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572 related items for PubMed ID: 21494058

  • 1. Tetramethylpyrazine inhibits hypoxia-induced pulmonary vascular leakage in rats via the ROS-HIF-VEGF pathway.
    Zhang L, Deng M, Zhou S.
    Pharmacology; 2011; 87(5-6):265-73. PubMed ID: 21494058
    [Abstract] [Full Text] [Related]

  • 2. Fluoxetine protects against monocrotaline-induced pulmonary arterial remodeling by inhibition of hypoxia-inducible factor-1α and vascular endothelial growth factor.
    Han DD, Wang Y, Zhang XH, Liu JR, Wang HL.
    Can J Physiol Pharmacol; 2012 Apr; 90(4):445-54. PubMed ID: 22448962
    [Abstract] [Full Text] [Related]

  • 3. A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak.
    Irwin DC, McCord JM, Nozik-Grayck E, Beckly G, Foreman B, Sullivan T, White M, T Crossno J, Bailey D, Flores SC, Majka S, Klemm D, van Patot MC.
    Free Radic Biol Med; 2009 Jul 01; 47(1):55-61. PubMed ID: 19358884
    [Abstract] [Full Text] [Related]

  • 4. [Effects of tetramethylpyrazine on expression of vascular endothelial growth factor and hypoxia-induced factor-1alpha by rat peritoneal macrophages].
    Xu XY, Ye L, Chen G, Feng JD, Chen WH, Hu YY.
    Zhongguo Zhong Yao Za Zhi; 2006 Oct 01; 31(19):1608-11. PubMed ID: 17165586
    [Abstract] [Full Text] [Related]

  • 5. [Relationship between hypoxia-inducible factor-1alpha expression and extracellular signal-regulated kinase in hypoxic-ischemic cortical neurons].
    Zhang L, Qu Y, Zhang X, Yang C, Mao M, Mu D.
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2009 Aug 01; 23(8):954-8. PubMed ID: 19728613
    [Abstract] [Full Text] [Related]

  • 6. Sphingosine kinase 1 pathway is involved in melatonin-induced HIF-1α inactivation in hypoxic PC-3 prostate cancer cells.
    Cho SY, Lee HJ, Jeong SJ, Lee HJ, Kim HS, Chen CY, Lee EO, Kim SH.
    J Pineal Res; 2011 Aug 01; 51(1):87-93. PubMed ID: 21392092
    [Abstract] [Full Text] [Related]

  • 7. Modulating the hypoxia-inducible factor signaling pathway as a therapeutic modality to regulate retinal angiogenesis.
    DeNiro M, Alsmadi O, Al-Mohanna F.
    Exp Eye Res; 2009 Nov 01; 89(5):700-17. PubMed ID: 19580810
    [Abstract] [Full Text] [Related]

  • 8. Vascular endothelial growth factor expression by hyalocytes and its regulation by glucocorticoid.
    Hata Y, Sassa Y, Kita T, Miura M, Kano K, Kawahara S, Arita R, Nakao S, Shih JL, Ishibashi T.
    Br J Ophthalmol; 2008 Nov 01; 92(11):1540-4. PubMed ID: 18952656
    [Abstract] [Full Text] [Related]

  • 9. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.
    Welsh SJ, Bellamy WT, Briehl MM, Powis G.
    Cancer Res; 2002 Sep 01; 62(17):5089-95. PubMed ID: 12208766
    [Abstract] [Full Text] [Related]

  • 10. HIF-1alpha and HIF-2alpha play a central role in stretch-induced but not shear-stress-induced angiogenesis in rat skeletal muscle.
    Milkiewicz M, Doyle JL, Fudalewski T, Ispanovic E, Aghasi M, Haas TL.
    J Physiol; 2007 Sep 01; 583(Pt 2):753-66. PubMed ID: 17627993
    [Abstract] [Full Text] [Related]

  • 11. The relationships among reactive oxygen species, hypoxia-inducible factor 1alpha and cell proliferation in rat pulmonary arterial smooth muscle cells under hypoxia.
    Zhao JP, Zhou ZG, Hu HL, Guo Z, Wang T, Zhen GH, Zhang ZX.
    Sheng Li Xue Bao; 2007 Jun 25; 59(3):319-24. PubMed ID: 17579787
    [Abstract] [Full Text] [Related]

  • 12. Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: role of mitochondrial reactive oxygen species and HIF-1α.
    Correia SC, Santos RX, Cardoso SM, Santos MS, Oliveira CR, Moreira PI.
    Neurobiol Dis; 2012 Jan 25; 45(1):206-18. PubMed ID: 21854848
    [Abstract] [Full Text] [Related]

  • 13. Hypoxia inducible factor-1alpha is increased in ischemic retina: temporal and spatial correlation with VEGF expression.
    Ozaki H, Yu AY, Della N, Ozaki K, Luna JD, Yamada H, Hackett SF, Okamoto N, Zack DJ, Semenza GL, Campochiaro PA.
    Invest Ophthalmol Vis Sci; 1999 Jan 25; 40(1):182-9. PubMed ID: 9888442
    [Abstract] [Full Text] [Related]

  • 14. Cobalt chloride attenuates hypobaric hypoxia induced vascular leakage in rat brain: molecular mechanisms of action of cobalt chloride.
    Kalpana S, Dhananjay S, Anju B, Lilly G, Sai Ram M.
    Toxicol Appl Pharmacol; 2008 Sep 15; 231(3):354-63. PubMed ID: 18635243
    [Abstract] [Full Text] [Related]

  • 15. Tetramethylpyrazine inhibits CoCl2 -induced neurotoxicity through enhancement of Nrf2/GCLc/GSH and suppression of HIF1α/NOX2/ROS pathways.
    Guan D, Su Y, Li Y, Wu C, Meng Y, Peng X, Cui Y.
    J Neurochem; 2015 Aug 15; 134(3):551-65. PubMed ID: 25952107
    [Abstract] [Full Text] [Related]

  • 16. HIF-1α inhibition ameliorates an allergic airway disease via VEGF suppression in bronchial epithelium.
    Kim SR, Lee KS, Park HS, Park SJ, Min KH, Moon H, Puri KD, Lee YC.
    Eur J Immunol; 2010 Oct 15; 40(10):2858-69. PubMed ID: 20827786
    [Abstract] [Full Text] [Related]

  • 17. The involvement of phosphoinositid 3-kinase/Akt pathway in the activation of hypoxia-inducible factor-1alpha in the developing rat brain after hypoxia-ischemia.
    Li L, Qu Y, Mao M, Xiong Y, Mu D.
    Brain Res; 2008 Mar 04; 1197():152-8. PubMed ID: 18241842
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression.
    Yeh WL, Lu DY, Lin CJ, Liou HC, Fu WM.
    Mol Pharmacol; 2007 Aug 04; 72(2):440-9. PubMed ID: 17513385
    [Abstract] [Full Text] [Related]

  • 19. Arsenite induces endothelial cell permeability increase through a reactive oxygen species-vascular endothelial growth factor pathway.
    Bao L, Shi H.
    Chem Res Toxicol; 2010 Nov 15; 23(11):1726-34. PubMed ID: 20954712
    [Abstract] [Full Text] [Related]

  • 20. Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax.
    Ji DB, Zhu MC, Zhu B, Zhu YZ, Li CL, Ye J, Zhu HB.
    J Cardiovasc Pharmacol; 2008 Aug 15; 52(2):191-202. PubMed ID: 18670359
    [Abstract] [Full Text] [Related]

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