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298 related items for PubMed ID: 21454676

  • 1. Down-regulation of cytokine-induced interleukin-8 requires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosphatase 1-dependent and -independent mechanisms.
    Dauletbaev N, Eklove D, Mawji N, Iskandar M, Di Marco S, Gallouzi IE, Lands LC.
    J Biol Chem; 2011 May 06; 286(18):15998-6007. PubMed ID: 21454676
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of NF-kappaB-dependent transcription by MKP-1: transcriptional repression by glucocorticoids occurring via p38 MAPK.
    King EM, Holden NS, Gong W, Rider CF, Newton R.
    J Biol Chem; 2009 Sep 25; 284(39):26803-15. PubMed ID: 19648110
    [Abstract] [Full Text] [Related]

  • 3. MKP-1: a negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells.
    Manetsch M, Che W, Seidel P, Chen Y, Ammit AJ.
    Cell Signal; 2012 Apr 25; 24(4):907-13. PubMed ID: 22200679
    [Abstract] [Full Text] [Related]

  • 4. Mitogen-activated protein kinase phosphatase-1 negatively regulates the expression of interleukin-6, interleukin-8, and cyclooxygenase-2 in A549 human lung epithelial cells.
    Turpeinen T, Nieminen R, Moilanen E, Korhonen R.
    J Pharmacol Exp Ther; 2010 Apr 25; 333(1):310-8. PubMed ID: 20089808
    [Abstract] [Full Text] [Related]

  • 5. Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumatic drugs.
    Nieminen R, Korhonen R, Moilanen T, Clark AR, Moilanen E.
    Arthritis Rheum; 2010 Jun 25; 62(6):1650-9. PubMed ID: 20178133
    [Abstract] [Full Text] [Related]

  • 6. Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1.
    Quante T, Ng YC, Ramsay EE, Henness S, Allen JC, Parmentier J, Ge Q, Ammit AJ.
    Am J Respir Cell Mol Biol; 2008 Aug 25; 39(2):208-17. PubMed ID: 18314542
    [Abstract] [Full Text] [Related]

  • 7. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.
    Lasa M, Abraham SM, Boucheron C, Saklatvala J, Clark AR.
    Mol Cell Biol; 2002 Nov 25; 22(22):7802-11. PubMed ID: 12391149
    [Abstract] [Full Text] [Related]

  • 8. Suppression of cytokine production by glucocorticoids is mediated by MKP-1 in human lung epithelial cells.
    Keränen T, Moilanen E, Korhonen R.
    Inflamm Res; 2017 May 25; 66(5):441-449. PubMed ID: 28299397
    [Abstract] [Full Text] [Related]

  • 9. Dexamethasone suppresses interleukin-1beta-induced human beta-defensin 2 mRNA expression: involvement of p38 MAPK, JNK, MKP-1, and NF-kappaB transcriptional factor in A549 cells.
    Jang BC, Lim KJ, Suh MH, Park JG, Suh SI.
    FEMS Immunol Med Microbiol; 2007 Oct 25; 51(1):171-84. PubMed ID: 17645739
    [Abstract] [Full Text] [Related]

  • 10. Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1.
    Prabhala P, Bunge K, Rahman MM, Ge Q, Clark AR, Ammit AJ.
    Am J Physiol Lung Cell Mol Physiol; 2015 May 01; 308(9):L973-80. PubMed ID: 25724669
    [Abstract] [Full Text] [Related]

  • 11. Annexin 1 negatively regulates IL-6 expression via effects on p38 MAPK and MAPK phosphatase-1.
    Yang YH, Toh ML, Clyne CD, Leech M, Aeberli D, Xue J, Dacumos A, Sharma L, Morand EF.
    J Immunol; 2006 Dec 01; 177(11):8148-53. PubMed ID: 17114490
    [Abstract] [Full Text] [Related]

  • 12. Corticosteroid inhibition of growth-related oncogene protein-alpha via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells.
    Issa R, Xie S, Khorasani N, Sukkar M, Adcock IM, Lee KY, Chung KF.
    J Immunol; 2007 Jun 01; 178(11):7366-75. PubMed ID: 17513787
    [Abstract] [Full Text] [Related]

  • 13. Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.
    Valente AJ, Yoshida T, Gardner JD, Somanna N, Delafontaine P, Chandrasekar B.
    Cell Signal; 2012 Feb 01; 24(2):560-568. PubMed ID: 22037550
    [Abstract] [Full Text] [Related]

  • 14. Ibuprofen modulates NF-kB activity but not IL-8 production in cystic fibrosis respiratory epithelial cells.
    Dauletbaev N, Lam J, Eklove D, Iskandar M, Lands LC.
    Respiration; 2010 Feb 01; 79(3):234-42. PubMed ID: 19887769
    [Abstract] [Full Text] [Related]

  • 15. Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids.
    Toh ML, Yang Y, Leech M, Santos L, Morand EF.
    Arthritis Rheum; 2004 Oct 01; 50(10):3118-28. PubMed ID: 15476200
    [Abstract] [Full Text] [Related]

  • 16. ANP inhibits TNF-alpha-induced endothelial MCP-1 expression--involvement of p38 MAPK and MKP-1.
    Weber NC, Blumenthal SB, Hartung T, Vollmar AM, Kiemer AK.
    J Leukoc Biol; 2003 Nov 01; 74(5):932-41. PubMed ID: 12960255
    [Abstract] [Full Text] [Related]

  • 17. Strong inhibition of TNF-alpha production and inhibition of IL-8 and COX-2 mRNA expression in monocyte-derived macrophages by RWJ 67657, a p38 mitogen-activated protein kinase (MAPK) inhibitor.
    Westra J, Doornbos-van der Meer B, de Boer P, van Leeuwen MA, van Rijswijk MH, Limburg PC.
    Arthritis Res Ther; 2004 Nov 01; 6(4):R384-92. PubMed ID: 15225374
    [Abstract] [Full Text] [Related]

  • 18. Corticosteroid-Induced MKP-1 Represses Pro-Inflammatory Cytokine Secretion by Enhancing Activity of Tristetraprolin (TTP) in ASM Cells.
    Prabhala P, Bunge K, Ge Q, Ammit AJ.
    J Cell Physiol; 2016 Oct 01; 231(10):2153-8. PubMed ID: 26825339
    [Abstract] [Full Text] [Related]

  • 19. Novel p38 MAPK inhibitor ML3403 has potent anti-inflammatory activity in airway smooth muscle.
    Munoz L, Ramsay EE, Manetsch M, Ge Q, Peifer C, Laufer S, Ammit AJ.
    Eur J Pharmacol; 2010 Jun 10; 635(1-3):212-8. PubMed ID: 20226180
    [Abstract] [Full Text] [Related]

  • 20. Regulation of tristetraprolin expression by mitogen-activated protein kinase phosphatase-1.
    Huotari N, Hömmö T, Taimi V, Nieminen R, Moilanen E, Korhonen R.
    APMIS; 2012 Dec 10; 120(12):988-99. PubMed ID: 23030431
    [Abstract] [Full Text] [Related]

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