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90 related items for PubMed ID: 21538549

  • 1. Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis.
    Ridler K, Plisson C, Rabiner EA, Gunn RN, Easwaramoorthy B, Abi-Dargham A, Laruelle M, Slifstein M.
    Synapse; 2011 Nov; 65(11):1119-27. PubMed ID: 21538549
    [Abstract] [Full Text] [Related]

  • 2. Assessing the sensitivity of [¹¹C]p943, a novel 5-HT1B radioligand, to endogenous serotonin release.
    Cosgrove KP, Kloczynski T, Nabulsi N, Weinzimmer D, Lin SF, Staley JK, Bhagwagar Z, Carson RE.
    Synapse; 2011 Oct; 65(10):1113-7. PubMed ID: 21484884
    [Abstract] [Full Text] [Related]

  • 3. High-resolution imaging of brain 5-HT 1B receptors in the rhesus monkey using [11C]P943.
    Nabulsi N, Huang Y, Weinzimmer D, Ropchan J, Frost JJ, McCarthy T, Carson RE, Ding YS.
    Nucl Med Biol; 2010 Feb; 37(2):205-14. PubMed ID: 20152720
    [Abstract] [Full Text] [Related]

  • 4. [11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain.
    Pierson ME, Andersson J, Nyberg S, McCarthy DJ, Finnema SJ, Varnäs K, Takano A, Karlsson P, Gulyás B, Medd AM, Lee CM, Powell ME, Heys JR, Potts W, Seneca N, Mrzljak L, Farde L, Halldin C.
    Neuroimage; 2008 Jul 01; 41(3):1075-85. PubMed ID: 18434202
    [Abstract] [Full Text] [Related]

  • 5. Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain.
    Finnema SJ, Varrone A, Hwang TJ, Gulyás B, Pierson ME, Halldin C, Farde L.
    Synapse; 2010 Jul 01; 64(7):573-7. PubMed ID: 20222157
    [Abstract] [Full Text] [Related]

  • 6. [N-methyl-3H3]AZ10419369 binding to the 5-HT1B receptor: in vitro characterization and in vivo receptor occupancy.
    Maier DL, Sobotka-Briner C, Ding M, Powell ME, Jiang Q, Hill G, Heys JR, Elmore CS, Pierson ME, Mrzljak L.
    J Pharmacol Exp Ther; 2009 Jul 01; 330(1):342-51. PubMed ID: 19401496
    [Abstract] [Full Text] [Related]

  • 7. Serotonin 1B receptor imaging in alcohol dependence.
    Hu J, Henry S, Gallezot JD, Ropchan J, Neumaier JF, Potenza MN, Sinha R, Krystal JH, Huang Y, Ding YS, Carson RE, Neumeister A.
    Biol Psychiatry; 2010 May 01; 67(9):800-3. PubMed ID: 20172504
    [Abstract] [Full Text] [Related]

  • 8. In vivo serotonin-sensitive binding of [11C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer.
    Milak MS, Severance AJ, Prabhakaran J, Kumar JS, Majo VJ, Ogden RT, Mann JJ, Parsey RV.
    J Cereb Blood Flow Metab; 2011 Jan 01; 31(1):243-9. PubMed ID: 20571518
    [Abstract] [Full Text] [Related]

  • 9. Test-retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943.
    Saricicek A, Chen J, Planeta B, Ruf B, Subramanyam K, Maloney K, Matuskey D, Labaree D, Deserno L, Neumeister A, Krystal JH, Gallezot JD, Huang Y, Carson RE, Bhagwagar Z.
    Eur J Nucl Med Mol Imaging; 2015 Mar 01; 42(3):468-77. PubMed ID: 25427881
    [Abstract] [Full Text] [Related]

  • 10. Inverse changes in raphe and cortical 5-HT1B receptor availability after acute tryptophan depletion in healthy human subjects.
    Baldassarri SR, Park E, Finnema SJ, Planeta B, Nabulsi N, Najafzadeh S, Ropchan J, Huang Y, Hannestad J, Maloney K, Bhagwagar Z, Carson RE.
    Synapse; 2020 Oct 01; 74(10):e22159. PubMed ID: 32324935
    [Abstract] [Full Text] [Related]

  • 11. Kinetic modeling of the serotonin 5-HT(1B) receptor radioligand [(11)C]P943 in humans.
    Gallezot JD, Nabulsi N, Neumeister A, Planeta-Wilson B, Williams WA, Singhal T, Kim S, Maguire RP, McCarthy T, Frost JJ, Huang Y, Ding YS, Carson RE.
    J Cereb Blood Flow Metab; 2010 Jan 01; 30(1):196-210. PubMed ID: 19773803
    [Abstract] [Full Text] [Related]

  • 12. The selective 5-HT1B receptor inverse agonist 1'-methyl-5-[[2'-methyl-4'-(5-methyl-1,2, 4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4'-piperidine] (SB-224289) potently blocks terminal 5-HT autoreceptor function both in vitro and in vivo.
    Gaster LM, Blaney FE, Davies S, Duckworth DM, Ham P, Jenkins S, Jennings AJ, Joiner GF, King FD, Mulholland KR, Wyman PA, Hagan JJ, Hatcher J, Jones BJ, Middlemiss DN, Price GW, Riley G, Roberts C, Routledge C, Selkirk J, Slade PD.
    J Med Chem; 1998 Apr 09; 41(8):1218-35. PubMed ID: 9548813
    [Abstract] [Full Text] [Related]

  • 13. [11C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors.
    Lindberg A, Nag S, Schou M, Takano A, Matsumoto J, Amini N, Elmore CS, Farde L, Pike VW, Halldin C.
    Nucl Med Biol; 2017 Nov 09; 54():34-40. PubMed ID: 28950161
    [Abstract] [Full Text] [Related]

  • 14. Effects of tryptophan depletion on the binding of [11C]-DASB to the serotonin transporter in baboons: response to acute serotonin deficiency.
    Milak MS, Ogden RT, Vinocur DN, Van Heertum RL, Cooper TB, Mann JJ, Parsey RV.
    Biol Psychiatry; 2005 Jan 01; 57(1):102-6. PubMed ID: 15607307
    [Abstract] [Full Text] [Related]

  • 15. A PET study with [11C]AZ10419369 to determine brain 5-HT1B receptor occupancy of zolmitriptan in healthy male volunteers.
    Varnäs K, Jučaite A, McCarthy DJ, Stenkrona P, Nord M, Halldin C, Farde L, Kanes S.
    Cephalalgia; 2013 Jul 01; 33(10):853-60. PubMed ID: 23430984
    [Abstract] [Full Text] [Related]

  • 16. Autoradiographic characterisation of [35S]GTPgammaS binding stimulation mediated by 5-HT1B receptor in postmortem human brain.
    Mostany R, Pazos A, Castro ME.
    Neuropharmacology; 2005 Jan 01; 48(1):25-33. PubMed ID: 15617724
    [Abstract] [Full Text] [Related]

  • 17. (+)-WAY 100135, a partial agonist, at native and recombinant 5-HT1B/1D receptors.
    Davidson C, Ho M, Price GW, Jones BJ, Stamford JA.
    Br J Pharmacol; 1997 Jun 01; 121(4):737-42. PubMed ID: 9208142
    [Abstract] [Full Text] [Related]

  • 18. 5-HT1B receptor-mediated contractions in human temporal artery: evidence from selective antagonists and 5-HT receptor mRNA expression.
    Verheggen R, Hundeshagen AG, Brown AM, Schindler M, Kaumann AJ.
    Br J Pharmacol; 1998 Aug 01; 124(7):1345-54. PubMed ID: 9723944
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.
    Kumar JS, Majo VJ, Hsiung SC, Millak MS, Liu KP, Tamir H, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV.
    J Med Chem; 2006 Jan 12; 49(1):125-34. PubMed ID: 16392798
    [Abstract] [Full Text] [Related]

  • 20. SB-224289--a novel selective (human) 5-HT1B receptor antagonist with negative intrinsic activity.
    Selkirk JV, Scott C, Ho M, Burton MJ, Watson J, Gaster LM, Collin L, Jones BJ, Middlemiss DN, Price GW.
    Br J Pharmacol; 1998 Sep 12; 125(1):202-8. PubMed ID: 9776361
    [Abstract] [Full Text] [Related]

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