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Journal Abstract Search

520 related items for PubMed ID: 21543344

  • 1. Lung-cancer chemoprevention by induction of synthetic lethality in mutant KRAS premalignant cells in vitro and in vivo.
    Huang S, Ren X, Wang L, Zhang L, Wu X.
    Cancer Prev Res (Phila); 2011 May; 4(5):666-73. PubMed ID: 21543344
    [Abstract] [Full Text] [Related]

  • 2. Back to the future: mechanism-based, mutation-specific combination chemoprevention with a synthetic lethality approach.
    Meyskens FL, Gerner EW.
    Cancer Prev Res (Phila); 2011 May; 4(5):628-32. PubMed ID: 21543341
    [Abstract] [Full Text] [Related]

  • 3. Regulation of TRAIL-induced apoptosis by ectopic expression of antiapoptotic factors.
    Aggarwal BB, Bhardwaj U, Takada Y.
    Vitam Horm; 2004 May; 67():453-83. PubMed ID: 15110190
    [Abstract] [Full Text] [Related]

  • 4. Effect of the XIAP inhibitor Embelin on TRAIL-induced apoptosis of pancreatic cancer cells.
    Mori T, Doi R, Kida A, Nagai K, Kami K, Ito D, Toyoda E, Kawaguchi Y, Uemoto S.
    J Surg Res; 2007 Oct; 142(2):281-6. PubMed ID: 17640673
    [Abstract] [Full Text] [Related]

  • 5. TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.
    Deng Y, Lin Y, Wu X.
    Genes Dev; 2002 Jan 01; 16(1):33-45. PubMed ID: 11782443
    [Abstract] [Full Text] [Related]

  • 6. A small molecule Smac-mimic compound induces apoptosis and sensitizes TRAIL- and etoposide-induced apoptosis in breast cancer cells.
    Bockbrader KM, Tan M, Sun Y.
    Oncogene; 2005 Nov 10; 24(49):7381-8. PubMed ID: 16044155
    [Abstract] [Full Text] [Related]

  • 7. Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis of human melanoma is regulated by smac/DIABLO release from mitochondria.
    Zhang XD, Zhang XY, Gray CP, Nguyen T, Hersey P.
    Cancer Res; 2001 Oct 01; 61(19):7339-48. PubMed ID: 11585775
    [Abstract] [Full Text] [Related]

  • 8. MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
    Mohr A, Büneker C, Gough RP, Zwacka RM.
    Oncogene; 2008 Jan 31; 27(6):763-74. PubMed ID: 17653087
    [Abstract] [Full Text] [Related]

  • 9. Bypassing the need for pre-sensitization of cancer cells for anticancer TRAIL therapy with secretion of novel cell penetrable form of Smac from hA-MSCs as cellular delivery vehicle.
    Khorashadizadeh M, Soleimani M, Khanahmad H, Fallah A, Naderi M, Khorramizadeh M.
    Tumour Biol; 2015 Jun 31; 36(6):4213-21. PubMed ID: 25586349
    [Abstract] [Full Text] [Related]

  • 10. Mechanisms of resistance to TRAIL-induced apoptosis in cancer.
    Zhang L, Fang B.
    Cancer Gene Ther; 2005 Mar 31; 12(3):228-37. PubMed ID: 15550937
    [Abstract] [Full Text] [Related]

  • 11. X-linked inhibitor regulating TRAIL-induced apoptosis in chemoresistant human primary glioblastoma cells.
    Roa WH, Chen H, Fulton D, Gulavita S, Shaw A, Th'ng J, Farr-Jones M, Moore R, Petruk K.
    Clin Invest Med; 2003 Oct 31; 26(5):231-42. PubMed ID: 14596484
    [Abstract] [Full Text] [Related]

  • 12. Smac mimetic Birinapant induces apoptosis and enhances TRAIL potency in inflammatory breast cancer cells in an IAP-dependent and TNF-α-independent mechanism.
    Allensworth JL, Sauer SJ, Lyerly HK, Morse MA, Devi GR.
    Breast Cancer Res Treat; 2013 Jan 31; 137(2):359-71. PubMed ID: 23225169
    [Abstract] [Full Text] [Related]

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  • 14. Transfection of Smac/DIABLO sensitizes drug-resistant tumor cells to TRAIL or paclitaxel-induced apoptosis in vitro.
    Mao HL, Liu PS, Zheng JF, Zhang PH, Zhou LG, Xin G, Liu C.
    Pharmacol Res; 2007 Dec 31; 56(6):483-92. PubMed ID: 18029193
    [Abstract] [Full Text] [Related]

  • 15. Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells.
    Izeradjene K, Douglas L, Delaney A, Houghton JA.
    Clin Cancer Res; 2004 Oct 01; 10(19):6650-60. PubMed ID: 15475455
    [Abstract] [Full Text] [Related]

  • 16. Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.
    Fulda S, Wick W, Weller M, Debatin KM.
    Nat Med; 2002 Aug 01; 8(8):808-15. PubMed ID: 12118245
    [Abstract] [Full Text] [Related]

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  • 18. A small molecule Smac mimic potentiates TRAIL-mediated cell death of ovarian cancer cells.
    Petrucci E, Pasquini L, Petronelli A, Saulle E, Mariani G, Riccioni R, Biffoni M, Ferretti G, Benedetti-Panici P, Cognetti F, Scambia G, Humphreys R, Peschle C, Testa U.
    Gynecol Oncol; 2007 May 01; 105(2):481-92. PubMed ID: 17292950
    [Abstract] [Full Text] [Related]

  • 19. EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
    Möller Y, Siegemund M, Beyes S, Herr R, Lecis D, Delia D, Kontermann R, Brummer T, Pfizenmaier K, Olayioye MA.
    PLoS One; 2014 May 01; 9(9):e107165. PubMed ID: 25198428
    [Abstract] [Full Text] [Related]

  • 20. Epithelial-to-Mesenchymal Transition Defines Feedback Activation of Receptor Tyrosine Kinase Signaling Induced by MEK Inhibition in KRAS-Mutant Lung Cancer.
    Kitai H, Ebi H, Tomida S, Floros KV, Kotani H, Adachi Y, Oizumi S, Nishimura M, Faber AC, Yano S.
    Cancer Discov; 2016 Jul 01; 6(7):754-69. PubMed ID: 27154822
    [Abstract] [Full Text] [Related]

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