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Journal Abstract Search


193 related items for PubMed ID: 21542861

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  • 2. Botulinum neurotoxin serotype D attacks neurons via two carbohydrate-binding sites in a ganglioside-dependent manner.
    Strotmeier J, Lee K, Völker AK, Mahrhold S, Zong Y, Zeiser J, Zhou J, Pich A, Bigalke H, Binz T, Rummel A, Jin R.
    Biochem J; 2010 Oct 15; 431(2):207-16. PubMed ID: 20704566
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  • 6. Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.
    Zhang S, Berntsson RP, Tepp WH, Tao L, Johnson EA, Stenmark P, Dong M.
    Nat Commun; 2017 Nov 21; 8(1):1637. PubMed ID: 29158482
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  • 8. Exchange of the H(CC) domain mediating double receptor recognition improves the pharmacodynamic properties of botulinum neurotoxin.
    Rummel A, Mahrhold S, Bigalke H, Binz T.
    FEBS J; 2011 Dec 21; 278(23):4506-15. PubMed ID: 21624052
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  • 10. Glycosylated SV2 and gangliosides as dual receptors for botulinum neurotoxin serotype F.
    Fu Z, Chen C, Barbieri JT, Kim JJ, Baldwin MR.
    Biochemistry; 2009 Jun 23; 48(24):5631-41. PubMed ID: 19476346
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  • 12. Botulinum neurotoxin B recognizes its protein receptor with high affinity and specificity.
    Jin R, Rummel A, Binz T, Brunger AT.
    Nature; 2006 Dec 21; 444(7122):1092-5. PubMed ID: 17167421
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  • 13. Novel ganglioside-mediated entry of botulinum neurotoxin serotype D into neurons.
    Kroken AR, Karalewitz AP, Fu Z, Kim JJ, Barbieri JT.
    J Biol Chem; 2011 Jul 29; 286(30):26828-37. PubMed ID: 21632541
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  • 15. The HCC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction.
    Rummel A, Mahrhold S, Bigalke H, Binz T.
    Mol Microbiol; 2004 Feb 29; 51(3):631-43. PubMed ID: 14731268
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  • 17. Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding.
    Stenmark P, Dong M, Dupuy J, Chapman ER, Stevens RC.
    J Mol Biol; 2010 Apr 16; 397(5):1287-97. PubMed ID: 20219474
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  • 19. Structural and mutational analyses of the receptor binding domain of botulinum D/C mosaic neurotoxin: insight into the ganglioside binding mechanism.
    Nuemket N, Tanaka Y, Tsukamoto K, Tsuji T, Nakamura K, Kozaki S, Yao M, Tanaka I.
    Biochem Biophys Res Commun; 2011 Jul 29; 411(2):433-9. PubMed ID: 21749855
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  • 20. Exchanging the minimal cell binding fragments of tetanus neurotoxin in botulinum neurotoxin A and B impacts their toxicity at the neuromuscular junction and central neurons.
    Höltje M, Schulze S, Strotmeier J, Mahrhold S, Richter K, Binz T, Bigalke H, Ahnert-Hilger G, Rummel A.
    Toxicon; 2013 Dec 01; 75():108-21. PubMed ID: 23817019
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