Cho DH, Seo J, Park JH, Jo C, Choi YJ, Soh JW, Jo I.
    Hypertension; 2010 Feb 27; 55(2):345-52. PubMed ID: 20048197
    [Abstract] [Full Text] [Related]

  • 20. Agonist-modulated regulation of AMP-activated protein kinase (AMPK) in endothelial cells. Evidence for an AMPK -> Rac1 -> Akt -> endothelial nitric-oxide synthase pathway.
    Levine YC, Li GK, Michel T.
    J Biol Chem; 2007 Jul 13; 282(28):20351-64. PubMed ID: 17519230
    [Abstract] [Full Text] [Related]

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