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427 related items for PubMed ID: 21518729

  • 1. ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance.
    Millour J, de Olano N, Horimoto Y, Monteiro LJ, Langer JK, Aligue R, Hajji N, Lam EW.
    Mol Cancer Ther; 2011 Jun; 10(6):1046-58. PubMed ID: 21518729
    [Abstract] [Full Text] [Related]

  • 2. FOXM1 targets NBS1 to regulate DNA damage-induced senescence and epirubicin resistance.
    Khongkow P, Karunarathna U, Khongkow M, Gong C, Gomes AR, Yagüe E, Monteiro LJ, Kongsema M, Zona S, Man EP, Tsang JW, Coombes RC, Wu KJ, Khoo US, Medema RH, Freire R, Lam EW.
    Oncogene; 2014 Aug 07; 33(32):4144-55. PubMed ID: 24141789
    [Abstract] [Full Text] [Related]

  • 3. The Forkhead Box M1 protein regulates BRIP1 expression and DNA damage repair in epirubicin treatment.
    Monteiro LJ, Khongkow P, Kongsema M, Morris JR, Man C, Weekes D, Koo CY, Gomes AR, Pinto PH, Varghese V, Kenny LM, Charles Coombes R, Freire R, Medema RH, Lam EW.
    Oncogene; 2013 Sep 26; 32(39):4634-45. PubMed ID: 23108394
    [Abstract] [Full Text] [Related]

  • 4. The p38 MAPK-MK2 axis regulates E2F1 and FOXM1 expression after epirubicin treatment.
    de Olano N, Koo CY, Monteiro LJ, Pinto PH, Gomes AR, Aligue R, Lam EW.
    Mol Cancer Res; 2012 Sep 26; 10(9):1189-202. PubMed ID: 22802261
    [Abstract] [Full Text] [Related]

  • 5. OTUB1 inhibits the ubiquitination and degradation of FOXM1 in breast cancer and epirubicin resistance.
    Karunarathna U, Kongsema M, Zona S, Gong C, Cabrera E, Gomes AR, Man EP, Khongkow P, Tsang JW, Khoo US, Medema RH, Freire R, Lam EW.
    Oncogene; 2016 Mar 17; 35(11):1433-44. PubMed ID: 26148240
    [Abstract] [Full Text] [Related]

  • 6. FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance.
    Millour J, Constantinidou D, Stavropoulou AV, Wilson MS, Myatt SS, Kwok JM, Sivanandan K, Coombes RC, Medema RH, Hartman J, Lykkesfeldt AE, Lam EW.
    Oncogene; 2010 May 20; 29(20):2983-95. PubMed ID: 20208560
    [Abstract] [Full Text] [Related]

  • 7. Low expression levels of ATM may substitute for CHEK2 /TP53 mutations predicting resistance towards anthracycline and mitomycin chemotherapy in breast cancer.
    Knappskog S, Chrisanthar R, Løkkevik E, Anker G, Østenstad B, Lundgren S, Risberg T, Mjaaland I, Leirvaag B, Miletic H, Lønning PE.
    Breast Cancer Res; 2012 Mar 15; 14(2):R47. PubMed ID: 22420423
    [Abstract] [Full Text] [Related]

  • 8. Gefitinib (Iressa) represses FOXM1 expression via FOXO3a in breast cancer.
    McGovern UB, Francis RE, Peck B, Guest SK, Wang J, Myatt SS, Krol J, Kwok JM, Polychronis A, Coombes RC, Lam EW.
    Mol Cancer Ther; 2009 Mar 15; 8(3):582-91. PubMed ID: 19276163
    [Abstract] [Full Text] [Related]

  • 9. E2F1-mediated transcriptional inhibition of the plasminogen activator inhibitor type 1 gene.
    Koziczak M, Müller H, Helin K, Nagamine Y.
    Eur J Biochem; 2001 Sep 15; 268(18):4969-78. PubMed ID: 11559366
    [Abstract] [Full Text] [Related]

  • 10. FOXM1 confers acquired cisplatin resistance in breast cancer cells.
    Kwok JM, Peck B, Monteiro LJ, Schwenen HD, Millour J, Coombes RC, Myatt SS, Lam EW.
    Mol Cancer Res; 2010 Jan 15; 8(1):24-34. PubMed ID: 20068070
    [Abstract] [Full Text] [Related]

  • 11. p53 inactivation upregulates p73 expression through E2F-1 mediated transcription.
    Tophkhane C, Yang SH, Jiang Y, Ma Z, Subramaniam D, Anant S, Yogosawa S, Sakai T, Liu WG, Edgerton S, Thor A, Yang X.
    PLoS One; 2012 Jan 15; 7(8):e43564. PubMed ID: 22952705
    [Abstract] [Full Text] [Related]

  • 12. E2F1 uses the ATM signaling pathway to induce p53 and Chk2 phosphorylation and apoptosis.
    Powers JT, Hong S, Mayhew CN, Rogers PM, Knudsen ES, Johnson DG.
    Mol Cancer Res; 2004 Apr 15; 2(4):203-14. PubMed ID: 15140942
    [Abstract] [Full Text] [Related]

  • 13. Apoptosis associated with deregulated E2F activity is dependent on E2F1 and Atm/Nbs1/Chk2.
    Rogoff HA, Pickering MT, Frame FM, Debatis ME, Sanchez Y, Jones S, Kowalik TF.
    Mol Cell Biol; 2004 Apr 15; 24(7):2968-77. PubMed ID: 15024084
    [Abstract] [Full Text] [Related]

  • 14. p53 negatively regulates expression of FoxM1.
    Pandit B, Halasi M, Gartel AL.
    Cell Cycle; 2009 Oct 15; 8(20):3425-7. PubMed ID: 19806025
    [Abstract] [Full Text] [Related]

  • 15. Thiostrepton selectively targets breast cancer cells through inhibition of forkhead box M1 expression.
    Kwok JM, Myatt SS, Marson CM, Coombes RC, Constantinidou D, Lam EW.
    Mol Cancer Ther; 2008 Jul 15; 7(7):2022-32. PubMed ID: 18645012
    [Abstract] [Full Text] [Related]

  • 16. The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells.
    Madureira PA, Varshochi R, Constantinidou D, Francis RE, Coombes RC, Yao KM, Lam EW.
    J Biol Chem; 2006 Sep 01; 281(35):25167-76. PubMed ID: 16809346
    [Abstract] [Full Text] [Related]

  • 17. miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer.
    Tan X, Fu Y, Chen L, Lee W, Lai Y, Rezaei K, Tabbara S, Latham P, Teal CB, Man YG, Siegel RS, Brem RF, Fu SW.
    Oncotarget; 2016 Jan 05; 7(1):293-307. PubMed ID: 26588055
    [Abstract] [Full Text] [Related]

  • 18. Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.
    Khongkow P, Gomes AR, Gong C, Man EP, Tsang JW, Zhao F, Monteiro LJ, Coombes RC, Medema RH, Khoo US, Lam EW.
    Oncogene; 2016 Feb 25; 35(8):990-1002. PubMed ID: 25961928
    [Abstract] [Full Text] [Related]

  • 19. p53-dependent down-regulation of telomerase is mediated by p21waf1.
    Shats I, Milyavsky M, Tang X, Stambolsky P, Erez N, Brosh R, Kogan I, Braunstein I, Tzukerman M, Ginsberg D, Rotter V.
    J Biol Chem; 2004 Dec 03; 279(49):50976-85. PubMed ID: 15371422
    [Abstract] [Full Text] [Related]

  • 20. Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes.
    Tan Y, Raychaudhuri P, Costa RH.
    Mol Cell Biol; 2007 Feb 03; 27(3):1007-16. PubMed ID: 17101782
    [Abstract] [Full Text] [Related]

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