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Journal Abstract Search

63 related items for PubMed ID: 21514282

  • 1. γ-Secretase-mediated growth hormone receptor proteolysis: mapping of the intramembranous cleavage site.
    Wang X, Cowan JW, Gerhart M, Zelickson BR, Jiang J, He K, Wolfe MS, Black RA, Frank SJ.
    Biochem Biophys Res Commun; 2011 May 13; 408(3):432-6. PubMed ID: 21514282
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  • 2. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S, Sunyach C, Checler F.
    J Neurochem; 2006 May 13; 97(3):807-17. PubMed ID: 16524370
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  • 3. Reduced proteolysis of rabbit growth hormone (GH) receptor substituted with mouse GH receptor cleavage site.
    Wang X, He K, Gerhart M, Jiang J, Paxton RJ, Menon RK, Black RA, Baumann G, Frank SJ.
    Mol Endocrinol; 2003 Oct 13; 17(10):1931-43. PubMed ID: 12829808
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  • 6. Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage.
    Cowan JW, Wang X, Guan R, He K, Jiang J, Baumann G, Black RA, Wolfe MS, Frank SJ.
    J Biol Chem; 2005 May 13; 280(19):19331-42. PubMed ID: 15743767
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  • 7. Identification of a region critical for proteolysis of the human growth hormone receptor.
    Conte F, Salles JP, Raynal P, Fernandez L, Molinas C, Tauber M, Bieth E.
    Biochem Biophys Res Commun; 2002 Jan 18; 290(2):851-7. PubMed ID: 11785980
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  • 9. Palmitoylation of the C-terminal fragment of p75(NTR) regulates death signaling and is required for subsequent cleavage by gamma-secretase.
    Underwood CK, Reid K, May LM, Bartlett PF, Coulson EJ.
    Mol Cell Neurosci; 2008 Feb 18; 37(2):346-58. PubMed ID: 18055214
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  • 11. Metalloprotease-mediated GH receptor proteolysis and GHBP shedding. Determination of extracellular domain stem region cleavage site.
    Wang X, He K, Gerhart M, Huang Y, Jiang J, Paxton RJ, Yang S, Lu C, Menon RK, Black RA, Baumann G, Frank SJ.
    J Biol Chem; 2002 Dec 27; 277(52):50510-9. PubMed ID: 12403792
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  • 12. Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.
    Fukumori A, Okochi M, Tagami S, Jiang J, Itoh N, Nakayama T, Yanagida K, Ishizuka-Katsura Y, Morihara T, Kamino K, Tanaka T, Kudo T, Tanii H, Ikuta A, Haass C, Takeda M.
    Biochemistry; 2006 Apr 18; 45(15):4907-14. PubMed ID: 16605258
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  • 13. The insulin-like growth factor 1 (IGF-1) receptor is a substrate for gamma-secretase-mediated intramembrane proteolysis.
    McElroy B, Powell JC, McCarthy JV.
    Biochem Biophys Res Commun; 2007 Jul 13; 358(4):1136-41. PubMed ID: 17524361
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  • 14. Substrate determinants in the C99 juxtamembrane domains differentially affect γ-secretase cleavage specificity and modulator pharmacology.
    Ousson S, Saric A, Baguet A, Losberger C, Genoud S, Vilbois F, Permanne B, Hussain I, Beher D.
    J Neurochem; 2013 May 13; 125(4):610-9. PubMed ID: 23253155
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  • 18. Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop?
    Knappenberger KS, Tian G, Ye X, Sobotka-Briner C, Ghanekar SV, Greenberg BD, Scott CW.
    Biochemistry; 2004 May 25; 43(20):6208-18. PubMed ID: 15147205
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  • 19. Requirement for small side chain residues within the GxGD-motif of presenilin for gamma-secretase substrate cleavage.
    Pérez-Revuelta BI, Fukumori A, Lammich S, Yamasaki A, Haass C, Steiner H.
    J Neurochem; 2010 Feb 25; 112(4):940-50. PubMed ID: 20021564
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  • 20. Generation of intracellular domain of insulin receptor tyrosine kinase by gamma-secretase.
    Kasuga K, Kaneko H, Nishizawa M, Onodera O, Ikeuchi T.
    Biochem Biophys Res Commun; 2007 Aug 17; 360(1):90-6. PubMed ID: 17577576
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