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Journal Abstract Search

187 related items for PubMed ID: 21532145

  • 1. Inhibition of Akt (ser473) phosphorylation and rapamycin-resistant cell growth by knockdown of mammalian target of rapamycin with small interfering RNA in vascular endothelial growth factor receptor-1-targeting vector.
    Koide H, Asai T, Furuya K, Tsuzuku T, Kato H, Dewa T, Nango M, Maeda N, Oku N.
    Biol Pharm Bull; 2011; 34(5):602-8. PubMed ID: 21532145
    [Abstract] [Full Text] [Related]

  • 2. Susceptibility of PTEN-positive metastatic tumors to small interfering RNA targeting the mammalian target of rapamycin.
    Koide H, Asai T, Kato H, Yonenaga N, Yokota M, Ando H, Dewa T, Nango M, Maeda N, Oku N.
    Nanomedicine; 2015 Jan; 11(1):185-94. PubMed ID: 25240598
    [Abstract] [Full Text] [Related]

  • 3. Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.
    Lee SL, Chou CC, Chuang HC, Hsu EC, Chiu PC, Kulp SK, Byrd JC, Chen CS.
    PLoS One; 2013 Jan; 8(6):e67149. PubMed ID: 23840605
    [Abstract] [Full Text] [Related]

  • 4. Rapamycin regulates the phosphorylation of rictor.
    Akcakanat A, Singh G, Hung MC, Meric-Bernstam F.
    Biochem Biophys Res Commun; 2007 Oct 19; 362(2):330-3. PubMed ID: 17707343
    [Abstract] [Full Text] [Related]

  • 5. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S, Khuri FR, Roman J.
    Cancer Res; 2006 Jan 01; 66(1):315-23. PubMed ID: 16397245
    [Abstract] [Full Text] [Related]

  • 6. Akt inhibitor A-443654 induces rapid Akt Ser-473 phosphorylation independent of mTORC1 inhibition.
    Han EK, Leverson JD, McGonigal T, Shah OJ, Woods KW, Hunter T, Giranda VL, Luo Y.
    Oncogene; 2007 Aug 16; 26(38):5655-61. PubMed ID: 17334390
    [Abstract] [Full Text] [Related]

  • 7. Inhibition of 14-3-3 binding to Rictor of mTORC2 for Akt phosphorylation at Ser473 is regulated by selenoprotein W.
    Jeon YH, Park YH, Kwon JH, Lee JH, Kim IY.
    Biochim Biophys Acta; 2013 Oct 16; 1833(10):2135-42. PubMed ID: 23680186
    [Abstract] [Full Text] [Related]

  • 8. Reduced menin expression impairs rapamycin effects as evidenced by an increase in mTORC2 signaling and cell migration.
    Razmara M, Monazzam A, Skogseid B.
    Cell Commun Signal; 2018 Oct 01; 16(1):64. PubMed ID: 30285764
    [Abstract] [Full Text] [Related]

  • 9. Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
    Martelli AM, Evangelisti C, Chappell W, Abrams SL, Bäsecke J, Stivala F, Donia M, Fagone P, Nicoletti F, Libra M, Ruvolo V, Ruvolo P, Kempf CR, Steelman LS, McCubrey JA.
    Leukemia; 2011 Jul 01; 25(7):1064-79. PubMed ID: 21436840
    [Abstract] [Full Text] [Related]

  • 10. Akt1 activation can augment hypoxia-inducible factor-1alpha expression by increasing protein translation through a mammalian target of rapamycin-independent pathway.
    Pore N, Jiang Z, Shu HK, Bernhard E, Kao GD, Maity A.
    Mol Cancer Res; 2006 Jul 01; 4(7):471-9. PubMed ID: 16849522
    [Abstract] [Full Text] [Related]

  • 11. Hypoxia-induced endothelial proliferation requires both mTORC1 and mTORC2.
    Li W, Petrimpol M, Molle KD, Hall MN, Battegay EJ, Humar R.
    Circ Res; 2007 Jan 05; 100(1):79-87. PubMed ID: 17110594
    [Abstract] [Full Text] [Related]

  • 12. Protein phosphatase 2A and DNA-dependent protein kinase are involved in mediating rapamycin-induced Akt phosphorylation.
    Li Y, Wang X, Yue P, Tao H, Ramalingam SS, Owonikoko TK, Deng X, Wang Y, Fu H, Khuri FR, Sun SY.
    J Biol Chem; 2013 May 10; 288(19):13215-24. PubMed ID: 23536185
    [Abstract] [Full Text] [Related]

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  • 14. Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase.
    Das F, Ghosh-Choudhury N, Dey N, Mandal CC, Mahimainathan L, Kasinath BS, Abboud HE, Choudhury GG.
    J Biol Chem; 2012 Feb 03; 287(6):3808-22. PubMed ID: 22184110
    [Abstract] [Full Text] [Related]

  • 15. High glucose-induced hypertrophy of mesangial cells is reversed by connexin43 overexpression via PTEN/Akt/mTOR signaling.
    Liu L, Hu X, Cai GY, Lv Y, Zhuo L, Gao JJ, Cui SY, Feng Z, Fu B, Chen XM.
    Nephrol Dial Transplant; 2012 Jan 03; 27(1):90-100. PubMed ID: 21633095
    [Abstract] [Full Text] [Related]

  • 16. Epimagnolin targeting on an active pocket of mammalian target of rapamycin suppressed cell transformation and colony growth of lung cancer cells.
    Yoo SM, Lee CJ, Kang HC, Lee HS, Lee JY, Kim KD, Kim DJ, An HJ, Cho YY.
    Mol Carcinog; 2019 Jul 03; 58(7):1221-1233. PubMed ID: 30887599
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  • 19. Discrete signaling mechanisms of mTORC1 and mTORC2: Connected yet apart in cellular and molecular aspects.
    Jhanwar-Uniyal M, Amin AG, Cooper JB, Das K, Schmidt MH, Murali R.
    Adv Biol Regul; 2017 May 03; 64():39-48. PubMed ID: 28189457
    [Abstract] [Full Text] [Related]

  • 20. PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes PTEN & LKB1 in human uterine leiomyomas.
    Makker A, Goel MM, Mahdi AA, Bhatia V, Das V, Agarwal A, Pandey A.
    Indian J Med Res; 2016 May 03; 143(Supplement):S112-S119. PubMed ID: 27748285
    [Abstract] [Full Text] [Related]

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