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198 related items for PubMed ID: 21527556
1. Protein kinase D3 sensitizes RAF inhibitor RAF265 in melanoma cells by preventing reactivation of MAPK signaling. Chen J, Shen Q, Labow M, Gaither LA. Cancer Res; 2011 Jun 15; 71(12):4280-91. PubMed ID: 21527556 [Abstract] [Full Text] [Related]
2. Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines. Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W. J Cell Physiol; 2009 Jul 15; 220(1):214-21. PubMed ID: 19288493 [Abstract] [Full Text] [Related]
3. Akt regulates vitamin D3-induced leukemia cell functional differentiation via Raf/MEK/ERK MAPK signaling. Wang J, Zhao Y, Kauss MA, Spindel S, Lian H. Eur J Cell Biol; 2009 Feb 15; 88(2):103-15. PubMed ID: 19058874 [Abstract] [Full Text] [Related]
4. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer. Roberts PJ, Der CJ. Oncogene; 2007 May 14; 26(22):3291-310. PubMed ID: 17496923 [Abstract] [Full Text] [Related]
5. Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease. Zitzmann K, Rüden Jv, Brand S, Göke B, Lichtl J, Spöttl G, Auernhammer CJ. Cancer Lett; 2010 Sep 01; 295(1):100-9. PubMed ID: 20356670 [Abstract] [Full Text] [Related]
6. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells. Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM. J Pharmacol Exp Ther; 2009 Jun 01; 329(3):1063-70. PubMed ID: 19258520 [Abstract] [Full Text] [Related]
7. BRAF V600E disrupts AZD6244-induced abrogation of negative feedback pathways between extracellular signal-regulated kinase and Raf proteins. Friday BB, Yu C, Dy GK, Smith PD, Wang L, Thibodeau SN, Adjei AA. Cancer Res; 2008 Aug 01; 68(15):6145-53. PubMed ID: 18676837 [Abstract] [Full Text] [Related]
9. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma. Yang R, Piperdi S, Gorlick R. Clin Cancer Res; 2008 Oct 15; 14(20):6396-404. PubMed ID: 18927278 [Abstract] [Full Text] [Related]
12. Sorafenib (BAY 43-9006, Nexavar), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature. Adnane L, Trail PA, Taylor I, Wilhelm SM. Methods Enzymol; 2006 Oct 15; 407():597-612. PubMed ID: 16757355 [Abstract] [Full Text] [Related]
14. Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors. Sharma A, Trivedi NR, Zimmerman MA, Tuveson DA, Smith CD, Robertson GP. Cancer Res; 2005 Mar 15; 65(6):2412-21. PubMed ID: 15781657 [Abstract] [Full Text] [Related]
15. Emerging Raf inhibitors. McCubrey JA, Steelman LS, Abrams SL, Chappell WH, Russo S, Ove R, Milella M, Tafuri A, Lunghi P, Bonati A, Stivala F, Nicoletti F, Libra M, Martelli AM, Montalto G, Cervello M. Expert Opin Emerg Drugs; 2009 Dec 15; 14(4):633-48. PubMed ID: 19715444 [Abstract] [Full Text] [Related]
16. 1Alpha,25-dihydroxyvitamin D3-mediated stimulation of steroid sulphatase activity in myeloid leukaemic cell lines requires VDRnuc-mediated activation of the RAS/RAF/ERK-MAP kinase signalling pathway. Hughes PJ, Brown G. J Cell Biochem; 2006 Jun 01; 98(3):590-617. PubMed ID: 16440327 [Abstract] [Full Text] [Related]