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Journal Abstract Search

703 related items for PubMed ID: 21515057

  • 1. Sulfonamides incorporating 1,3,5-triazine moieties selectively and potently inhibit carbonic anhydrase transmembrane isoforms IX, XII and XIV over cytosolic isoforms I and II: Solution and X-ray crystallographic studies.
    Carta F, Garaj V, Maresca A, Wagner J, Avvaru BS, Robbins AH, Scozzafava A, McKenna R, Supuran CT.
    Bioorg Med Chem; 2011 May 15; 19(10):3105-19. PubMed ID: 21515057
    [Abstract] [Full Text] [Related]

  • 2. Inhibition of human carbonic anhydrase isoforms I-XIV with sulfonamides incorporating fluorine and 1,3,5-triazine moieties.
    Ceruso M, Vullo D, Scozzafava A, Supuran CT.
    Bioorg Med Chem; 2013 Nov 15; 21(22):6929-36. PubMed ID: 24103430
    [Abstract] [Full Text] [Related]

  • 3. Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.
    Garaj V, Puccetti L, Fasolis G, Winum JY, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT.
    Bioorg Med Chem Lett; 2005 Jun 15; 15(12):3102-8. PubMed ID: 15905091
    [Abstract] [Full Text] [Related]

  • 4. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.
    Garaj V, Puccetti L, Fasolis G, Winum JY, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5427-33. PubMed ID: 15454239
    [Abstract] [Full Text] [Related]

  • 5. Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
    Knaus EE, Innocenti A, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2011 Oct 01; 21(19):5892-6. PubMed ID: 21852133
    [Abstract] [Full Text] [Related]

  • 6. Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.
    Güzel O, Innocenti A, Scozzafava A, Salman A, Supuran CT.
    Bioorg Med Chem; 2009 Jul 15; 17(14):4894-9. PubMed ID: 19539481
    [Abstract] [Full Text] [Related]

  • 7. Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.
    Puccetti L, Fasolis G, Vullo D, Chohan ZH, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2005 Jun 15; 15(12):3096-101. PubMed ID: 15908204
    [Abstract] [Full Text] [Related]

  • 8. Carbonic anhydrase inhibitors. Interaction of 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.
    Güzel O, Temperini C, Innocenti A, Scozzafava A, Salman A, Supuran CT.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):152-8. PubMed ID: 18024029
    [Abstract] [Full Text] [Related]

  • 9. New chemotypes acting as isozyme-selective carbonic anhydrase inhibitors with low affinity for the offtarget cytosolic isoform II.
    Carta F, Vullo D, Maresca A, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2012 Mar 15; 22(6):2182-5. PubMed ID: 22365761
    [Abstract] [Full Text] [Related]

  • 10. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.
    Cecchi A, Winum JY, Innocenti A, Vullo D, Montero JL, Scozzafava A, Supuran CT.
    Bioorg Med Chem Lett; 2004 Dec 06; 14(23):5775-80. PubMed ID: 15501039
    [Abstract] [Full Text] [Related]

  • 11. Carbonic anhydrase inhibitors. Sulfonamide diuretics revisited--old leads for new applications?
    Temperini C, Cecchi A, Scozzafava A, Supuran CT.
    Org Biomol Chem; 2008 Jul 21; 6(14):2499-506. PubMed ID: 18600270
    [Abstract] [Full Text] [Related]

  • 12. Carbonic anhydrase inhibitors. Inhibition of isoforms I, II, IV, VA, VII, IX, and XIV with sulfonamides incorporating fructopyranose-thioureido tails.
    Winum JY, Thiry A, Cheikh KE, Dogné JM, Montero JL, Vullo D, Scozzafava A, Masereel B, Supuran CT.
    Bioorg Med Chem Lett; 2007 May 15; 17(10):2685-91. PubMed ID: 17376683
    [Abstract] [Full Text] [Related]

  • 13. 4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII.
    Sūdžius J, Baranauskienė L, Golovenko D, Matulienė J, Michailovienė V, Torresan J, Jachno J, Sukackaitė R, Manakova E, Gražulis S, Tumkevičius S, Matulis D.
    Bioorg Med Chem; 2010 Nov 01; 18(21):7413-21. PubMed ID: 20889345
    [Abstract] [Full Text] [Related]

  • 14. Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
    Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT.
    Bioorg Med Chem; 2008 Apr 01; 16(7):3933-40. PubMed ID: 18242998
    [Abstract] [Full Text] [Related]

  • 15. Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
    Żołnowska B, Sławiński J, Pogorzelska A, Chojnacki J, Vullo D, Supuran CT.
    Eur J Med Chem; 2014 Jan 01; 71():135-47. PubMed ID: 24291567
    [Abstract] [Full Text] [Related]

  • 16. Synthesis of 6-tetrazolyl-substituted sulfocoumarins acting as highly potent and selective inhibitors of the tumor-associated carbonic anhydrase isoforms IX and XII.
    Grandane A, Tanc M, Zalubovskis R, Supuran CT.
    Bioorg Med Chem; 2014 Mar 01; 22(5):1522-8. PubMed ID: 24513186
    [Abstract] [Full Text] [Related]

  • 17. Carbonic anhydrase inhibitors. Interaction of 2-N,N-dimethylamino-1,3,4-thiadiazole-5-methanesulfonamide with 12 mammalian isoforms: kinetic and X-ray crystallographic studies.
    Temperini C, Cecchi A, Boyle NA, Scozzafava A, Cabeza JE, Wentworth P, Blackburn GM, Supuran CT.
    Bioorg Med Chem Lett; 2008 Feb 01; 18(3):999-1005. PubMed ID: 18162396
    [Abstract] [Full Text] [Related]

  • 18. Carbonic anhydrase inhibitors. Diazenylbenzenesulfonamides are potent and selective inhibitors of the tumor-associated isozymes IX and XII over the cytosolic isoforms I and II.
    Carta F, Maresca A, Scozzafava A, Vullo D, Supuran CT.
    Bioorg Med Chem; 2009 Oct 15; 17(20):7093-9. PubMed ID: 19773173
    [Abstract] [Full Text] [Related]

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  • 20. Substituted benzene sulfonamides incorporating 1,3,5-triazinyl moieties potently inhibit human carbonic anhydrases II, IX and XII.
    Saluja AK, Tiwari M, Vullo D, Supuran CT.
    Bioorg Med Chem Lett; 2014 Mar 01; 24(5):1310-4. PubMed ID: 24507918
    [Abstract] [Full Text] [Related]

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