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184 related items for PubMed ID: 21507987

  • 1. Detoxification: a novel function of BRCA1 in tumor suppression?
    Kang HJ, Hong YB, Kim HJ, Rodriguez OC, Nath RG, Tilli EM, Albanese C, Chung FL, Kwon SH, Bae I.
    Toxicol Sci; 2011 Jul; 122(1):26-37. PubMed ID: 21507987
    [Abstract] [Full Text] [Related]

  • 2. Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene.
    Hamouchene H, Arlt VM, Giddings I, Phillips DH.
    BMC Genomics; 2011 Jun 29; 12():333. PubMed ID: 21714911
    [Abstract] [Full Text] [Related]

  • 3. Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene.
    Harrigan JA, McGarrigle BP, Sutter TR, Olson JR.
    Toxicol In Vitro; 2006 Jun 29; 20(4):426-38. PubMed ID: 16198082
    [Abstract] [Full Text] [Related]

  • 4. Benzo[a]pyrene-induced toxicity: paradoxical protection in Cyp1a1(-/-) knockout mice having increased hepatic BaP-DNA adduct levels.
    Uno S, Dalton TP, Shertzer HG, Genter MB, Warshawsky D, Talaska G, Nebert DW.
    Biochem Biophys Res Commun; 2001 Dec 21; 289(5):1049-56. PubMed ID: 11741297
    [Abstract] [Full Text] [Related]

  • 5. Overexpression of Cu/Zn-superoxide dismutase and/or catalase accelerates benzo(a)pyrene detoxification by upregulation of the aryl hydrocarbon receptor in mouse endothelial cells.
    Wang Z, Yang H, Ramesh A, Roberts LJ, Zhou L, Lin X, Zhao Y, Guo Z.
    Free Radic Biol Med; 2009 Oct 15; 47(8):1221-9. PubMed ID: 19666105
    [Abstract] [Full Text] [Related]

  • 6. Inhibition of aryl hydrocarbon receptor transactivation and DNA adduct formation by CYP1 isoform-selective metabolic deactivation of benzo[a]pyrene.
    Endo K, Uno S, Seki T, Ariga T, Kusumi Y, Mitsumata M, Yamada S, Makishima M.
    Toxicol Appl Pharmacol; 2008 Jul 15; 230(2):135-43. PubMed ID: 18372000
    [Abstract] [Full Text] [Related]

  • 7. Benzo[a]pyrene and tumor necrosis factor-α coordinately increase genotoxic damage and the production of proinflammatory mediators in alveolar epithelial type II cells.
    Umannová L, Machala M, Topinka J, Schmuczerová J, Krčmář P, Neča J, Šujanová K, Kozubík A, Vondráček J.
    Toxicol Lett; 2011 Oct 10; 206(2):121-9. PubMed ID: 21745554
    [Abstract] [Full Text] [Related]

  • 8. Influence of TCDD and natural Ah receptor agonists on benzo[a]pyrene-DNA adduct formation in the Caco-2 human colon cell line.
    de Waard PW, de Kok TM, Maas LM, Peijnenburg AA, Hoogenboom RL, Aarts JM, van Schooten FJ.
    Mutagenesis; 2008 Jan 10; 23(1):67-73. PubMed ID: 18065724
    [Abstract] [Full Text] [Related]

  • 9. Inhibitory effects of chrysoeriol on DNA adduct formation with benzo[a]pyrene in MCF-7 breast cancer cells.
    Takemura H, Nagayoshi H, Matsuda T, Sakakibara H, Morita M, Matsui A, Ohura T, Shimoi K.
    Toxicology; 2010 Jan 10; 274(1-3):42-8. PubMed ID: 20553787
    [Abstract] [Full Text] [Related]

  • 10. Genetic polymorphisms in catalase and CYP1B1 determine DNA adduct formation by benzo(a)pyrene ex vivo.
    Schults MA, Chiu RK, Nagle PW, Wilms LC, Kleinjans JC, van Schooten FJ, Godschalk RW.
    Mutagenesis; 2013 Mar 10; 28(2):181-5. PubMed ID: 23325794
    [Abstract] [Full Text] [Related]

  • 11. A novel in vitro pancreatic carcinogenesis model.
    Kang HJ, Hong YB, Kim HJ, Yi YW, Nath RG, Chang YS, Cho HC, Bae I.
    Toxicol Lett; 2011 Apr 10; 202(1):15-22. PubMed ID: 21256203
    [Abstract] [Full Text] [Related]

  • 12. Hypoxia diminishes the detoxification of the environmental mutagen benzo[a]pyrene.
    Schults MA, Sanen K, Godschalk RW, Theys J, van Schooten FJ, Chiu RK.
    Mutagenesis; 2014 Nov 10; 29(6):481-7. PubMed ID: 25199627
    [Abstract] [Full Text] [Related]

  • 13. Diminished carcinogen detoxification is a novel mechanism for hypoxia-inducible factor 1-mediated genetic instability.
    Schults MA, Timmermans L, Godschalk RW, Theys J, Wouters BG, van Schooten FJ, Chiu RK.
    J Biol Chem; 2010 May 07; 285(19):14558-64. PubMed ID: 20228066
    [Abstract] [Full Text] [Related]

  • 14. Alteration of benzo(a)pyrene biotransformation by resveratrol in ApcMin/+ mouse model of colon carcinogenesis.
    Huderson AC, Rekha Devi PV, Niaz MS, Adunyah SE, Ramesh A.
    Invest New Drugs; 2019 Apr 07; 37(2):238-251. PubMed ID: 29931584
    [Abstract] [Full Text] [Related]

  • 15. Oral benzo[a]pyrene: understanding pharmacokinetics, detoxication, and consequences--Cyp1 knockout mouse lines as a paradigm.
    Nebert DW, Shi Z, Gálvez-Peralta M, Uno S, Dragin N.
    Mol Pharmacol; 2013 Sep 07; 84(3):304-13. PubMed ID: 23761301
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of β-catenin signalling promotes DNA damage elicited by benzo[a]pyrene in a model of human colon cancer cells via CYP1 deregulation.
    Kabátková M, Zapletal O, Tylichová Z, Neča J, Machala M, Milcová A, Topinka J, Kozubík A, Vondráček J.
    Mutagenesis; 2015 Jul 07; 30(4):565-76. PubMed ID: 25805023
    [Abstract] [Full Text] [Related]

  • 17. DNA adduct formation in precision-cut rat liver and lung slices exposed to benzo[a]pyrene.
    Harrigan JA, Vezina CM, McGarrigle BP, Ersing N, Box HC, Maccubbin AE, Olson JR.
    Toxicol Sci; 2004 Feb 07; 77(2):307-14. PubMed ID: 14691214
    [Abstract] [Full Text] [Related]

  • 18. Pregnane X receptor regulates the AhR/Cyp1A1 pathway and protects liver cells from benzo-[α]-pyrene-induced DNA damage.
    Cui H, Gu X, Chen J, Xie Y, Ke S, Wu J, Golovko A, Morpurgo B, Yan C, Phillips TD, Xie W, Luo J, Zhou Z, Tian Y.
    Toxicol Lett; 2017 Jun 05; 275():67-76. PubMed ID: 28428138
    [Abstract] [Full Text] [Related]

  • 19. AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines.
    Hockley SL, Arlt VM, Brewer D, Te Poele R, Workman P, Giddings I, Phillips DH.
    Chem Res Toxicol; 2007 Dec 05; 20(12):1797-810. PubMed ID: 17944540
    [Abstract] [Full Text] [Related]

  • 20. The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene.
    Einem Lindeman T, Poirier MC, Divi RL.
    Mutagenesis; 2011 Sep 05; 26(5):629-35. PubMed ID: 21669939
    [Abstract] [Full Text] [Related]

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