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189 related items for PubMed ID: 21501881

  • 1. Complement upregulation and activation on motor neurons and neuromuscular junction in the SOD1 G93A mouse model of familial amyotrophic lateral sclerosis.
    Heurich B, El Idrissi NB, Donev RM, Petri S, Claus P, Neal J, Morgan BP, Ramaglia V.
    J Neuroimmunol; 2011 Jun; 235(1-2):104-9. PubMed ID: 21501881
    [Abstract] [Full Text] [Related]

  • 2. Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
    Bryson JB, Hobbs C, Parsons MJ, Bosch KD, Pandraud A, Walsh FS, Doherty P, Greensmith L.
    Hum Mol Genet; 2012 Sep 01; 21(17):3871-82. PubMed ID: 22678056
    [Abstract] [Full Text] [Related]

  • 3. Subpial delivery of adeno-associated virus 9-synapsin-caveolin-1 (AAV9-SynCav1) preserves motor neuron and neuromuscular junction morphology, motor function, delays disease onset, and extends survival in hSOD1G93A mice.
    Wang S, Ichinomiya T, Savchenko P, Wang D, Sawada A, Li X, Duong T, Li W, Bonds JA, Kim EJ, Miyanohara A, Roth DM, Patel HH, Patel PM, Tadokoro T, Marsala M, Head BP.
    Theranostics; 2022 Sep 01; 12(12):5389-5403. PubMed ID: 35910808
    [Abstract] [Full Text] [Related]

  • 4. Treatment with an antibody directed against Nogo-A delays disease progression in the SOD1G93A mouse model of Amyotrophic lateral sclerosis.
    Bros-Facer V, Krull D, Taylor A, Dick JR, Bates SA, Cleveland MS, Prinjha RK, Greensmith L.
    Hum Mol Genet; 2014 Aug 15; 23(16):4187-200. PubMed ID: 24667415
    [Abstract] [Full Text] [Related]

  • 5. The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis.
    Woodruff TM, Costantini KJ, Crane JW, Atkin JD, Monk PN, Taylor SM, Noakes PG.
    J Immunol; 2008 Dec 15; 181(12):8727-34. PubMed ID: 19050293
    [Abstract] [Full Text] [Related]

  • 6. C1q induction and global complement pathway activation do not contribute to ALS toxicity in mutant SOD1 mice.
    Lobsiger CS, Boillée S, Pozniak C, Khan AM, McAlonis-Downes M, Lewcock JW, Cleveland DW.
    Proc Natl Acad Sci U S A; 2013 Nov 12; 110(46):E4385-92. PubMed ID: 24170856
    [Abstract] [Full Text] [Related]

  • 7. Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex.
    Thomsen GM, Gowing G, Latter J, Chen M, Vit JP, Staggenborg K, Avalos P, Alkaslasi M, Ferraiuolo L, Likhite S, Kaspar BK, Svendsen CN.
    J Neurosci; 2014 Nov 19; 34(47):15587-600. PubMed ID: 25411487
    [Abstract] [Full Text] [Related]

  • 8. Transcriptomic indices of fast and slow disease progression in two mouse models of amyotrophic lateral sclerosis.
    Nardo G, Iennaco R, Fusi N, Heath PR, Marino M, Trolese MC, Ferraiuolo L, Lawrence N, Shaw PJ, Bendotti C.
    Brain; 2013 Nov 19; 136(Pt 11):3305-32. PubMed ID: 24065725
    [Abstract] [Full Text] [Related]

  • 9. Early changes of neuromuscular transmission in the SOD1(G93A) mice model of ALS start long before motor symptoms onset.
    Rocha MC, Pousinha PA, Correia AM, Sebastião AM, Ribeiro JA.
    PLoS One; 2013 Nov 19; 8(9):e73846. PubMed ID: 24040091
    [Abstract] [Full Text] [Related]

  • 10. RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.
    Vallarola A, Sironi F, Tortarolo M, Gatto N, De Gioia R, Pasetto L, De Paola M, Mariani A, Ghosh S, Watson R, Kalmes A, Bonetto V, Bendotti C.
    J Neuroinflammation; 2018 Mar 01; 15(1):65. PubMed ID: 29495962
    [Abstract] [Full Text] [Related]

  • 11. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS).
    Van Dyke JM, Smit-Oistad IM, Macrander C, Krakora D, Meyer MG, Suzuki M.
    Exp Neurol; 2016 Mar 01; 277():275-282. PubMed ID: 26775178
    [Abstract] [Full Text] [Related]

  • 12. Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA.
    Wang J, Xu G, Slunt HH, Gonzales V, Coonfield M, Fromholt D, Copeland NG, Jenkins NA, Borchelt DR.
    Neurobiol Dis; 2005 Dec 01; 20(3):943-52. PubMed ID: 16046140
    [Abstract] [Full Text] [Related]

  • 13. Early upregulation of cytosolic phospholipase A2α in motor neurons is induced by misfolded SOD1 in a mouse model of amyotrophic lateral sclerosis.
    Malada Edelstein YF, Solomonov Y, Hadad N, Alfahel L, Israelson A, Levy R.
    J Neuroinflammation; 2021 Nov 25; 18(1):274. PubMed ID: 34823547
    [Abstract] [Full Text] [Related]

  • 14. Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS.
    Gould TW, Buss RR, Vinsant S, Prevette D, Sun W, Knudson CM, Milligan CE, Oppenheim RW.
    J Neurosci; 2006 Aug 23; 26(34):8774-86. PubMed ID: 16928866
    [Abstract] [Full Text] [Related]

  • 15. Glycoprotein nonmetastatic melanoma protein B ameliorates skeletal muscle lesions in a SOD1G93A mouse model of amyotrophic lateral sclerosis.
    Nagahara Y, Shimazawa M, Tanaka H, Ono Y, Noda Y, Ohuchi K, Tsuruma K, Katsuno M, Sobue G, Hara H.
    J Neurosci Res; 2015 Oct 23; 93(10):1552-66. PubMed ID: 26140698
    [Abstract] [Full Text] [Related]

  • 16. Protein-bound crotonaldehyde accumulates in the spinal cord of superoxide dismutase-1 mutation-associated familial amyotrophic lateral sclerosis and its transgenic mouse model.
    Shibata N, Kawaguchi M, Uchida K, Kakita A, Takahashi H, Nakano R, Fujimura H, Sakoda S, Ihara Y, Nobukuni K, Takehisa Y, Kuroda S, Kokubo Y, Kuzuhara S, Honma T, Mochizuki Y, Mizutani T, Yamada S, Toi S, Sasaki S, Iwata M, Hirano A, Yamamoto T, Kato Y, Sawada T, Kobayashi M.
    Neuropathology; 2007 Feb 23; 27(1):49-61. PubMed ID: 17319283
    [Abstract] [Full Text] [Related]

  • 17. Assessing the role of immuno-proteasomes in a mouse model of familial ALS.
    Puttaparthi K, Van Kaer L, Elliott JL.
    Exp Neurol; 2007 Jul 23; 206(1):53-8. PubMed ID: 17482163
    [Abstract] [Full Text] [Related]

  • 18. Preferential motor unit loss in the SOD1 G93A transgenic mouse model of amyotrophic lateral sclerosis.
    Hegedus J, Putman CT, Tyreman N, Gordon T.
    J Physiol; 2008 Jul 15; 586(14):3337-51. PubMed ID: 18467368
    [Abstract] [Full Text] [Related]

  • 19. Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis.
    Lee JD, Kamaruzaman NA, Fung JN, Taylor SM, Turner BJ, Atkin JD, Woodruff TM, Noakes PG.
    J Neuroinflammation; 2013 Sep 26; 10():119. PubMed ID: 24067070
    [Abstract] [Full Text] [Related]

  • 20. Caspase 6 has a protective role in SOD1(G93A) transgenic mice.
    Hogg MC, Mitchem MR, König HG, Prehn JH.
    Biochim Biophys Acta; 2016 Jun 26; 1862(6):1063-73. PubMed ID: 26976329
    [Abstract] [Full Text] [Related]

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