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Journal Abstract Search

216 related items for PubMed ID: 21525431

  • 1. Abundance of TRPC6 protein in glomerular mesangial cells is decreased by ROS and PKC in diabetes.
    Graham S, Gorin Y, Abboud HE, Ding M, Lee DY, Shi H, Ding Y, Ma R.
    Am J Physiol Cell Physiol; 2011 Aug; 301(2):C304-15. PubMed ID: 21525431
    [Abstract] [Full Text] [Related]

  • 2. Downregulation of TRPC6 protein expression by high glucose, a possible mechanism for the impaired Ca2+ signaling in glomerular mesangial cells in diabetes.
    Graham S, Ding M, Sours-Brothers S, Yorio T, Ma JX, Ma R.
    Am J Physiol Renal Physiol; 2007 Oct; 293(4):F1381-90. PubMed ID: 17699555
    [Abstract] [Full Text] [Related]

  • 3. Astragaloside IV prevents damage to human mesangial cells through the inhibition of the NADPH oxidase/ROS/Akt/NF‑κB pathway under high glucose conditions.
    Sun L, Li W, Li W, Xiong L, Li G, Ma R.
    Int J Mol Med; 2014 Jul; 34(1):167-76. PubMed ID: 24718766
    [Abstract] [Full Text] [Related]

  • 4. Nuclear factor κB mediates suppression of canonical transient receptor potential 6 expression by reactive oxygen species and protein kinase C in kidney cells.
    Wang Y, Ding M, Chaudhari S, Ding Y, Yuan J, Stankowska D, He S, Krishnamoorthy R, Cunningham JT, Ma R.
    J Biol Chem; 2013 May 03; 288(18):12852-65. PubMed ID: 23525112
    [Abstract] [Full Text] [Related]

  • 5. A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease.
    Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW, Birnbaumer L, Staruschenko A.
    J Am Soc Nephrol; 2018 Jul 03; 29(7):1917-1927. PubMed ID: 29793963
    [Abstract] [Full Text] [Related]

  • 6. Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells.
    Shah A, Xia L, Goldberg H, Lee KW, Quaggin SE, Fantus IG.
    J Biol Chem; 2013 Mar 08; 288(10):6835-48. PubMed ID: 23329835
    [Abstract] [Full Text] [Related]

  • 7. High glucose-suppressed endothelin-1 Ca2+ signaling via NADPH oxidase and diacylglycerol-sensitive protein kinase C isozymes in mesangial cells.
    Hua H, Munk S, Goldberg H, Fantus IG, Whiteside CI.
    J Biol Chem; 2003 Sep 05; 278(36):33951-62. PubMed ID: 12821678
    [Abstract] [Full Text] [Related]

  • 8. EGFR-PLCgamma1 signaling mediates high glucose-induced PKCbeta1-Akt activation and collagen I upregulation in mesangial cells.
    Wu D, Peng F, Zhang B, Ingram AJ, Kelly DJ, Gilbert RE, Gao B, Kumar S, Krepinsky JC.
    Am J Physiol Renal Physiol; 2009 Sep 05; 297(3):F822-34. PubMed ID: 19605547
    [Abstract] [Full Text] [Related]

  • 9. The mTOR promotes oxidative stress-induced apoptosis of mesangial cells in diabetic nephropathy.
    Lu Q, Zhou Y, Hao M, Li C, Wang J, Shu F, Du L, Zhu X, Zhang Q, Yin X.
    Mol Cell Endocrinol; 2018 Sep 15; 473():31-43. PubMed ID: 29277549
    [Abstract] [Full Text] [Related]

  • 10. Suppression of XBP1S mediates high glucose-induced oxidative stress and extracellular matrix synthesis in renal mesangial cell and kidney of diabetic rats.
    Shao D, Liu J, Ni J, Wang Z, Shen Y, Zhou L, Huang Y, Wang J, Xue H, Zhang W, Lu L.
    PLoS One; 2013 Sep 15; 8(2):e56124. PubMed ID: 23457509
    [Abstract] [Full Text] [Related]

  • 11. Mesangial cell NADPH oxidase upregulation in high glucose is protein kinase C dependent and required for collagen IV expression.
    Xia L, Wang H, Goldberg HJ, Munk S, Fantus IG, Whiteside CI.
    Am J Physiol Renal Physiol; 2006 Feb 15; 290(2):F345-56. PubMed ID: 16131649
    [Abstract] [Full Text] [Related]

  • 12. Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species.
    Lee DY, Wauquier F, Eid AA, Roman LJ, Ghosh-Choudhury G, Khazim K, Block K, Gorin Y.
    J Biol Chem; 2013 Oct 04; 288(40):28668-86. PubMed ID: 23940049
    [Abstract] [Full Text] [Related]

  • 13. Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.
    Kim EY, Anderson M, Dryer SE.
    Am J Physiol Renal Physiol; 2012 Feb 01; 302(3):F298-307. PubMed ID: 22031853
    [Abstract] [Full Text] [Related]

  • 14. Combination of leflunomide and benazepril reduces renal injury of diabetic nephropathy rats and inhibits high-glucose induced cell apoptosis through regulation of NF-κB, TGF-β and TRPC6.
    Li H, Wang Y, Zhou Z, Tian F, Yang H, Yan J.
    Ren Fail; 2019 Nov 01; 41(1):899-906. PubMed ID: 31552773
    [Abstract] [Full Text] [Related]

  • 15. Reactive oxygen species, PKC-beta1, and PKC-zeta mediate high-glucose-induced vascular endothelial growth factor expression in mesangial cells.
    Xia L, Wang H, Munk S, Frecker H, Goldberg HJ, Fantus IG, Whiteside CI.
    Am J Physiol Endocrinol Metab; 2007 Nov 01; 293(5):E1280-8. PubMed ID: 17711990
    [Abstract] [Full Text] [Related]

  • 16. Induction of reactive oxygen species from isolated rat glomeruli by protein kinase C activation and TNF-alpha stimulation, and effects of a phosphodiesterase inhibitor.
    Koike N, Takamura T, Kaneko S.
    Life Sci; 2007 Apr 10; 80(18):1721-8. PubMed ID: 17346751
    [Abstract] [Full Text] [Related]

  • 17. Sestrin 2 and AMPK connect hyperglycemia to Nox4-dependent endothelial nitric oxide synthase uncoupling and matrix protein expression.
    Eid AA, Lee DY, Roman LJ, Khazim K, Gorin Y.
    Mol Cell Biol; 2013 Sep 10; 33(17):3439-60. PubMed ID: 23816887
    [Abstract] [Full Text] [Related]

  • 18. Angiotensin II activates two cation conductances with distinct TRPC1 and TRPC6 channel properties in rabbit mesenteric artery myocytes.
    Saleh SN, Albert AP, Peppiatt CM, Large WA.
    J Physiol; 2006 Dec 01; 577(Pt 2):479-95. PubMed ID: 16973707
    [Abstract] [Full Text] [Related]

  • 19. In high glucose protein kinase C-zeta activation is required for mesangial cell generation of reactive oxygen species.
    Kwan J, Wang H, Munk S, Xia L, Goldberg HJ, Whiteside CI.
    Kidney Int; 2005 Dec 01; 68(6):2526-41. PubMed ID: 16316329
    [Abstract] [Full Text] [Related]

  • 20. NADPH oxidase-derived ROS contributes to upregulation of TRPC6 expression in puromycin aminonucleoside-induced podocyte injury.
    Wang Z, Wei X, Zhang Y, Ma X, Li B, Zhang S, Du P, Zhang X, Yi F.
    Cell Physiol Biochem; 2009 Dec 01; 24(5-6):619-26. PubMed ID: 19910702
    [Abstract] [Full Text] [Related]

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