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Journal Abstract Search

281 related items for PubMed ID: 21454673

  • 1. Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding.
    Garbers C, Jänner N, Chalaris A, Moss ML, Floss DM, Meyer D, Koch-Nolte F, Rose-John S, Scheller J.
    J Biol Chem; 2011 Apr 29; 286(17):14804-11. PubMed ID: 21454673
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  • 2. Minimal interleukin 6 (IL-6) receptor stalk composition for IL-6 receptor shedding and IL-6 classic signaling.
    Baran P, Nitz R, Grötzinger J, Scheller J, Garbers C.
    J Biol Chem; 2013 May 24; 288(21):14756-68. PubMed ID: 23564454
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  • 3. The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases.
    Garbers C, Monhasery N, Aparicio-Siegmund S, Lokau J, Baran P, Nowell MA, Jones SA, Rose-John S, Scheller J.
    Biochim Biophys Acta; 2014 Sep 24; 1842(9):1485-94. PubMed ID: 24878322
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  • 7. Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.
    Riethmueller S, Ehlers JC, Lokau J, Düsterhöft S, Knittler K, Dombrowsky G, Grötzinger J, Rabe B, Rose-John S, Garbers C.
    Sci Rep; 2016 May 06; 6():25550. PubMed ID: 27151651
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  • 8. Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17.
    Franke M, Schröder J, Monhasery N, Ackfeld T, Hummel TM, Rabe B, Garbers C, Becker-Pauly C, Floss DM, Scheller J.
    J Biol Chem; 2016 May 13; 291(20):10551-61. PubMed ID: 26961870
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  • 9. Involvement of a disintegrin and metalloproteinase 10 and 17 in shedding of tumor necrosis factor-alpha.
    Hikita A, Tanaka N, Yamane S, Ikeda Y, Furukawa H, Tohma S, Suzuki R, Tanaka S, Mitomi H, Fukui N.
    Biochem Cell Biol; 2009 Aug 13; 87(4):581-93. PubMed ID: 19767822
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  • 10. Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.
    Arnold P, Boll I, Rothaug M, Schumacher N, Schmidt F, Wichert R, Schneppenheim J, Lokau J, Pickhinke U, Koudelka T, Tholey A, Rabe B, Scheller J, Lucius R, Garbers C, Rose-John S, Becker-Pauly C.
    Sci Rep; 2017 Mar 09; 7():44053. PubMed ID: 28276471
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  • 11. Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-α shedding.
    Folgosa L, Zellner HB, El Shikh ME, Conrad DH.
    J Immunol; 2013 Dec 15; 191(12):5951-8. PubMed ID: 24227779
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  • 13. The cytoplasmic domain of a disintegrin and metalloproteinase 10 (ADAM10) regulates its constitutive activity but is dispensable for stimulated ADAM10-dependent shedding.
    Maretzky T, Evers A, Le Gall S, Alabi RO, Speck N, Reiss K, Blobel CP.
    J Biol Chem; 2015 Mar 20; 290(12):7416-25. PubMed ID: 25605720
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  • 14. Identification of ADAM10 as a major TNF sheddase in ADAM17-deficient fibroblasts.
    Mezyk-Kopeć R, Bzowska M, Stalińska K, Chełmicki T, Podkalicki M, Jucha J, Kowalczyk K, Mak P, Bereta J.
    Cytokine; 2009 Jun 20; 46(3):309-15. PubMed ID: 19346138
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  • 15. Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules.
    Ludwig A, Hundhausen C, Lambert MH, Broadway N, Andrews RC, Bickett DM, Leesnitzer MA, Becherer JD.
    Comb Chem High Throughput Screen; 2005 Mar 20; 8(2):161-71. PubMed ID: 15777180
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  • 18. T-cell immunoglobulin and mucin domain 2 (TIM-2) is a target of ADAM10-mediated ectodomain shedding.
    Dewitz C, Möller-Hackbarth K, Schweigert O, Reiss K, Chalaris A, Scheller J, Rose-John S.
    FEBS J; 2014 Jan 20; 281(1):157-74. PubMed ID: 24164679
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  • 19. Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.
    Schumacher N, Schmidt S, Schwarz J, Dohr D, Lokau J, Scheller J, Garbers C, Chalaris A, Rose-John S, Rabe B.
    J Immunol; 2016 Nov 01; 197(9):3705-3715. PubMed ID: 27698010
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  • 20. Activation of Toll-like Receptor 2 (TLR2) induces Interleukin-6 trans-signaling.
    Flynn CM, Garbers Y, Lokau J, Wesch D, Schulte DM, Laudes M, Lieb W, Aparicio-Siegmund S, Garbers C.
    Sci Rep; 2019 May 13; 9(1):7306. PubMed ID: 31086276
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