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Journal Abstract Search


148 related items for PubMed ID: 21465233

  • 1. Aminopyrimidoisoquinolinequinone (APIQ) redox cycling is potentiated by ascorbate and induces oxidative stress leading to necrotic-like cancer cell death.
    Vásquez DR, Verrax J, Valderrama JA, Calderon PB.
    Invest New Drugs; 2012 Jun; 30(3):1003-11. PubMed ID: 21465233
    [Abstract] [Full Text] [Related]

  • 2. Enhancement of quinone redox cycling by ascorbate induces a caspase-3 independent cell death in human leukaemia cells. An in vitro comparative study.
    Verrax J, Delvaux M, Beghein N, Taper H, Gallez B, Buc Calderon P.
    Free Radic Res; 2005 Jun; 39(6):649-57. PubMed ID: 16036343
    [Abstract] [Full Text] [Related]

  • 3. Role of glycolysis inhibition and poly(ADP-ribose) polymerase activation in necrotic-like cell death caused by ascorbate/menadione-induced oxidative stress in K562 human chronic myelogenous leukemic cells.
    Verrax J, Vanbever S, Stockis J, Taper H, Calderon PB.
    Int J Cancer; 2007 Mar 15; 120(6):1192-7. PubMed ID: 17163414
    [Abstract] [Full Text] [Related]

  • 4. Antiproliferative effects of phenylaminonaphthoquinones are increased by ascorbate and associated with the appearance of a senescent phenotype in human bladder cancer cells.
    Felipe KB, Benites J, Glorieux C, Sid B, Valenzuela M, Kviecinski MR, Pedrosa RC, Valderrama JA, Levêque P, Gallez B, Verrax J, Buc Calderon P.
    Biochem Biophys Res Commun; 2013 Apr 19; 433(4):573-8. PubMed ID: 23523795
    [Abstract] [Full Text] [Related]

  • 5. Ascorbate/menadione-induced oxidative stress kills cancer cells that express normal or mutated forms of the oncogenic protein Bcr-Abl. An in vitro and in vivo mechanistic study.
    Beck R, Pedrosa RC, Dejeans N, Glorieux C, Levêque P, Gallez B, Taper H, Eeckhoudt S, Knoops L, Calderon PB, Verrax J.
    Invest New Drugs; 2011 Oct 19; 29(5):891-900. PubMed ID: 20454833
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of cell proliferation and migration by oxidative stress from ascorbate-driven juglone redox cycling in human bladder-derived T24 cells.
    Kviecinski MR, Pedrosa RC, Felipe KB, Farias MS, Glorieux C, Valenzuela M, Sid B, Benites J, Valderrama JA, Verrax J, Buc Calderon P.
    Biochem Biophys Res Commun; 2012 May 04; 421(2):268-73. PubMed ID: 22507983
    [Abstract] [Full Text] [Related]

  • 7. Oxidative stress by ascorbate/menadione association kills K562 human chronic myelogenous leukaemia cells and inhibits its tumour growth in nude mice.
    Verrax J, Stockis J, Tison A, Taper HS, Calderon PB.
    Biochem Pharmacol; 2006 Sep 14; 72(6):671-80. PubMed ID: 16828058
    [Abstract] [Full Text] [Related]

  • 8. Redox-active quinones and ascorbate: an innovative cancer therapy that exploits the vulnerability of cancer cells to oxidative stress.
    Verrax J, Beck R, Dejeans N, Glorieux C, Sid B, Pedrosa RC, Benites J, Vásquez D, Valderrama JA, Calderon PB.
    Anticancer Agents Med Chem; 2011 Feb 14; 11(2):213-21. PubMed ID: 21395522
    [Abstract] [Full Text] [Related]

  • 9. Intracellular ATP levels determine cell death fate of cancer cells exposed to both standard and redox chemotherapeutic agents.
    Verrax J, Dejeans N, Sid B, Glorieux C, Calderon PB.
    Biochem Pharmacol; 2011 Dec 01; 82(11):1540-8. PubMed ID: 21843513
    [Abstract] [Full Text] [Related]

  • 10. Menadione reduction by pharmacological doses of ascorbate induces an oxidative stress that kills breast cancer cells.
    Beck R, Verrax J, Dejeans N, Taper H, Calderon PB.
    Int J Toxicol; 2009 Dec 01; 28(1):33-42. PubMed ID: 19482829
    [Abstract] [Full Text] [Related]

  • 11. Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis.
    Ma E, Chen P, Wilkins HM, Wang T, Swerdlow RH, Chen Q.
    Free Radic Biol Med; 2017 Dec 01; 113():36-47. PubMed ID: 28916476
    [Abstract] [Full Text] [Related]

  • 12. Caspase inhibition augments Dichlorvos-induced dopaminergic neuronal cell death by increasing ROS production and PARP1 activation.
    Wani WY, Sunkaria A, Sharma DR, Kandimalla RJ, Kaushal A, Gerace E, Chiarugi A, Gill KD.
    Neuroscience; 2014 Jan 31; 258():1-15. PubMed ID: 24231740
    [Abstract] [Full Text] [Related]

  • 13. Ascorbate potentiates the cytotoxicity of menadione leading to an oxidative stress that kills cancer cells by a non-apoptotic caspase-3 independent form of cell death.
    Verrax J, Cadrobbi J, Marques C, Taper H, Habraken Y, Piette J, Calderon PB.
    Apoptosis; 2004 Mar 31; 9(2):223-33. PubMed ID: 15004519
    [Abstract] [Full Text] [Related]

  • 14. Anticancer therapeutic potential of Mn porphyrin/ascorbate system.
    Tovmasyan A, Sampaio RS, Boss MK, Bueno-Janice JC, Bader BH, Thomas M, Reboucas JS, Orr M, Chandler JD, Go YM, Jones DP, Venkatraman TN, Haberle S, Kyui N, Lascola CD, Dewhirst MW, Spasojevic I, Benov L, Batinic-Haberle I.
    Free Radic Biol Med; 2015 Dec 31; 89():1231-47. PubMed ID: 26496207
    [Abstract] [Full Text] [Related]

  • 15. Antimycin A shows selective antiproliferation to oral cancer cells by oxidative stress-mediated apoptosis and DNA damage.
    Yu TJ, Hsieh CY, Tang JY, Lin LC, Huang HW, Wang HR, Yeh YC, Chuang YT, Ou-Yang F, Chang HW.
    Environ Toxicol; 2020 Nov 31; 35(11):1212-1224. PubMed ID: 32662599
    [Abstract] [Full Text] [Related]

  • 16. Alpha-tocopheryl succinate inhibits autophagic survival of prostate cancer cells induced by vitamin K3 and ascorbate to trigger cell death.
    Tomasetti M, Nocchi L, Neuzil J, Goodwin J, Nguyen M, Dong L, Manzella N, Staffolani S, Milanese C, Garrone B, Alleva R, Borghi B, Santarelli L, Guerrieri R.
    PLoS One; 2012 Nov 31; 7(12):e52263. PubMed ID: 23272231
    [Abstract] [Full Text] [Related]

  • 17. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces oxidative stress, DNA strand breaks, and poly(ADP-ribose) polymerase-1 activation in human breast carcinoma cell lines.
    Lin PH, Lin CH, Huang CC, Chuang MC, Lin P.
    Toxicol Lett; 2007 Aug 31; 172(3):146-58. PubMed ID: 17669606
    [Abstract] [Full Text] [Related]

  • 18. Role of redox signaling and poly (adenosine diphosphate-ribose) polymerase activation in vascular smooth muscle cell growth inhibition by nitric oxide and peroxynitrite.
    Huang J, Lin SC, Nadershahi A, Watts SW, Sarkar R.
    J Vasc Surg; 2008 Mar 31; 47(3):599-607. PubMed ID: 18295111
    [Abstract] [Full Text] [Related]

  • 19. Cross talk between poly(ADP-ribose) polymerase 1 methylation and oxidative stress involved in the toxic effect of anatase titanium dioxide nanoparticles.
    Bai W, Chen Y, Gao A.
    Int J Nanomedicine; 2015 Mar 31; 10():5561-9. PubMed ID: 26366077
    [Abstract] [Full Text] [Related]

  • 20. Induction of necrosis in human liver tumor cells by α-phellandrene.
    Hsieh SL, Li YC, Chang WC, Chung JG, Hsieh LC, Wu CC.
    Nutr Cancer; 2014 Mar 31; 66(6):970-9. PubMed ID: 25077527
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