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352 related items for PubMed ID: 21505048

  • 1. Oleate blocks palmitate-induced abnormal lipid distribution, endoplasmic reticulum expansion and stress, and insulin resistance in skeletal muscle.
    Peng G, Li L, Liu Y, Pu J, Zhang S, Yu J, Zhao J, Liu P.
    Endocrinology; 2011 Jun; 152(6):2206-18. PubMed ID: 21505048
    [Abstract] [Full Text] [Related]

  • 2. Restoring AS160 phosphorylation rescues skeletal muscle insulin resistance and fatty acid oxidation while not reducing intramuscular lipids.
    Alkhateeb H, Chabowski A, Glatz JF, Gurd B, Luiken JJ, Bonen A.
    Am J Physiol Endocrinol Metab; 2009 Nov; 297(5):E1056-66. PubMed ID: 19724017
    [Abstract] [Full Text] [Related]

  • 3. TRAM1 protect HepG2 cells from palmitate induced insulin resistance through ER stress-JNK pathway.
    Tang Z, Zhang W, Wan C, Xu G, Nie X, Zhu X, Xia N, Zhao Y, Wang S, Cui S, Wang C.
    Biochem Biophys Res Commun; 2015 Feb 20; 457(4):578-84. PubMed ID: 25600807
    [Abstract] [Full Text] [Related]

  • 4. Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance.
    Chen X, Xu S, Wei S, Deng Y, Li Y, Yang F, Liu P.
    Sci Rep; 2016 Feb 22; 6():21454. PubMed ID: 26899878
    [Abstract] [Full Text] [Related]

  • 5. Low molecular weight fucoidan improves endoplasmic reticulum stress-reduced insulin sensitivity through AMP-activated protein kinase activation in L6 myotubes and restores lipid homeostasis in a mouse model of type 2 diabetes.
    Jeong YT, Kim YD, Jung YM, Park DC, Lee DS, Ku SK, Li X, Lu Y, Chao GH, Kim KJ, Lee JY, Baek MC, Kang W, Hwang SL, Chang HW.
    Mol Pharmacol; 2013 Jul 22; 84(1):147-57. PubMed ID: 23658008
    [Abstract] [Full Text] [Related]

  • 6. Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism.
    Salvadó L, Coll T, Gómez-Foix AM, Salmerón E, Barroso E, Palomer X, Vázquez-Carrera M.
    Diabetologia; 2013 Jun 22; 56(6):1372-82. PubMed ID: 23460021
    [Abstract] [Full Text] [Related]

  • 7. Reduction in Insulin Mediated ERK Phosphorylation by Palmitate in Liver Cells Is Independent of Fatty Acid Induced ER Stress.
    Mubarak SA, Otaibi AA, Qarni AA, Bakillah A, Iqbal J.
    Nutrients; 2022 Sep 02; 14(17):. PubMed ID: 36079898
    [Abstract] [Full Text] [Related]

  • 8. Oleate dose-dependently regulates palmitate metabolism and insulin signaling in C2C12 myotubes.
    Capel F, Cheraiti N, Acquaviva C, Hénique C, Bertrand-Michel J, Vianey-Saban C, Prip-Buus C, Morio B.
    Biochim Biophys Acta; 2016 Dec 02; 1861(12 Pt A):2000-2010. PubMed ID: 27725263
    [Abstract] [Full Text] [Related]

  • 9. Reduction of endoplasmic reticulum stress using chemical chaperones or Grp78 overexpression does not protect muscle cells from palmitate-induced insulin resistance.
    Rieusset J, Chauvin MA, Durand A, Bravard A, Laugerette F, Michalski MC, Vidal H.
    Biochem Biophys Res Commun; 2012 Jan 06; 417(1):439-45. PubMed ID: 22177958
    [Abstract] [Full Text] [Related]

  • 10. Loss of Egr-1 sensitizes pancreatic β-cells to palmitate-induced ER stress and apoptosis.
    Cheong MW, Kuo LH, Cheng YN, Tsai PJ, Ho LC, Tai HC, Chiu WT, Chen SH, Lu PJ, Shan YS, Chuang LM, Tsai YS.
    J Mol Med (Berl); 2015 Jul 06; 93(7):807-18. PubMed ID: 25737480
    [Abstract] [Full Text] [Related]

  • 11. Saturated, but not n-6 polyunsaturated, fatty acids induce insulin resistance: role of intramuscular accumulation of lipid metabolites.
    Lee JS, Pinnamaneni SK, Eo SJ, Cho IH, Pyo JH, Kim CK, Sinclair AJ, Febbraio MA, Watt MJ.
    J Appl Physiol (1985); 2006 May 06; 100(5):1467-74. PubMed ID: 16357064
    [Abstract] [Full Text] [Related]

  • 12. In vivo and in vitro application of black soybean peptides in the amelioration of endoplasmic reticulum stress and improvement of insulin resistance.
    Jang EH, Ko JH, Ahn CW, Lee HH, Shin JK, Chang SJ, Park CS, Kang JH.
    Life Sci; 2010 Feb 13; 86(7-8):267-74. PubMed ID: 20045417
    [Abstract] [Full Text] [Related]

  • 13. Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes.
    Guo W, Wong S, Xie W, Lei T, Luo Z.
    Am J Physiol Endocrinol Metab; 2007 Aug 13; 293(2):E576-86. PubMed ID: 17519282
    [Abstract] [Full Text] [Related]

  • 14. Lipid-induced endoplasmic reticulum stress in liver cells results in two distinct outcomes: adaptation with enhanced insulin signaling or insulin resistance.
    Achard CS, Laybutt DR.
    Endocrinology; 2012 May 13; 153(5):2164-77. PubMed ID: 22374970
    [Abstract] [Full Text] [Related]

  • 15. IRE1α and TRB3 do not contribute to the disruption of proximal insulin signaling caused by palmitate in C2C12 myotubes.
    Pierre N, Fernández-Verdejo R, Regnier P, Vanmechelen S, Demeulder B, Francaux M.
    Cell Biol Int; 2016 Jan 13; 40(1):91-9. PubMed ID: 26337904
    [Abstract] [Full Text] [Related]

  • 16. Melatonin inhibits tunicamycin-induced endoplasmic reticulum stress and insulin resistance in skeletal muscle cells.
    Quan X, Wang J, Liang C, Zheng H, Zhang L.
    Biochem Biophys Res Commun; 2015 Aug 07; 463(4):1102-7. PubMed ID: 26079879
    [Abstract] [Full Text] [Related]

  • 17. Lipid metabolism in human skeletal muscle cells: effects of palmitate and chronic hyperglycaemia.
    Aas V, Rokling-Andersen M, Wensaas AJ, Thoresen GH, Kase ET, Rustan AC.
    Acta Physiol Scand; 2005 Jan 07; 183(1):31-41. PubMed ID: 15654918
    [Abstract] [Full Text] [Related]

  • 18. Oleic acid protects insulin-secreting INS-1E cells against palmitic acid-induced lipotoxicity along with an amelioration of ER stress.
    Liu X, Zeng X, Chen X, Luo R, Li L, Wang C, Liu J, Cheng J, Lu Y, Chen Y.
    Endocrine; 2019 Jun 07; 64(3):512-524. PubMed ID: 30778898
    [Abstract] [Full Text] [Related]

  • 19. Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase.
    Bakke SS, Moro C, Nikolić N, Hessvik NP, Badin PM, Lauvhaug L, Fredriksson K, Hesselink MK, Boekschoten MV, Kersten S, Gaster M, Thoresen GH, Rustan AC.
    Biochim Biophys Acta; 2012 Oct 07; 1821(10):1323-33. PubMed ID: 22796147
    [Abstract] [Full Text] [Related]

  • 20. Palmitate contributes to insulin resistance through downregulation of the Src-mediated phosphorylation of Akt in C2C12 myotubes.
    Feng XT, Wang TZ, Leng J, Chen Y, Liu JB, Liu Y, Wang WJ.
    Biosci Biotechnol Biochem; 2012 Oct 07; 76(7):1356-61. PubMed ID: 22785470
    [Abstract] [Full Text] [Related]


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